PDB: 112 件ウェブページステータス検索Chemie searchBIRD

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1BNC	THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE 分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION 著者 Waldrop, G, Rayment, I, Holden, H.M. 登録日 1994-07-06 公開日 1995-08-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase. Biochemistry, 33, 1994
1DV2	The structure of biotin carboxylase, mutant E288K, complexed with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE 著者 Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. 登録日 2000-01-19 公開日 2000-06-09 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
1DV1	STRUCTURE OF BIOTIN CARBOXYLASE (APO) 分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION 著者 Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. 登録日 2000-01-19 公開日 2000-06-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
1ULZ	Crystal structure of the biotin carboxylase subunit of pyruvate carboxylase 分子名称: pyruvate carboxylase n-terminal domain 著者 Kondo, S, Nakajima, Y, Sugio, S, Yong-Biao, J, Sueda, S, Kondo, H. 登録日 2003-09-18 公開日 2004-03-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution. Acta Crystallogr.,Sect.D, 60, 2004
1W93	Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae 分子名称: ACETYL-COENZYME A CARBOXYLASE 著者 Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. 登録日 2004-10-05 公開日 2005-01-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
1W96	Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A 分子名称: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A 著者 Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. 登録日 2004-10-06 公開日 2005-01-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
2GPW	Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli. 分子名称: Biotin carboxylase 著者 Shen, Y, Chou, C.Y, Chang, G.G, Tong, L. 登録日 2006-04-18 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006
2GPS	Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli. 分子名称: Biotin carboxylase 著者 Shen, Y, Chou, C.Y, Chang, G.G, Tong, L. 登録日 2006-04-18 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006
2HJW	Crystal Structure of the BC domain of ACC2 分子名称: Acetyl-CoA carboxylase 2 著者 Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. 登録日 2006-07-02 公開日 2007-07-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2. Proteins, 70, 2008
2QF7	Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli 分子名称: CHLORIDE ION, COENZYME A, FORMIC ACID, ... 著者 St Maurice, M, Surinya, K.H, Rayment, I. 登録日 2007-06-27 公開日 2007-09-04 最終更新日 2012-02-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme Science, 317, 2007
2DZD	Crystal structure of the biotin carboxylase domain of pyruvate carboxylase 分子名称: pyruvate carboxylase 著者 Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H. 登録日 2006-09-27 公開日 2007-09-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans ACTA CRYSTALLOGR.,SECT.D, 63, 2007
3BG5	Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Xiang, S, Tong, L. 登録日 2007-11-26 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol., 15, 2008
2VQD	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP 分子名称: BIOTIN CARBOXYLASE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Mochalkin, I. 登録日 2008-03-13 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2VPQ	Crystal structure of biotin carboxylase from S. aureus complexed with AMPPNP 分子名称: ACETYL-COA CARBOXYLASE, CHLORIDE ION, MAGNESIUM ION, ... 著者 Mochalkin, I. 登録日 2008-03-03 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2C00	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form 分子名称: BIOTIN CARBOXYLASE, SULFATE ION 著者 Mochalkin, I. 登録日 2008-03-21 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2J9G	Crystal structure of Biotin carboxylase from E. coli in complex with AMPPNP and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, BIOTIN CARBOXYLASE, MAGNESIUM ION, ... 著者 Mochalkin, I. 登録日 2008-03-21 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2VR1	Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P. 分子名称: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER 著者 Mochalkin, I, Waldrop, G.L. 登録日 2008-03-24 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2V59	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2 分子名称: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V58	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 分子名称: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 分子名称: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
3G8C	Crystal Structure of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg Ion 分子名称: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, BIOTIN, ... 著者 Chou, C.Y, Yu, L.P, Tong, L. 登録日 2009-02-12 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. J.Biol.Chem., 284, 2009
3G8D	Crystal structure of the biotin carboxylase subunit, E296A mutant, of acetyl-COA carboxylase from Escherichia coli 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION, ... 著者 Chou, C.Y, Yu, L.P, Tong, L. 登録日 2009-02-12 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. J.Biol.Chem., 284, 2009
3GID	The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) in complex with Soraphen A 分子名称: Acetyl-CoA carboxylase 2, SORAPHEN A 著者 Price, A, Kulathila, R. 登録日 2009-03-05 公開日 2009-03-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase. Bioorg.Med.Chem.Lett., 19, 2009
3GLK	The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) 分子名称: Acetyl-CoA carboxylase 2 著者 Price, A, Kulathila, R. 登録日 2009-03-12 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase. Bioorg.Med.Chem.Lett., 19, 2009
2W6O	Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment 分子名称: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009

 

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