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2UZF
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Crystal structure of Staphylococcus aureus 1,4-dihydroxy-2-naphthoyl CoA synthase (MenB) in complex with acetoacetyl CoA
分子名称: ACETOACETYL-COENZYME A, NAPHTHOATE SYNTHASE
著者Ulaganathan, V, Buetow, L, Hunter, W.N.
登録日2007-04-27
公開日2007-11-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Staphylococcus Aureus1,4-Dihydroxy-2-Naphthoyl-Coa Synthase (Menb) in Complex with Acetoacetyl-Coa.
Acta Crystallogr.,Sect.F, 63, 2007
6TNM
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BU of 6tnm by Molmil
E. coli aerobic trifunctional enzyme subunit-alpha
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Fatty acid oxidation complex subunit alpha, GLYCEROL, ...
著者Sah-Teli, S.K, Hynonen, M.J, Wierenga, R.K, Venkatesan, R.
登録日2019-12-09
公開日2020-03-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Insights into the stability and substrate specificity of the E. coli aerobic beta-oxidation trifunctional enzyme complex.
J.Struct.Biol., 210, 2020
8SK6
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human liver mitochondrial Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase
分子名称: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
著者Zhang, Z, Tringides, M.
登録日2023-04-18
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Mol.Cell Proteomics, 22, 2023
4ZDD
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Structure of yeast D3,D2-enoyl-CoA isomerase bound to sulphate ion
分子名称: 3,2-trans-enoyl-CoA isomerase, SULFATE ION
著者Onwukwe, G.U, Koski, M.K, Wierenga, R.K.
登録日2015-04-17
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of yeast peroxisomal Delta (3), Delta (2)-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues: the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole.
Acta Crystallogr.,Sect.D, 71, 2015
7ZQ7
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Structure of RpF-1
分子名称: Crotonase/enoyl-CoA hydratase family protein
著者Sanchez-Alba, L, Reverter, D, Conchillo, O, Yero, D, Daura, X, Gibert, I.
登録日2022-04-29
公開日2023-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of RpF-1
To Be Published
2PG8
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Crystal structure of R254K mutanat of DpgC with bound substrate analog
分子名称: DpgC, OXYGEN MOLECULE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Fielding, E.N.
登録日2007-04-09
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Substrate Recognition and Catalysis by the Cofactor-Independent Dioxygenase DpgC.
Biochemistry, 46, 2007
7O1G
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A-H462A, beta-C92A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, Putative acyltransferase Rv0859, SULFATE ION
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
8OPU
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Sulfamethoxazole (Fragment-B-E1)
分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-10
公開日2024-01-24
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
3ZWB
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1 (RPMFE1) COMPLEXED WITH 2TRANS-HEXENOYL-COA
分子名称: (2E)-Hexenoyl-CoA, GLYCEROL, PEROXISOMAL BIFUNCTIONAL ENZYME, ...
著者Kasaragod, P, Schmitz, W, Hiltunen, J.K, Wierenga, R.K.
登録日2011-07-28
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Isomerase and Hydratase Reaction Mechanism of the Crotonase Active Site of the Multifunctional Enzyme (Type-1), as Deduced from Structures of Complexes with 3S-Hydroxy- Acyl-Coa.
FEBS J., 280, 2013
2A81
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carboxymethylproline synthase (CarB) from pectobacterium carotovora, complexed with acetyl CoA and bicine
分子名称: ACETYL COENZYME *A, BICINE, CarB
著者Sleeman, M.C, Sorensen, J.L, Batchelar, E.T, McDonough, M.A, Schofield, C.J.
登録日2005-07-07
公開日2005-08-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural and Mechanistic Studies on Carboxymethylproline Synthase (CarB), a Unique Member of the Crotonase Superfamily Catalyzing the First Step in Carbapenem Biosynthesis.
J.Biol.Chem., 280, 2005
8OQM
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BU of 8oqm by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-10
分子名称: 3-hydroxyacyl-CoA dehydrogenase, 6-azanyl-4-oxidanyl-naphthalene-2-sulfonic acid, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
1K39
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BU of 1k39 by Molmil
The structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COA
分子名称: OCTANOYL-COENZYME A, PHOSPHATE ION, d3,d2-enoyl CoA isomerase ECI1
著者Mursula, A.M, Geerlof, A, Hiltunen, J.K, Wierenga, R.K.
登録日2001-10-02
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献

2D3T
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BU of 2d3t by Molmil
Fatty Acid beta-oxidation multienzyme complex from Pseudomonas Fragi, Form V
分子名称: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
著者Tsuchiya, D, Shimizu, N, Ishikawa, M, Suzuki, Y, Morikawa, K.
登録日2005-10-01
公開日2006-02-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Ligand-Induced Domain Rearrangement of Fatty Acid beta-Oxidation Multienzyme Complex
Structure, 14, 2006
1WDL
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BU of 1wdl by Molmil
fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4)
分子名称: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
8BNU
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Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex
分子名称: 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha
著者Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R.
登録日2022-11-14
公開日2023-05-17
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
6DV2
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Crystal Structure of Human Mitochondrial Trifunctional Protein
分子名称: Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
著者Fu, Z, Xia, C, Battaile, K.P, Kim, J.P.
登録日2018-06-22
公開日2018-09-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Crystal structure of human mitochondrial trifunctional protein, a fatty acid beta-oxidation metabolon.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1WDM
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BU of 1wdm by Molmil
fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3)
分子名称: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
8BRJ
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BU of 8brj by Molmil
Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex
分子名称: 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha
著者Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R.
登録日2022-11-23
公開日2023-05-17
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (4.08 Å)
主引用文献Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
5ZQZ
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Structure of human mitochondrial trifunctional protein, tetramer
分子名称: Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
著者Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J.
登録日2018-04-20
公開日2018-06-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8UJA
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T33-fn10 - Designed Tetrahedral Protein Cage Using Fragment-based Hydrogen Bond Networks
分子名称: T33-fn10: engineered DrsE like sulfur reductase, T33-fn10: engineered enoyl-CoA hydratase/isomerase
著者Meador, K, Sawaya, M.R, Yeates, T.O.
登録日2023-10-11
公開日2024-03-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献A suite of designed protein cages using machine learning and protein fragment-based protocols.
Structure, 2024
5ZRV
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Structure of human mitochondrial trifunctional protein, octamer
分子名称: Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
著者Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J.
登録日2018-04-25
公開日2018-06-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8BNR
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Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex
分子名称: 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha
著者Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R.
登録日2022-11-14
公開日2023-05-17
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (10.3 Å)
主引用文献Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023

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