1IV5
| New Crystal Form of Human CD81 Large Extracellular Loop. | Descriptor: | CD81 antigen | Authors: | Kitadokoro, K, Bolognesi, M, Grandi, G, Marco, P, Galli, G, Petracca, R, Fabiana, F. | Deposit date: | 2002-03-14 | Release date: | 2003-01-28 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Subunit Association and Conformational Flexibility in the Head-subdomain of Human CD81 Large Extracellular Loop. Biol.Chem., 383, 2002
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2M7Z
| Structure of SmTSP2EC2 | Descriptor: | CD63-like protein Sm-TSP-2 | Authors: | Mulvenna, J, Jia, X. | Deposit date: | 2013-05-02 | Release date: | 2014-01-22 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Solution structure, membrane interactions, and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni J.Biol.Chem., 289, 2014
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6K4J
| Crystal Structure of the the CD9 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CD9 antigen, NICKEL (II) ION, ... | Authors: | Umeda, R, Nishizawa, T, Sato, K, Nureki, O. | Deposit date: | 2019-05-24 | Release date: | 2020-05-13 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Structural insights into tetraspanin CD9 function. Nat Commun, 11, 2020
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7ZW1
| Human PRPH2-ROM1 hetero-dimer | Descriptor: | Nanobody, Peripherin-2, Rod outer segment membrane protein 1 | Authors: | El Mazouni, D, Gros, P. | Deposit date: | 2022-05-17 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structures of peripherin-2 and ROM1 suggest multiple roles in photoreceptor membrane morphogenesis. Sci Adv, 8, 2022
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1G8Q
| CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS | Descriptor: | CD81 ANTIGEN, EXTRACELLULAR DOMAIN | Authors: | Kitadokoro, K, Bolognesi, M, Bordo, D, Grandi, G, Galli, G, Petracca, R, Falugi, F. | Deposit date: | 2000-11-20 | Release date: | 2001-02-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs. EMBO J., 20, 2001
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5TCX
| Crystal structure of human tetraspanin CD81 | Descriptor: | CD81 antigen, CHOLESTEROL | Authors: | Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C. | Deposit date: | 2016-09-16 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.955 Å) | Cite: | Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket. Cell, 167, 2016
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6U9S
| Crystal structure of human CD81 large extracellular loop in complex with 5A6 Fab | Descriptor: | 5A6 FAB Heavy Chain, 5A6 FAB Light Chain, CD81 antigen, ... | Authors: | Susa, K.J, Seegar, T.C.M, Blacklow, S.C.B, Kruse, A.C. | Deposit date: | 2019-09-09 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking. Elife, 9, 2020
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7JIC
| Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment | Descriptor: | B-lymphocyte antigen CD19, CD81 antigen, Coltuximab Heavy Chain, ... | Authors: | Susa, K.J, Rawson, S, Kruse, A.C, Blacklow, S.C. | Deposit date: | 2020-07-23 | Release date: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81 Science, 371, 2021
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6Z1V
| Structure of the EC2 domain of CD9 in complex with nanobody 4E8 | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CD9 antigen, ... | Authors: | Oosterheert, W, Pearce, N.M, Gros, P. | Deposit date: | 2020-05-14 | Release date: | 2020-09-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life Sci Alliance, 3, 2020
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6Z20
| Structure of the EC2 domain of CD9 in complex with nanobody 4C8 | Descriptor: | CD9 antigen, CHLORIDE ION, GLYCEROL, ... | Authors: | Oosterheert, W, Manshande, J, Pearce, N.M, Lutz, M, Gros, P. | Deposit date: | 2020-05-14 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life Sci Alliance, 3, 2020
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6RLO
| Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | Descriptor: | AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... | Authors: | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | Deposit date: | 2019-05-02 | Release date: | 2021-05-12 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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7RDB
| Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) | Descriptor: | Tetraspanin-15 | Authors: | Lipper, C.H, Gabriel, K.H, Seegar, T.C.M, Durr, K.L, Tomlinson, M.G, Blacklow, S.C. | Deposit date: | 2021-07-09 | Release date: | 2021-11-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site. Structure, 30, 2022
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7RD5
| Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab | Descriptor: | 1C12 Fab Heavy Chain, 1C12 Fab Light Chain, Tetraspanin-15 | Authors: | Lipper, C.H, Gabriel, K.H, Seegar, T.C.M, Durr, K.L, Tomlinson, M.G, Blacklow, S.C. | Deposit date: | 2021-07-09 | Release date: | 2021-11-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site. Structure, 30, 2022
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5DFV
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5DFW
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6RLR
| Crystal structure of CD9 large extracellular loop | Descriptor: | CD9 antigen | Authors: | Neviani, V, Kroon-Batenburg, L, Lutz, M, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | Deposit date: | 2019-05-02 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life Sci Alliance, 3, 2020
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7MWS
| Crystal structure of tamarin CD81 large extracellular loop | Descriptor: | CD81 protein, GLYCEROL, TETRAETHYLENE GLYCOL | Authors: | Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. | Deposit date: | 2021-05-17 | Release date: | 2021-09-15 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into hepatitis C virus receptor binding and entry. Nature, 598, 2021
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3X0F
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3X0E
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3X0G
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6EJG
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6EJM
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6EK2
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5M2C
| Structural tuning of CD81LEL (space group P32 1 2) | Descriptor: | CD81 antigen, PHOSPHATE ION | Authors: | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | Deposit date: | 2016-10-12 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.961 Å) | Cite: | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop. Structure, 25, 2017
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5M33
| Structural tuning of CD81LEL (space group P21) | Descriptor: | 1,2-ETHANEDIOL, CD81 antigen | Authors: | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | Deposit date: | 2016-10-14 | Release date: | 2016-12-14 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop. Structure, 25, 2017
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