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1WDK
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fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)
分子名称: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
6L3P
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BU of 6l3p by Molmil
Crystal strcuture of Feruloyl-CoA hydratase lyase(FCHL) complexed with CoA
分子名称: COENZYME A, GLYCEROL, Hydroxycinnamoyl-CoA hydratase-lyase
著者Seok, J, Seo, H, Kim, K.-J.
登録日2019-10-14
公開日2020-10-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Kinetic and structural analysis for bioproduction of vanillin by feruloyl-CoA hydratase/lyase from Pseudomonas putida KT2440
to be published
2ZQR
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BU of 2zqr by Molmil
Crystal structure of AUH without RNA
分子名称: Methylglutaconyl-CoA hydratase
著者Kurimoto, K, Kuwasako, K, Muto, Y, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-08-16
公開日2009-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献AU-rich RNA-binding induces changes in the quaternary structure of AUH
Proteins, 75, 2009
6J1G
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BU of 6j1g by Molmil
Crystal structure of HypX from Aquifex aeolicus, R9A-Q15A-R131A-R542A variant
分子名称: COENZYME A, GLYCEROL, Hydrogenase regulation HoxX
著者Muraki, N, Aono, S.
登録日2018-12-28
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of HypX responsible for CO biosynthesis in the maturation of NiFe-hydrogenase.
Commun Biol, 2, 2019
1HNO
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CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM SACCHAROMYCES CEREVISIAE
分子名称: 1,2-ETHANEDIOL, D3,D2-ENOYL COA ISOMERASE ECI1
著者Mursula, A.M, van Aalten, D.M.F, Hiltunen, J.K, Wierenga, R.K.
登録日2000-12-08
公開日2001-06-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.
J.Mol.Biol., 309, 2001
3ZW8
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Crystal Structure Of Rat Peroxisomal Multifunctional Enzyme Type 1 (rpMFE1) In Apo Form
分子名称: GLYCEROL, PEROXISOMAL BIFUNCTIONAL ENZYME, SULFATE ION
著者Kasaragod, P, Schmitz, W, Hiltunen, J.K, Wierenga, R.K.
登録日2011-07-28
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Isomerase and Hydratase Reaction Mechanism of the Crotonase Active Site of the Multifunctional Enzyme (Type-1), as Deduced from Structures of Complexes with 3S-Hydroxy- Acyl-Coa.
FEBS J., 280, 2013
3M6M
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Crystal structure of RpfF complexed with REC domain of RpfC
分子名称: 1,2-ETHANEDIOL, IODIDE ION, MAGNESIUM ION, ...
著者Cheng, Z, Lim, S.C, Qamra, R, Song, H.
登録日2010-03-16
公開日2010-09-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of the Sensor-Synthase Interaction in Autoinduction of the Quorum Sensing Signal DSF Biosynthesis
Structure, 18, 2010
4LK5
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Crystal structure of a enoyl-CoA hydratase from Mycobacterium avium subsp. paratuberculosis K-10
分子名称: enoyl-CoA hydratase
著者Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-07-06
公開日2013-07-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a enoyl-CoA hydratase from Mycobacterium avium subsp. paratuberculosis K-10
To be Published
4B3J
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BU of 4b3j by Molmil
Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA bound at the hydratase and thiolase active sites
分子名称: ADENOSINE-5'-DIPHOSPHATE, COENZYME A, FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB, ...
著者Venkatesan, R, Wierenga, R.K.
登録日2012-07-24
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Mycobacterial Beta-Oxidation Trifunctional Enzyme Reveals its Altered Assembly and Putative Substrate Channeling Pathway.
Acs Chem.Biol., 8, 2013
2WTB
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Arabidopsis thaliana multifuctional protein, MFP2
分子名称: FATTY ACID MULTIFUNCTIONAL PROTEIN (ATMFP2)
著者Arent, S, Pye, V.E, Christensen, C.E, Norgaard, A, Henriksen, A.
