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8ARV
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BU of 8arv by Molmil
Structure of the EAL domain of BifA from Pseudomonas aeruginosa
分子名称: Bifunctional diguanylate cyclase/phosphodiesterase, MAGNESIUM ION
著者Dias Teixeira, R, Jenal, U, Hiller, S.
登録日2022-08-17
公開日2023-04-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A genetic switch controls Pseudomonas aeruginosa surface colonization.
Nat Microbiol, 8, 2023
2R6O
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BU of 2r6o by Molmil
Crystal structure of putative diguanylate cyclase/phosphodiesterase from Thiobacillus denitrificans
分子名称: CHLORIDE ION, MAGNESIUM ION, Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains)
著者Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-09-06
公開日2007-09-18
最終更新日2012-10-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.
J.Mol.Biol., 402, 2010
4AFY
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BU of 4afy by Molmil
Crystal structure of the FimX EAL domain in complex with reaction product pGpG
分子名称: 5'-R(*GP*GP)-3', FIMX, MAGNESIUM ION, ...
著者Robert-Paganin, J, Nonin-Lecomte, S, Rety, S.
登録日2012-01-23
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structure of an Eal Domain in Complex with Reaction Product 5'-Pgpg
Plos One, 7, 2012
4AG0
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BU of 4ag0 by Molmil
Crystal structure of FimX EAL domain
分子名称: ACETATE ION, FIMX, PHOSPHATE ION
著者Robert-Paganin, J, Nonin-Lecomte, S, Rety, S.
登録日2012-01-23
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Crystal Structure of an Eal Domain in Complex with Reaction Product 5'-Pgpg
Plos One, 7, 2012
4LJ3
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BU of 4lj3 by Molmil
Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Cyclic di-GMP phosphodiesterase YahA, ...
著者Sundriyal, A, Schirmer, T.
登録日2013-07-04
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP.
J.Biol.Chem., 289, 2014
3S83
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BU of 3s83 by Molmil
EAL domain of phosphodiesterase PdeA
分子名称: GGDEF family protein, POTASSIUM ION
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2011-05-27
公開日2011-06-29
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal structure of EAL domain from Caulobacter crescentus CB15
To be Published
5YRP
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BU of 5yrp by Molmil
Crystal structure of the EAL domain of Mycobacterium smegmatis DcpA
分子名称: MAGNESIUM ION, Sensory box/response regulator
著者Chen, H.J, li, N, Luo, Y, Jiang, Y.L, Zhou, C.Z, Chen, Y, Li, Q.
登録日2017-11-09
公開日2018-05-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The GDP-switched GAF domain of DcpA modulates the concerted synthesis/hydrolysis of c-di-GMP inMycobacterium smegmatis.
Biochem. J., 475, 2018
4LYK
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BU of 4lyk by Molmil
Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with activating cofactor Mg++
分子名称: 1,2-ETHANEDIOL, Cyclic di-GMP phosphodiesterase YahA, MAGNESIUM ION, ...
著者Sundriyal, A, Schirmer, T.
登録日2013-07-31
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP.
J.Biol.Chem., 289, 2014
3U2E
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BU of 3u2e by Molmil
EAL domain of phosphodiesterase PdeA in complex with 5'-pGpG and Mg++
分子名称: GGDEF family protein, MAGNESIUM ION, RNA (5'-R(P*GP*G)-3')
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2011-10-03
公開日2011-10-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献EAL domain from Caulobacter crescentus in complex with 5'-pGpG and Mg++
To be Published
4Q6J
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BU of 4q6j by Molmil
Crystal Structure of EAL domain Protein from Listeria monocytogenes EGD-e
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, GLYCEROL, ...
著者Kim, Y, Bigelow, L, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-04-22
公開日2014-05-07
実験手法X-RAY DIFFRACTION (1.369 Å)
主引用文献Crystal Structure of EAL domain Protein from Listeria monocytogenes EGD-e
To be Published
4RNJ
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BU of 4rnj by Molmil
PaMorA phosphodiesterase domain, apo form
分子名称: Motility regulator
著者Phippen, C.W, Tews, I.
登録日2014-10-24
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4RNI
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BU of 4rni by Molmil
PaMorA dimeric phosphodiesterase. apo form
分子名称: Motility regulator
著者Phippen, C.W, Tews, I.
