PDB: 264 件ウェブページステータス検索Chemie searchBIRD

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4XVI	Binary complex of human polymerase nu and DNA with the finger domain ajar 分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4XVK	Binary complex of human polymerase nu and DNA with the finger domain closed 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4XVL	Binary complex of human polymerase nu and DNA with the finger domain open 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4YFU	Crystal structure of open Bacillus fragment DNA polymerase bound to DNA and dTTP 分子名称: DNA polymerase, Primer DNA, SULFATE ION, ... 著者 Wu, E.Y. 登録日 2015-02-25 公開日 2015-07-22 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Closing Mechanism of DNA Polymerase I at Atomic Resolution. Structure, 23, 2015
5DKU	C-terminal His tagged apPOL exonuclease mutant 分子名称: MAGNESIUM ION, Prex DNA polymerase 著者 Milton, M.E, Honzatko, R.B, Choe, J.Y, Nelson, S.W. 登録日 2015-09-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase. J.Mol.Biol., 428, 2016
5DKT	N-terminal His tagged apPOL exonuclease mutant 分子名称: Prex DNA polymerase, SODIUM ION, SULFATE ION 著者 Milton, M.E, Honzatko, R.B, Choe, J.Y, Nelson, S.W. 登録日 2015-09-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase. J.Mol.Biol., 428, 2016
5E41	Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(N-(10-hydroxydecanoyl)-aminopentenyl)-2'-deoxyuridine-triphosphate 分子名称: 2'-deoxy-5-{(1E)-5-[(10-hydroxydecanoyl)amino]pent-1-en-1-yl}uridine 5'-(tetrahydrogen triphosphate), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Hottin, A, Betz, K, Marx, A. 登録日 2015-10-05 公開日 2016-12-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides. Chemistry, 23, 2017
5IKN	Crystal Structure of the T7 Replisome in the Absence of DNA 分子名称: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1 著者 Wallen, J.R, Ellenberger, T. 登録日 2016-03-03 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.802 Å) 主引用文献 Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome. Structure, 25, 2017
5SZT	Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentenyl)-7-deaza-2'-dATP 分子名称: 7-(N-(10-hydroxydecanoyl)-aminopentenyl)-7-deaza-2'-dATP, ACETATE ION, DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Hottin, A, Betz, K, Marx, A. 登録日 2016-08-15 公開日 2016-12-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides. Chemistry, 23, 2017
5NKL	Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a closed ternary complex with the artificial base pair dDs-dPxTP 分子名称: ACETATE ION, DNA (5'-D(*AP*AP*AP*(DNU)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Betz, K, Marx, A, Diederichs, K, Hirao, I, Kimoto, M. 登録日 2017-03-31 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair. Angew. Chem. Int. Ed. Engl., 56, 2017
5O7T	Crystal structure of KlenTaq mutant M747K in a closed ternary complex with a dG:dCTP base pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase I, thermostable, ... 著者 Betz, K, Diederichs, K, Marx, A. 登録日 2017-06-09 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase. Chem. Commun. (Camb.), 53, 2017
5W6Q	Structural basis for recognition of artificial DNA by an evolved KlenTaq variant 分子名称: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA polymerase I, ... 著者 Singh, I, Georgiadis, M.M. 登録日 2017-06-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46, 2018
5W6K	Structure of mutant Taq Polymerase incorporating unnatural base pairs Z:P 分子名称: (1R)-1-[6-amino-5-(dihydroxyamino)-2-hydroxypyridin-3-yl]-1,4-anhydro-2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-erythro-pentitol, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(P*(1WA)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Singh, I, Georgiadis, M.M. 登録日 2017-06-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.339 Å) 主引用文献 Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46, 2018
5OXJ	Crystal structure of KlenTaq mutant M747K in a closed ternary complex with a O6-MeG:BenziTP base pair 分子名称: ACETATE ION, DNA polymerase I, thermostable, ... 著者 Betz, K, Diederichs, K, Marx, A. 登録日 2017-09-06 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase. Chem. Commun. (Camb.), 53, 2017
5YTE	Large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with with natural dT:dATP base pair 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5YTD	large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the natural base pair 5fC:dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(5FC)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5YTC	Large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the unnatural base M-fC pair with dATP in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(92F)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC)P*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5YTF	Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5YTH	Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dG 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5YTG	Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base I-fC pair with dA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(94O)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
6FBI	KlenTaq DNA polymerase in a closed, ternary complex with dGpNHpp bound in the active site 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FBE	KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the third primer nucleotide. 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*GP*GP*TP*GP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.589 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FBF	KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the fourth primer nucleotide. 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*CP*GP*GP*TP*GP*CP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*GP*CP*AP*(OH3)P*CP*GP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FBC	KlenTaq DNA polymerase processing a modified primer - bearing the modification at the 3'-terminus of the primer. 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FBD	KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the second primer nucleotide. 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*AP*(OH3)P*C)-3'), DNA (5'-D(P*AP*AP*AP*CP*GP*GP*TP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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