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6U0M
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BU of 6u0m by Molmil
Structure of the S. cerevisiae replicative helicase CMG in complex with a forked DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (15-MER), ...
著者Yuan, Z, Georgescu, R, Bai, L, Zhang, D, O'Donnell, M, Li, H.
登録日2019-08-14
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
Nat Commun, 11, 2020
6PTJ
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BU of 6ptj by Molmil
Structure of Ctf4 trimer in complex with one CMG helicase
分子名称: Cell division control protein 45, DNA polymerase alpha-binding protein, DNA replication complex GINS protein PSF1, ...
著者Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
登録日2019-07-15
公開日2019-11-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6PTO
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BU of 6pto by Molmil
Structure of Ctf4 trimer in complex with three CMG helicases
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
著者Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
登録日2019-07-16
公開日2019-11-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6PTN
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BU of 6ptn by Molmil
Structure of Ctf4 trimer in complex with two CMG helicases
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
著者Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
登録日2019-07-16
公開日2019-11-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6RQC
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BU of 6rqc by Molmil
Cryo-EM structure of an MCM loading intermediate
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ...
著者Miller, T.C.R, Locke, J, Costa, A.
登録日2019-05-15
公開日2019-11-20
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Nature, 575, 2019
6RAZ
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BU of 6raz by Molmil
D. melanogaster CMG-DNA, State 2B
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ...
著者Eickhoff, P, Martino, F, Costa, A.
登録日2019-04-08
公開日2019-09-18
最終更新日2021-01-20
実験手法ELECTRON MICROSCOPY (4.46 Å)
主引用文献Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
6RAW
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BU of 6raw by Molmil
D. melanogaster CMG-DNA, State 1A
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ...
著者Eickhoff, P, Martino, F, Costa, A.
登録日2019-04-08
公開日2019-09-11
最終更新日2019-09-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
6RAX
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BU of 6rax by Molmil
D. melanogaster CMG-DNA, State 1B
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ...
著者Eickhoff, P, Martino, F, Costa, A.
登録日2019-04-08
公開日2019-09-11
最終更新日2019-09-18
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
6RAY
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BU of 6ray by Molmil
D. melanogaster CMG-DNA, State 2A
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ...
著者Eickhoff, P, Martino, F, Costa, A.
登録日2019-04-08
公開日2019-09-11
最終更新日2019-09-18
実験手法ELECTRON MICROSCOPY (4.28 Å)
主引用文献Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
6MII
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BU of 6mii by Molmil
Crystal structure of minichromosome maintenance protein MCM/DNA complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Enemark, E.J, Meagher, M, Epling, L.B.
登録日2018-09-19
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献DNA translocation mechanism of the MCM complex and implications for replication initiation.
Nat Commun, 10, 2019
6HV9
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BU of 6hv9 by Molmil
S. cerevisiae CMG-Pol epsilon-DNA
分子名称: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ...
著者Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A.
登録日2018-10-10
公開日2018-12-12
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.98 Å)
主引用文献Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
6EYC
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BU of 6eyc by Molmil
Re-refinement of the MCM2-7 double hexamer using ISOLDE
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ...
著者Croll, T.I.
登録日2017-11-11
公開日2018-06-20
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps.
Acta Crystallogr D Struct Biol, 74, 2018
6F0L
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BU of 6f0l by Molmil
S. cerevisiae MCM double hexamer bound to duplex DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (62-MER), DNA replication licensing factor MCM2, ...
著者Abid Ali, F, Pye, V.E, Douglas, M.E, Locke, J, Nans, A, Diffley, J.F.X, Costa, A.
登録日2017-11-20
公開日2017-12-06
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.77 Å)
主引用文献Cryo-EM structure of a licensed DNA replication origin.
Nat Commun, 8, 2017
5BK4
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BU of 5bk4 by Molmil
Cryo-EM structure of Mcm2-7 double hexamer on dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (60-mer), strand 1, ...
著者Li, H, Yuan, Z, Bai, L.
登録日2017-09-12
公開日2017-10-25
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V8F
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BU of 5v8f by Molmil
Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1
分子名称: Cell division control protein 6, Cell division cycle protein CDT1, DNA (39-MER), ...
著者Yuan, Z, Riera, A, Bai, L, Sun, J, Spanos, C, Chen, Z.A, Barbon, M, Rappsilber, J, Stillman, B, Speck, C, Li, H.
登録日2017-03-21
公開日2017-05-10
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Nat. Struct. Mol. Biol., 24, 2017
5XF8
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BU of 5xf8 by Molmil
Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state
分子名称: Cell division cycle protein CDT1, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ...
著者Zhai, Y, Cheng, E, Wu, H, Li, N, Yung, P.Y, Gao, N, Tye, B.K.
登録日2017-04-09
公開日2017-05-03
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer
Nat. Struct. Mol. Biol., 24, 2017
5U8T
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BU of 5u8t by Molmil
Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications
分子名称: Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ...
著者Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E.
登録日2016-12-15
公開日2017-02-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U8S
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BU of 5u8s by Molmil
Structure of eukaryotic CMG helicase at a replication fork
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (26-MER), ...
著者Li, H, Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, O'Donnell, M.E.
登録日2016-12-14
公開日2017-01-25
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (6.101 Å)
主引用文献Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3JC7
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BU of 3jc7 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JC5
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BU of 3jc5 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JC6
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BU of 3jc6 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JA8
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BU of 3ja8 by Molmil
Cryo-EM structure of the MCM2-7 double hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
著者Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
登録日2015-05-09
公開日2015-08-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
4R7Z
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BU of 4r7z by Molmil
PfMCM-AAA double-octamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 21, MAGNESIUM ION
著者Miller, J.M, Arachea, B.T, Epling, L.B, Enemark, E.J.
登録日2014-08-28
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Analysis of the crystal structure of an active MCM hexamer.
Elife, 3, 2014
4R7Y
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BU of 4r7y by Molmil
Crystal structure of an active MCM hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Miller, J.M, Arachea, B.T, Epling, L.B, Enemark, E.J.
登録日2014-08-28
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Analysis of the crystal structure of an active MCM hexamer.
Elife, 3, 2014
4FDG
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BU of 4fdg by Molmil
Crystal Structure of an Archaeal MCM Filament
分子名称: Minichromosome maintenance protein MCM, ZINC ION
著者Slaymaker, I.M, Fu, Y, Brewster, A.B, Chen, X.S.
登録日2012-05-28
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.
Nucleic Acids Res., 41, 2013

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