登録日2009-09-15
公開日2010-05-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Multi-Functional Protein in Peroxisomal Beta-Oxidation. Structure and Substrate Specificity of the Arabidopsis Thaliana Protein, Mfp2
J.Biol.Chem., 285, 2010
4HC8
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CRYSTAL STRUCTURE OF PROBABLE ENOYL-CoA HYDRATASE ECHA3 (Rv0632c, NYSGRC-019494) from Mycobacterium Tuberculosis H37Rv
分子名称: 1,2-ETHANEDIOL, Enoyl-CoA hydratase/isomerase family protein, SULFATE ION
著者Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-09-28
公開日2012-10-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of probable enoyl-CoA hydratase ECHA3 (Rv0632c, NYSGRC-019494) from Mycobacterium Tuberculosis H37Rv
To be Published
8OPW
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BU of 8opw by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Caffeine (Fragment-B-51)
分子名称: 3-hydroxyacyl-CoA dehydrogenase, CAFFEINE, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-10
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
2HW5
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BU of 2hw5 by Molmil
The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
分子名称: CROTONYL COENZYME A, Enoyl-CoA hydratase, MAGNESIUM ION
著者Turnbull, A.P, Salah, E, Niesen, F, Debreczeni, J, Ugochukwu, E, Pike, A.C.W, Kavanagh, K, Gileadi, O, Gorrec, F, Umeano, C, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-07-31
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
To be Published
6SLA
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BU of 6sla by Molmil
Crystal structure of isomerase PaaG mutant - D136N with Oxepin-CoA
分子名称: Enoyl-CoA hydratase/carnithine racemase, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 2-(2,5-dihydrooxepin-7-yl)ethanethioate
著者Saleem-Batcha, R, Spieker, M, Teufel, R.
登録日2019-08-19
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural and Mechanistic Basis of an Oxepin-CoA Forming Isomerase in Bacterial Primary and Secondary Metabolism.
Acs Chem.Biol., 14, 2019
4FZW
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Crystal Structure of the PaaF-PaaG Hydratase-Isomerase Complex from E.coli
分子名称: 1,2-epoxyphenylacetyl-CoA isomerase, 2,3-dehydroadipyl-CoA hydratase, GLYCEROL
著者Grishin, A.M, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2012-07-08
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Protein-Protein Interactions in the beta-Oxidation Part of the Phenylacetate Utilization Pathway. Crystal Structure of the PaaF-PaaG Hydratase-Isomerase Complex
J.Biol.Chem., 287, 2012
4ELW
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BU of 4elw by Molmil
Structure of E. coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with nitrate
分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ...
著者Sun, Y.R, Song, H.G, Li, J, Jiang, M, Li, Y, Zhou, J.H, Guo, Z.H.
登録日2012-04-11
公開日2012-06-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
4YLH
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BU of 4ylh by Molmil
Crystal structure of DpgC with bound substrate analog and Xe on oxygen diffusion pathway
分子名称: DpgC, XENON, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Li, K, Di Russo, N.V, Condurso, H.L, Roitberg, A.E, Bruner, S.D.
登録日2015-03-05
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Oxygen diffusion pathways in a cofactor-independent dioxygenase.
Chem Sci, 6, 2015
8OQQ
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-79
分子名称: 2-fluoranyl-5-sulfo-benzoic acid, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
8OQO
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-49
分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
5DU6
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Crystal structure of M. tuberculosis EchA6 bound to ligand GSK059A.
分子名称: (5R,7R)-5-(4-ethylphenyl)-N-(4-fluorobenzyl)-7-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, Probable enoyl-CoA hydratase echA6
著者Cox, J.A.G, Besra, G.S, Futterer, K.
登録日2015-09-18
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria.
Nat Microbiol, 1, 2016
8OQT
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-91
分子名称: 3-hydroxyacyl-CoA dehydrogenase, 4-bromanylbenzenesulfonic acid, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
4B3I
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BU of 4b3i by Molmil
Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA bound at the hydratase active sites
分子名称: ADENOSINE-5'-DIPHOSPHATE, COENZYME A, FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB, ...
著者Venkatesan, R, Wierenga, R.K.
登録日2012-07-24
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structure of Mycobacterial Beta-Oxidation Trifunctional Enzyme Reveals its Altered Assembly and Putative Substrate Channeling Pathway.
Acs Chem.Biol., 8, 2013
4U18
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Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase (ISO-ECI2)
分子名称: CHLORIDE ION, Enoyl-CoA delta isomerase 2, mitochondrial, ...
著者Onwukwe, G.U, Koski, M.K, Wierenga, R.K.
登録日2014-07-15
公開日2014-12-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10.
Febs J., 282, 2015
5KAJ
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BU of 5kaj by Molmil
Crystal structure of a dioxygenase in the Crotonase superfamily in P21, A319C mutant
分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[(~{E})-2-[3,5-bis(oxidanyl)phenyl]-1-oxidanyl-ethenyl]sulfanylethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate
著者Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D.
登録日2016-06-01
公開日2017-06-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.681 Å)
主引用文献Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol, 73, 2017
6LVP
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Enoyl-CoA hydratase (HyECH) from Hymenobacter sp. PAMC 26628
分子名称: Enoyl-CoA hydratase
著者Hwang, J.S, Jung, C, Lee, C.W, Lee, J.H.
登録日2020-02-04
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural and sequence comparisons of bacterial enoyl-CoA isomerase and enoyl-CoA hydratase.
J.Microbiol, 58, 2020

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