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2PIY

CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B (S)-2-(3-Aminomethyl-phenyl)-3-{hydroxy-[(R)-2-methyl-1-(3-phenyl-propane-1-sulfonylamino)-propyl]-phosphinoyl}-propionic acid {ZK 528} COMPLEX

Summary for 2PIY
Entry DOI10.2210/pdb2piy/pdb
Related1Z5R 1ZG7 1ZG8 1ZG9 2PIZ 2PJ0 2PJ1 2PJ2 2PJ3 2PJ4 2PJ5 2PJ6 2PJ7 2PJ8 2PJ9 2PJA 2PJB 2PJC
DescriptorCarboxypeptidase B, ZINC ION, (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID, ... (4 entities in total)
Functional Keywordscarboxypeptidase b, exopeptidase, phosphinate based inhibitor, hydrolase
Biological sourceSus scrofa (pig)
Cellular locationSecreted: P09955
Total number of polymer chains3
Total formula weight105905.47
Authors
Adler, M.,Whitlow, M. (deposition date: 2007-04-15, release date: 2008-01-22, Last modification date: 2023-08-30)
Primary citationAdler, M.,Buckman, B.,Bryant, J.,Chang, Z.,Chu, K.,Emayan, K.,Hrvatin, P.,Islam, I.,Morser, J.,Sukovich, D.,West, C.,Yuan, S.,Whitlow, M.
Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Acta Crystallogr.,Sect.D, 64:149-157, 2008
Cited by
PubMed: 18219114
DOI: 10.1107/S0907444907057228
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.43 Å)
Structure validation

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