登録日2014-10-24
公開日2014-11-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
5M1T
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BU of 5m1t by Molmil
PaMucR Phosphodiesterase, c-di-GMP complex
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, MucR Phosphodiesterase
著者Hutchin, A, Tews, I, Walsh, M.A.
登録日2016-10-10
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.
Sci Rep, 7, 2017
5MF5
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BU of 5mf5 by Molmil
PA3825-EAL Mg-CdG Structure
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate phosphodiesterase, MAGNESIUM ION
著者Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M.
登録日2016-11-17
公開日2016-12-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.
Sci Rep, 7, 2017
5MFU
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BU of 5mfu by Molmil
PA3825-EAL Mn-pGpG Structure
分子名称: Diguanylate phosphodiesterase, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
著者Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M.
登録日2016-11-18
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.
Sci Rep, 7, 2017
4Y8E
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BU of 4y8e by Molmil
PA3825-EAL Ca-Apo Structure
分子名称: CALCIUM ION, PA3825 EAL
著者Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M.
登録日2015-02-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structure of PA3825 from P. aeruginosa bound to cyclic di-GMP and pGpG: new insights for a potential three-metal catalytic mechanism of EAL domains
To Be Published
4Y9M
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BU of 4y9m by Molmil
PA3825-EAL Metal-Free-Apo Structure
分子名称: PA3825-EAL, PHOSPHATE ION
著者Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A.
登録日2015-02-17
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.
Sci Rep, 7, 2017
4Y9O
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BU of 4y9o by Molmil
PA3825-EAL Metal-Free-Apo Structure - Manganese Co-crystallisation
分子名称: PA3825-EAL, PHOSPHATE ION
著者Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A.
登録日2015-02-17
公開日2016-09-14
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献MucR and PA3825 EAL-phosphodiesterase domains from Pseudomonas aeruginosa suggest roles for three metals in the active site
To Be Published
4Y9N
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BU of 4y9n by Molmil
PA3825-EAL Metal-Free-Apo Structure - Magnesium Co-crystallisation
分子名称: PA3825-EAL, PHOSPHATE ION
著者Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A.
登録日2015-02-17
公開日2016-03-09
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure of PA3825 from P. aeruginosa bound to cyclic di-GMP and pGpG: new insights for a potential three-metal catalytic mechanism of EAL domains
To Be Published
4Y9P
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BU of 4y9p by Molmil
PA3825-EAL Ca-CdG Structure
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, PA3825-EAL
著者Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A.
登録日2015-02-17
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献MucR and PA3825 EAL-phosphodiesterase domains from Pseudomonas aeruginosa suggest roles for three metals in the active site
To Be Published
6IH7
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BU of 6ih7 by Molmil
Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - 3',3'-cGAMP bound form
分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, cyclic di nucleotide phoshodiesterase
著者Yadav, M, Pal, K, Sen, U.
登録日2018-09-28
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
Biochem.J., 476, 2019
6IH1
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BU of 6ih1 by Molmil
Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - c-di-GMP bound form
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, cyclic di nucleotide phoshodiesterase
著者Yadav, M, Pal, K, Sen, U.
登録日2018-09-28
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
Biochem.J., 476, 2019
6IFQ
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BU of 6ifq by Molmil
Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - Apo form
分子名称: CALCIUM ION, cyclic di nucleotide phoshodiesterase
著者Yadav, M, Pal, K, Sen, U.
登録日2018-09-20
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
Biochem.J., 476, 2019
6IJ2
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BU of 6ij2 by Molmil
Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - 5'-pGpG bound form
分子名称: CALCIUM ION, EAL domain protein, RNA (5'-R(P*GP*G)-3')
著者Yadav, M, Pal, K, Sen, U.
登録日2018-10-08
公開日2019-10-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
Biochem.J., 476, 2019
3N3T
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BU of 3n3t by Molmil
Crystal structure of putative diguanylate cyclase/phosphodiesterase complex with cyclic di-gmp
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, MAGNESIUM ION, ...
著者Chang, C, Xu, X, Cui, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-05-20
公開日2010-06-16
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.
J.Mol.Biol., 402, 2010

 

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