6SLA

Crystal structure of isomerase PaaG mutant - D136N with Oxepin-CoA

This is a non-PDB format compatible entry.

Summary for 6SLA

• Entry DOI: 10.2210/pdb6sla/pdb
• Related: 6SL9
• Descriptor: Enoyl-CoA hydratase/carnithine racemase, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 2-(2,5-dihydrooxepin-7-yl)ethanethioate (3 entities in total)
• Functional Keywords: phenylacetic acid catabolism, isomerase, tropodithietic acid, crotonase
• Biological source: Thermus thermophilus JL-18
• Total number of polymer chains: 6
• Total formula weight: 170877.34

Authors

Saleem-Batcha, R.,Spieker, M.,Teufel, R. (deposition date: 2019-08-19, release date: 2019-12-11, Last modification date: 2024-01-24)

• Primary citation: Spieker, M.,Saleem-Batcha, R.,Teufel, R.; Structural and Mechanistic Basis of an Oxepin-CoA Forming Isomerase in Bacterial Primary and Secondary Metabolism.; Acs Chem.Biol., 14:2876-2886, 2019; PubMed: 31689071; DOI: 10.1021/acschembio.9b00742

Experimental method

X-RAY DIFFRACTION (2.55 Å)