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7V3M	Deactive state complex I from rotenone-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-10 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V33	Active state complex I from rotenone-NADH dataset Descriptor: (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-10 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V32	Deactive state complex I from rotenone dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-10 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V31	Active state complex I from rotenone dataset Descriptor: (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-10 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V30	Deactive state complex I from Q1-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-10 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2R	Active state complex I from Q1-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-09 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2K	Deactive state complex I from DQ-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-09 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2H	Active state complex I from DQ-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-09 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2F	Deactive state complex I from Q10-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-09 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2E	Active state complex I from Q10-NADH dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-08 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2D	Deactive state complex I from Q10 dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-08 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7V2C	Active state complex I from Q10 dataset Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Gu, J.K, Yang, M.J. Deposit date: 2021-08-08 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7TGH	Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... Authors: Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A. Deposit date: 2022-01-07 Release date: 2022-04-06 Last modified: 2022-07-20 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism. Science, 376, 2022
7T30	Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN/NAD(H) bound state Descriptor: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... Authors: Feng, X, Li, H. Deposit date: 2021-12-06 Release date: 2022-03-16 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase. Sci Adv, 8, 2022
7T2R	Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN-free apo state Descriptor: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... Authors: Feng, X, Li, H. Deposit date: 2021-12-06 Release date: 2022-03-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase. Sci Adv, 8, 2022
7R4G	Bovine complex I in the presence of IM1761092, slack class ii (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R4F	Bovine complex I in the presence of IM1761092, slack class i (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R4D	Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R4C	Bovine complex I in the presence of IM1761092, deactive class v (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R48	Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R47	Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R46	Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R45	Bovine complex I in the presence of IM1761092, deactive class i (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R44	Bovine complex I in the presence of IM1761092, active class iv (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R43	Bovine complex I in the presence of IM1761092, active class iii (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023

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