Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2PIZ
DownloadVisualize
BU of 2piz by Molmil
CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B 2-(3-Guanidino-phenyl)-3-[hydroxy-(3-phenyl-propyl)-phosphinoyl]-propionic acid COMPLEX
Descriptor: (2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID, Carboxypeptidase B, ZINC ION
Authors:Adler, M, Whitlow, M.
Deposit date:2007-04-15
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Acta Crystallogr.,Sect.D, 64, 2008
2PIY
DownloadVisualize
BU of 2piy by Molmil
CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B (S)-2-(3-Aminomethyl-phenyl)-3-{hydroxy-[(R)-2-methyl-1-(3-phenyl-propane-1-sulfonylamino)-propyl]-phosphinoyl}-propionic acid {ZK 528} COMPLEX
Descriptor: (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID, Carboxypeptidase B, ZINC ION
Authors:Adler, M, Whitlow, M.
Deposit date:2007-04-15
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Acta Crystallogr.,Sect.D, 64, 2008
2PCU
DownloadVisualize
BU of 2pcu by Molmil
Human carboxypeptidase A4 in complex with a cleaved hexapeptide.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC ACID, Carboxypeptidase A4, ...
Authors:Bayes, A, Fernandez, D, Sola, M, Marrero, A, Garcia-Pique, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X.
Deposit date:2007-03-30
Release date:2007-04-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.
Biochemistry, 46, 2007
2NSM
DownloadVisualize
BU of 2nsm by Molmil
Crystal structure of the human carboxypeptidase N (Kininase I) catalytic domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase N catalytic chain, SULFATE ION
Authors:Keil, C, Maskos, K, Than, M, Hoopes, J.T, Huber, R, Tan, F, Deddish, P.A, Erdoes, E.G, Skidgel, R.A, Bode, W.
Deposit date:2006-11-05
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
J.Mol.Biol., 366, 2007
2JEW
DownloadVisualize
BU of 2jew by Molmil
Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB
Descriptor: (2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]PENTANOIC ACID, CARBOXYPEPTIDASE B, ZINC ION
Authors:Brown, D.G, Moore, R.S.
Deposit date:2007-01-24
Release date:2007-11-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.
J. Med. Chem., 50, 2007
2CTC
DownloadVisualize
BU of 2ctc by Molmil
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
Descriptor: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CARBOXYPEPTIDASE A, ZINC ION
Authors:Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
Deposit date:1993-04-02
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2CTB
DownloadVisualize
BU of 2ctb by Molmil
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
Descriptor: CARBOXYPEPTIDASE A, ZINC ION
Authors:Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
Deposit date:1993-04-02
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2C1C
DownloadVisualize
BU of 2c1c by Molmil
Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors
Descriptor: CARBOXYPEPTIDASE B, YTTRIUM ION, ZINC ION
Authors:Bayes, A, Comellas-Bigler, M, Rodriguez de la Vega, M, Maskos, K, Bode, W, Aviles, F.X, Jongsma, M.A, Beekwilder, J, Vendrell, J.
Deposit date:2005-09-12
Release date:2005-10-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors.
Proc.Natl.Acad.Sci.USA, 102, 2005
2BOA
DownloadVisualize
BU of 2boa by Molmil
Human procarboxypeptidase A4.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE A4, ...
Authors:Garcia-Castellanos, R, Bonet-Figueredo, R, Pallares, I, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X.
Deposit date:2005-04-08
Release date:2005-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Detailed Molecular Comparison between the Inhibition Mode of A/B-Type Carboxypeptidases in the Zymogen State and by the Endogenous Inhibitor Latexin.
Cell.Mol.Life Sci., 62, 2005
2BO9
DownloadVisualize
BU of 2bo9 by Molmil
Human carboxypeptidase A4 in complex with human latexin.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ...
Authors:Pallares, I, Bonet, R, Garcia-Castellanos, R, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Rueth, F.X.
Deposit date:2005-04-08
Release date:2005-04-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Human Carboxypeptidase A4 with its Endogenous Protein Inhibitor, Latexin.
Proc.Natl.Acad.Sci.USA, 102, 2005
2ABZ
DownloadVisualize
BU of 2abz by Molmil
Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
Descriptor: Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L, Popowicz, G.M, Bronsoms, S, Aviles, F.X, Huber, R, Holak, T.A, Ventura, S.
Deposit date:2005-07-18
Release date:2006-01-31
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
1ZLI
DownloadVisualize
BU of 1zli by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B
