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5VB2
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BU of 5vb2 by Molmil
Crystal structure of the NavAb voltage-gated sodium channel in a closed conformation
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, ...
Authors:Lenaeus, M.J, Catterall, W.A.
Deposit date:2017-03-28
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of closed and open states of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4F4L
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BU of 4f4l by Molmil
Open Channel Conformation of a Voltage Gated Sodium Channel
Descriptor: Ion transport protein
Authors:McCusker, E.C, Bagneris, C, Naylor, C.E, Cole, A.R, D'Avanzo, N, Nichols, C.G, Wallace, B.A.
Deposit date:2012-05-10
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing.
Nat Commun, 3, 2012
5OQK
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BU of 5oqk by Molmil
Solution NMR structure of truncated, human Hv1/VSOP (Voltage-gated proton channel)
Descriptor: Voltage-gated hydrogen channel 1
Authors:Bayrhuber, M, Maslennikov, I, Kwiatowski, W, Sobol, A, Wierschem, C, Eichmann, C, Riek, R.
Deposit date:2017-08-12
Release date:2019-04-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Solution Structure and Functional Behavior of the Human Proton Channel.
Biochemistry, 58, 2019
2A0L
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BU of 2a0l by Molmil
Crystal structure of KvAP-33H1 Fv complex
Descriptor: 33H1 Fv fragment, POTASSIUM ION, Voltage-gated potassium channel
Authors:Lee, S.Y, Lee, A, Chen, J, Mackinnon, R.
Deposit date:2005-06-16
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2KYH
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BU of 2kyh by Molmil
Solution structure of the voltage-sensing domain of KvAP
Descriptor: Voltage-gated potassium channel
Authors:Butterwick, J.A, MacKinnon, R.
Deposit date:2010-05-26
Release date:2010-09-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure and Phospholipid Interactions of the Isolated Voltage-Sensor Domain from KvAP.
J.Mol.Biol., 403, 2010
5KMF
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BU of 5kmf by Molmil
Structure of CavAb in complex with nimodipine
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
Authors:Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2016-06-26
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KLG
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BU of 5klg by Molmil
Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
Authors:Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2016-06-24
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
3ZJZ
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BU of 3zjz by Molmil
Open-form NavMS Sodium Channel Pore (with C-terminal Domain)
Descriptor: DODECAETHYLENE GLYCOL, HEGA-10, ION TRANSPORT PROTEIN, ...
Authors:Bagneris, C, Naylor, C.E, Wallace, B.A.
Deposit date:2013-01-21
Release date:2013-10-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Role of the C-Terminal Domain in the Structure and Function of Tetrameric Sodium Channels.
Nat.Commun., 4, 2013
5BZB
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BU of 5bzb by Molmil
NavMs voltage-gated sodium channel pore and C-terminal domain
Descriptor: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ...
Authors:Naylor, C.E, Bagneris, C, Wallace, B.A.
Deposit date:2015-06-11
Release date:2016-02-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
4X8A
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BU of 4x8a by Molmil
NavMS pore and C-terminal domain grown from protein purified in LiCl
Descriptor: HEGA-10, Ion transport protein, NONAETHYLENE GLYCOL, ...
Authors:Naylor, C.E, Bagneris, C, Wallace, B.A.
Deposit date:2014-12-10
Release date:2016-03-09
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
4X88
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BU of 4x88 by Molmil
E178D Selectivity filter mutant of NavMS voltage-gated pore
Descriptor: HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ...
Authors:Naylor, C.E, Bagneris, C, Wallace, B.A.
Deposit date:2014-12-10
Release date:2016-02-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
4X89
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BU of 4x89 by Molmil
NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate
Descriptor: HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ...
Authors:Naylor, C.E, Bagneris, C, Wallace, B.A.
Deposit date:2014-12-10
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
3RVZ
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BU of 3rvz by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.8 A)
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
Authors:Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
3RW0
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BU of 3rw0 by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Met221Cys, 2.95 A)
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
Authors:Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
3RVY
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BU of 3rvy by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A)
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
Authors:Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
4G7Y
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BU of 4g7y by Molmil
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.8 A)
Descriptor: CHLORIDE ION, Fragment antibody heavy chain, Fragment antibody light chain, ...
Authors:Li, Q.
Deposit date:2012-07-20
Release date:2014-02-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
5KMD
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BU of 5kmd by Molmil
Structure of CavAb in complex with amlodipine
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
Authors:Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2016-06-26
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KLB
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BU of 5klb by Molmil
Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ...
Authors:Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2016-06-23
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KLS
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BU of 5kls by Molmil
Structure of CavAb in complex with Br-dihydropyridine derivative UK-59811
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
Authors:Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2016-06-25
Release date:2016-08-31
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KMH
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BU of 5kmh by Molmil
Structure of CavAb in complex with Br-verapamil
Descriptor: (2~{R})-2-(2-bromophenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ...
Authors:Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2016-06-27
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
4G80
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BU of 4g80 by Molmil
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (WT, 3.8 A)
Descriptor: Voltage-sensor containing phosphatase, fragment antibody heavy chain, fragment antibody light chain
Authors:Li, Q.
Deposit date:2012-07-20
Release date:2014-02-05
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
4G7V
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BU of 4g7v by Molmil
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)
Descriptor: CHLORIDE ION, LAURYL DIMETHYLAMINE-N-OXIDE, SUCCINIC ACID, ...
Authors:Li, Q.
Deposit date:2012-07-20
Release date:2014-02-05
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
4BGN
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BU of 4bgn by Molmil
cryo-EM structure of the NavCt voltage-gated sodium channel
Descriptor: VOLTAGE-GATED SODIUM CHANNEL
Authors:Tsai, C.J, Tani, K, Irie, K, Hiroaki, Y, Shimomura, T, Mcmillan, D.G, Cook, G.M, Schertler, G, Fujiyoshi, Y, Li, X.D.
Deposit date:2013-03-28
Release date:2013-07-10
Last modified:2023-12-20
Method:ELECTRON CRYSTALLOGRAPHY (9 Å)
Cite:Two Alternative Conformations of a Voltage-Gated Sodium Channel.
J.Mol.Biol., 425, 2013
4DXW
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BU of 4dxw by Molmil
Crystal structure of NavRh, a voltage-gated sodium channel
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
Authors:Zhang, X, Ren, W.L, Yan, C.Y, Wang, J.W, Yan, N.
Deposit date:2012-02-28
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
Nature, 486, 2012
4CBC
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BU of 4cbc by Molmil
Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak
Descriptor: HEGA-10, ION TRANSPORT PROTEIN, SODIUM ION
Authors:Bagneris, C, Naylor, C.E, Wallace, B.A.
Deposit date:2013-10-12
Release date:2014-05-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.664 Å)
Cite:Prokaryotic Navms Channel as a Structural and Functional Model for Eukaryotic Sodium Channel Antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014

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