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2XNK
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Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1
Descriptor: DNA TOPOISOMERASE 2-BINDING PROTEIN 1, GLYCEROL
Authors:Rappas, M, Oliver, A.W, Pearl, L.H.
Deposit date:2010-08-03
Release date:2010-09-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1.
Nucleic Acids Res., 39, 2011
2XNH
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Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1
Descriptor: DNA TOPOISOMERASE 2-BINDING PROTEIN 1, IODIDE ION
Authors:Rappas, M, Oliver, A.W, Pearl, L.H.
Deposit date:2010-08-02
Release date:2010-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1.
Nucleic Acids Res., 39, 2011
3AL3
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Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex
Descriptor: DNA topoisomerase 2-binding protein 1, FORMIC ACID, Peptide of Fanconi anemia group J protein
Authors:Leung, C.C, Glover, J.N.
Deposit date:2010-07-22
Release date:2010-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3AL2
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Crystal Structure of TopBP1 BRCT7/8
Descriptor: DNA topoisomerase 2-binding protein 1, SULFATE ION
Authors:Leung, C.C, Glover, J.N.
Deposit date:2010-07-22
Release date:2010-12-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3L46
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Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)
Descriptor: Protein ECT2, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L, Tempel, W, Tong, Y, Crombet, L, Wang, H, Guan, X, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2009-12-18
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)
to be published
3K16
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Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K15
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Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0H
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The crystal structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0K
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Crystal Structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus.
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3JVE
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Crystal Structure of the Sixth BRCT Domain of TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
Deposit date:2009-09-16
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
3II6
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Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.
Descriptor: CHLORIDE ION, DNA ligase 4, DNA repair protein XRCC4
Authors:Meesala, S, Junop, M.
Deposit date:2009-07-31
Release date:2009-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4
MOL.CELL.BIOL., 11, 2009
3FA2
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Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains
Descriptor: BRCA1-associated RING domain protein 1, GLYCEROL, PHOSPHATE ION
Authors:Fox III, D, Le Trong, I, Stenkamp, R.E, Klevit, R.E.
Deposit date:2008-11-14
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains
TO BE PUBLISHED
2K7F
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HADDOCK calculated model of the complex between the BRCT region of RFC p140 and dsDNA
Descriptor: 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3', Replication factor C subunit 1
Authors:Kobayashi, M, Ab, E, Bonvin, A, Siegal, G.
Deposit date:2008-08-10
Release date:2009-09-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex.
J.Biol.Chem., 285, 2010
2K6G
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Solution structure of the DNA binding BRCT domain from the large subunit of human Replication Factor C
Descriptor: Replication factor C subunit 1
Authors:Kobayashi, M, Siegal, G, Ab, E, Bonvin, A.M.J.J.
Deposit date:2008-07-09
Release date:2009-09-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the DNA bound BRCT domain from human Replication Factor C p140
To be Published
2VXB
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BU of 2vxb by Molmil
Structure of the Crb2-BRCT2 domain
Descriptor: DNA REPAIR PROTEIN RHP9, PRASEODYMIUM ION
Authors:Kilkenny, M.L, Roe, S.M, Pearl, L.H.
Deposit date:2008-07-03
Release date:2008-08-12
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Analysis of the Crb2-Brct2 Domain Reveals Distinct Roles in Checkpoint Signaling and DNA Damage Repair.
Genes Dev., 22, 2008
2VXC
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Structure of the Crb2-BRCT2 domain complex with phosphopeptide.
Descriptor: DNA REPAIR PROTEIN RHP9, H2A1 PEPTIDE, PRASEODYMIUM ION
Authors:Kilkenny, M.L, Roe, S.M, Pearl, L.H.
Deposit date:2008-07-03
Release date:2008-08-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Analysis of the Crb2-Brct2 Domain Reveals Distinct Roles in Checkpoint Signaling and DNA Damage Repair.
Genes Dev., 22, 2008
3COJ
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BU of 3coj by Molmil
Crystal Structure of the BRCT Domains of Human BRCA1 in Complex with a Phosphorylated Peptide from Human Acetyl-CoA Carboxylase 1
Descriptor: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein
Authors:Shen, Y, Tong, L.
Deposit date:2008-03-28
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1
Biochemistry, 47, 2008
2R1Z
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BU of 2r1z by Molmil
Crystal Structure of the BARD1 BRCT Repeat
Descriptor: BRCA1-associated RING domain protein 1, GLYCEROL
Authors:Lee, M.S, Edwards, R.A, Williams, R.S, Glover, M.J.N.
Deposit date:2007-08-23
Release date:2007-09-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the BARD1 BRCT Repeat
To be Published
2OWO
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Last Stop on the Road to Repair: Structure of E.coli DNA Ligase Bound to Nicked DNA-Adenylate
Descriptor: 26-MER, 5'-D(*AP*CP*AP*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*C)-3', 5'-D(*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*G)-3', ...
Authors:Shuman, S, Nandakumar, J, Nair, P.A.
Deposit date:2007-02-16
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Last Stop on the Road to Repair: Structure of E. coli DNA Ligase Bound to Nicked DNA-Adenylate.
Mol.Cell, 26, 2007
2EBU
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BU of 2ebu by Molmil
Solution structure of the BRCT domain from human replication factor C large subunit 1
Descriptor: Replication factor C subunit 1
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-09
Release date:2007-08-14
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the BRCT domain from human replication factor C large subunit 1
To be Published
2EBW
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Solution structure of the BRCT domain from human DNA repair protein REV1
Descriptor: DNA repair protein REV1
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-09
Release date:2007-08-14
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the BRCT domain from human DNA repair protein REV1
To be Published
2E2W
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Solution structure of the first BRCT domain of human DNA ligase IV
Descriptor: DNA ligase 4
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-11-17
Release date:2006-12-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the first BRCT domain of human DNA ligase IV
TO BE PUBLISHED
2NTE
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Crystal Structure of the BARD1 BRCT Domains
Descriptor: 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ...
Authors:Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A.
Deposit date:2006-11-07
Release date:2007-06-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
2ING
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X-ray Structure of the BRCA1 BRCT mutant M1775K
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Birrane, G, Soni, A, Ladias, J.A.A.
Deposit date:2006-10-07
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2D8M
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Solution structure of the first BRCT domain of DNA-repair protein XRCC1
Descriptor: DNA-repair protein XRCC1
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-06
Release date:2006-06-06
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the first BRCT domain of DNA-repair protein XRCC1
To be published

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