Descriptor: Carboxypeptidase B, ZINC ION, carboxypeptidase inhibitor
Authors:Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZLH
DownloadVisualize
BU of 1zlh by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
Descriptor: Carboxypeptidase A1, ZINC ION, carboxypeptidase inhibitor
Authors:Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZG9
DownloadVisualize
BU of 1zg9 by Molmil
Crystal Structure of 5-{[amino(imino)methyl]amino}-2-(sulfanylmethyl)pentanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
Descriptor: 5-{[AMINO(IMINO)METHYL]AMINO}-2-(SULFANYLMETHYL)PENTANOIC ACID, ZINC ION, procarboxypeptidase B
Authors:Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG8
DownloadVisualize
BU of 1zg8 by Molmil
Crystal Structure of (R)-2-(3-{[amino(imino)methyl]amino}phenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
Descriptor: (2R)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B
Authors:Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG7
DownloadVisualize
BU of 1zg7 by Molmil
Crystal Structure of 2-(5-{[amino(imino)methyl]amino}-2-chlorophenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
Descriptor: 2-(5-{[AMINO(IMINO)METHYL]AMINO}-2-CHLOROPHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B
Authors:Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1Z5R
DownloadVisualize
BU of 1z5r by Molmil
Crystal Structure of Activated Porcine Pancreatic Carboxypeptidase B
Descriptor: ZINC ION, procarboxypeptidase B
Authors:Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
Deposit date:2005-03-18
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1YME
DownloadVisualize
BU of 1yme by Molmil
STRUCTURE OF CARBOXYPEPTIDASE
Descriptor: CARBOXYPEPTIDASE A ALPHA, ZINC ION
Authors:Greenblatt, H.M, Tucker, P.A, Shoham, G.
Deposit date:1996-07-15
Release date:1997-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
1UWY
DownloadVisualize
BU of 1uwy by Molmil
Crystal structure of human carboxypeptidase M
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE M, ZINC ION
Authors:Maskos, K, Reverter, D, Bode, W.
Deposit date:2004-02-17
Release date:2004-04-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Human Carboxypeptidase M, a Membrane-Bound Enzyme that Regulates Peptide Hormone Activity
J.Mol.Biol., 338, 2004
1QMU
DownloadVisualize
BU of 1qmu by Molmil
Duck carboxypeptidase D domain II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE GP180 RESIDUES 503-882, SULFATE ION, ...
Authors:Gomis-Rueth, F.X, Coll, M, Aviles, F.X, Vendrell, J, Fricker, L.D.
Deposit date:1999-10-06
Release date:2000-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Avian Carboxypeptidase D Domain II : A Prototype for the Regulatory Metallocarboxypeptidase Subfamily
Embo J., 18, 1999
1PYT
DownloadVisualize
BU of 1pyt by Molmil
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
Descriptor: CALCIUM ION, CHYMOTRYPSINOGEN C, PROCARBOXYPEPTIDASE A, ...
Authors:Gomis-Ruth, F.X, Gomez, M, Bode, W, Huber, R, Aviles, F.X.
Deposit date:1995-06-21
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995
1PCA
DownloadVisualize
BU of 1pca by Molmil
THREE DIMENSIONAL STRUCTURE OF PORCINE PANCREATIC PROCARBOXYPEPTIDASE A. A COMPARISON OF THE A AND B ZYMOGENS AND THEIR DETERMINANTS FOR INHIBITION AND ACTIVATION
Descriptor: CITRIC ACID, PROCARBOXYPEPTIDASE A PCPA, VALINE, ...
Authors:Guasch, A, Coll, M, Aviles, F.X, Huber, R.
Deposit date:1991-10-28
Release date:1993-10-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation.
J.Mol.Biol., 224, 1992
1OBR
DownloadVisualize
BU of 1obr by Molmil
CARBOXYPEPTIDASE T
Descriptor: CALCIUM ION, CARBOXYPEPTIDASE T, SULFATE ION, ...
Authors:Teplyakov, A, Polyakov, K, Obmolova, G, Osterman, A.
Deposit date:1996-06-22
Release date:1997-01-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris.
Eur.J.Biochem., 208, 1992
1NSA
DownloadVisualize
BU of 1nsa by Molmil
THREE-DIMENSIONAL STRUCTURE OF PORCINE PROCARBOXYPEPTIDASE B: A STRUCTURAL BASIS OF ITS INACTIVITY
Descriptor: BENZAMIDINE, PROCARBOXYPEPTIDASE B, ZINC ION
Authors:Huber, R.
Deposit date:1997-07-25
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity.
EMBO J., 10, 1991
1M4L
DownloadVisualize
BU of 1m4l by Molmil
STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION
Descriptor: CARBOXYPEPTIDASE A, ZINC ION
Authors:Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G.
Deposit date:2002-07-03
Release date:2003-01-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Refined structure of bovine carboxypeptidase A at 1.25 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003

220113

數據於2024-05-22公開中

PDB statisticsPDBj update infoContact PDBjnumon