PDB: 288 件ウェブページステータス検索Chemie searchBIRD

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5UMZ	Structure of TNRC6A NLS in complex with importin-alpha 分子名称: GLYCEROL, Importin subunit alpha-1, TNRC6A 著者 Chaston, J, Stewart, A.G, Christie, M. 登録日 2017-01-30 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha. PLoS ONE, 12, 2017
3UL1	Mouse importin alpha: nucleoplasmin cNLS peptide complex 分子名称: Importin subunit alpha-2, Nucleoplasmin 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
4EV8	Crystal structure of mouse catenin beta-59 in 2.4M urea. 分子名称: Catenin beta-1, UREA 著者 Wang, C, Zhang, G.Y. 登録日 2012-04-26 公開日 2013-05-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of mouse catenin beta-59 in 2.4M urea. TO BE PUBLISHED
7RFZ	Importin alpha 2 in complex with MERS ORF4B NLS peptide 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
5HUW	Structure of HSV-1 Large Terminase NLS bound to importin alpha 分子名称: HSV1 large terminase NLS, Importin subunit alpha-1 著者 Sankhala, R.S, Lokareddy, R.K, Cingolani, G. 登録日 2016-01-27 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits. J.Biol.Chem., 291, 2016
4U5U	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
7JK7	Crystal structure of Importin alpha 2 in complex with LSD1 NLS S111E mutant 分子名称: GLYCEROL, Importin subunit alpha-1, Lysine-specific histone demethylase 1A 著者 Tu, W.J, McCuaig, R, Tan, A.H.Y, Hardy, K, Seddiki, N, Ali, S, Dahlstron, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. 登録日 2020-07-27 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
4U5V	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
5HUY	Structure of HCMV Small Terminase NLS bound to importin alpha 分子名称: HCMV small terminase, Importin subunit alpha-1 著者 Sankhala, R.S, Lokareddy, R.K, Cingolani, G. 登録日 2016-01-28 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits. J.Biol.Chem., 291, 2016
5W4F	Importin binding to pol Mu NLS peptide 分子名称: DNA-directed DNA/RNA polymerase mu, GLYCEROL, Importin subunit alpha-1 著者 Pedersen, L.C, London, R.E. 登録日 2017-06-10 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.984 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
7UMI	Importin a1 bound to Cp183-CTD 分子名称: HBV-NLS, Importin subunit alpha-1 著者 Yang, R, Cingolani, G. 登録日 2022-04-07 公開日 2023-10-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
6P6E	Structure of Mouse Importin alpha - PAC3 NLS peptide complex 分子名称: Importin subunit alpha-1, PAC3 NLS 著者 Bernardes, N.E, Silva, T.D, Fukuda, C.A, Oliveira, H.C, Fontes, M.R.M. 登録日 2019-06-03 公開日 2020-01-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha. Sci Rep, 10, 2020
5B6G	Protein-protein interaction 分子名称: Adenomatous polyposis coli protein, GLYCEROL, PHQ-ALA-GLY-GLU-ALA-XYC-TYR-GLU, ... 著者 Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. 登録日 2016-05-27 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
4BQK	rice importin_alpha : VirD2NLS complex 分子名称: DI(HYDROXYETHYL)ETHER, IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER ENDONUCLEASE VIRD2 著者 Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. 登録日 2013-05-31 公開日 2014-02-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha Mol.Plant, 7, 2014
8TUQ	STL Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-17 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
1WA5	Structure of the Cse1:Imp-alpha:RanGTP complex 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ... 著者 Stewart, M. 登録日 2004-10-23 公開日 2004-12-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the assembly of a nuclear export complex. Nature, 432, 2004
7RG0	Importin alpha2 in complex with MERS ORF4B R24A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG2	Importin alpha2 in complex with MERS ORF4B R33A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG3	Importin alpha2 in complex with MERS ORF4B R37A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
5EKF	Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1 分子名称: DNA repair protein complementing XP-G cells, Importin subunit alpha-1 著者 Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. 登録日 2015-11-03 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428, 2016
5WUM	Crystal structure of mouse importin-alpha1 bound to S385-phosphorylated NLS of EBNA1 分子名称: Epstein-Barr nuclear antigen 1, Importin subunit alpha-1 著者 Nakada, R, Hirano, H, Matsuura, Y. 登録日 2016-12-19 公開日 2017-01-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal. Biochem. Biophys. Res. Commun., 484, 2017
3UL0	Mouse importin alpha: mouse CBP80Y8D cNLS complex 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
5SVZ	HIV-1 Tat NLS in complex with importin alpha 分子名称: Importin subunit alpha-1, Tat 著者 Smith, K.M, Himiari, Z, Forwood, J.K. 登録日 2016-08-08 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Importin-alpha Binding of the Human Immunodeficiency Virus Tat. Sci Rep, 7, 2017
8QXW	HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2 分子名称: DNA polymerase processivity factor, Importin subunit alpha-1 著者 Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. 登録日 2023-10-25 公開日 2023-11-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. Febs Lett., 598, 2024
1I7W	BETA-CATENIN/PHOSPHORYLATED E-CADHERIN COMPLEX 分子名称: BETA-CATENIN, CHLORIDE ION, EPITHELIAL-CADHERIN, ... 著者 Huber, A.H, Weis, W.I. 登録日 2001-03-10 公開日 2001-05-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell(Cambridge,Mass.), 105, 2001

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