5KJR
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4OM1
| Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2014-01-25 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.131 Å) | 主引用文献 | Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
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1B03
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2BF1
| Structure of an unliganded and fully-glycosylated SIV gp120 envelope glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, B, Vogan, E.M, Gong, H, Skehel, J.J, Wiley, D.C, Harrison, S.C. | 登録日 | 2004-12-02 | 公開日 | 2005-02-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structure of an Unliganded Simian Immunodeficiency Virus Gp120 Core Nature, 433, 2005
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3NGB
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1YYL
| crystal structure of CD4M33, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4M33, scorpion-toxin mimic of CD4, ... | 著者 | Huang, C.C, Stricher, F, Martin, L, Decker, J.M, Majeed, S, Barthe, P, Hendrickson, W.A, Robinson, J, Roumestand, C, Sodroski, J, Wyatt, R, Shaw, G.M, Vita, C, Kwong, P.D. | 登録日 | 2005-02-25 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure, 13, 2005
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2I60
| Crystal structure of [Phe23]M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B HEAVY CHAIN, ANTIBODY 17B LIGHT CHAIN, ... | 著者 | Huang, C.-C, Kwong, P.D. | 登録日 | 2006-08-26 | 公開日 | 2006-10-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein. J.Mol.Biol., 382, 2008
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1YYM
| crystal structure of F23, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), ... | 著者 | Huang, C.C, Stricher, F, Martin, L, Decker, J.M, Majeed, S, Barthe, P, Hendrickson, W.A, Robinson, J, Roumestand, C, Sodroski, J, Wyatt, R, Shaw, G.M, Vita, C, Kwong, P.D. | 登録日 | 2005-02-25 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure, 13, 2005
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3TGQ
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3TGS
| Crystal structure of HIV-1 clade C strain C1086 gp120 core in complex with NBD-556 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade C1086 gp120 core, N-(4-chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2011-08-17 | 公開日 | 2012-04-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109, 2012
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3DNO
| Molecular structure for the HIV-1 gp120 trimer in the CD4-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3DNN
| Molecular structure for the HIV-1 gp120 trimer in the unliganded state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3SE8
| Crystal structure of broadly and potently neutralizing antibody VRC03 in complex with HIV-1 gp120 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kwong, P.D, Zhou, T. | 登録日 | 2011-06-10 | 公開日 | 2011-08-10 | 最終更新日 | 2021-04-07 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
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5WB9
| Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | 著者 | Gohain, N, Tolbert, W, Pazgier, M. | 登録日 | 2017-06-28 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell, 173, 2018
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3FUS
| Improved Structure of the Unliganded Simian Immunodeficiency Virus gp120 Core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, X, Poon, B, Wang, Q, Ma, J. | 登録日 | 2009-01-14 | 公開日 | 2009-06-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinement. Acta Crystallogr.,Sect.D, 65, 2009
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3DNL
| Molecular structure for the HIV-1 gp120 trimer in the b12-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3SE9
| Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kwong, P.D, Zhou, T. | 登録日 | 2011-06-10 | 公開日 | 2011-08-10 | 最終更新日 | 2021-04-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
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5W4L
| Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody N12-i3 Fab heavy chain, Antibody N12-i3 light chain, ... | 著者 | Tolbert, W.D, Gohain, N, Pazgier, M. | 登録日 | 2017-06-12 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region. Structure, 25, 2017
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3TGR
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3TGT
| Crystal structure of unliganded HIV-1 clade A/E strain 93TH057 gp120 core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 clade A/E 93TH057 gp120 | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2011-08-17 | 公開日 | 2012-04-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109, 2012
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5IGX
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5I9Q
| Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC55 Fab heavy chain, ... | 著者 | Scharf, L, Chen, C, Bjorkman, P.J. | 登録日 | 2016-02-20 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for germline antibody recognition of HIV-1 immunogens. Elife, 5, 2016
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8GDJ
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8GDK
| Crystal Structure of HIV-1 LM/HT CLADE A/E CRF01 GP120 Core in Complex with TFH-II-151 | 分子名称: | (3S,5R)-N-(4-chloro-3-fluorophenyl)-5-(hydroxymethyl)-1-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Tolbert, W.D, Nguyen, D.N, Pazgier, M. | 登録日 | 2023-03-06 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal Structure of HIV-1 LM/HT CLADE A/E CRF01 GP120 Core in Complex with TFH-II-151 To Be Published
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8GJT
| Crystal Structure of HIV-1 LM/HT Clade A/E CRF01 GP120 Core in Complex with TFH-I-116-D1 | 分子名称: | (3S)-N-(4-chloro-3-fluorophenyl)-1-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Tolbert, W.D, Nguyen, D.N, Pazgier, M. | 登録日 | 2023-03-16 | 公開日 | 2023-06-07 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC. Viruses, 15, 2023
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