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5FEG
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BU of 5feg by Molmil
Crystal structure of the dimeric allergen profilin (Hev b 8)
Descriptor: Profilin-2
Authors:Mares-Mejia, I, Rodriguez-Romero, A.
Deposit date:2015-12-17
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
Sci Rep, 6, 2016
5FEF
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BU of 5fef by Molmil
Crystal structure of the allergen profilin (Zea m 12)
Descriptor: GLYCEROL, Profilin-5
Authors:Mares-Mejia, I, Rodriguez-Romero, A.
Deposit date:2015-12-16
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
Sci Rep, 6, 2016
5FDS
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BU of 5fds by Molmil
Crystal structure of the monomeric allergen profilin (Hev b 8)
Descriptor: GLYCEROL, Profilin-2, SULFATE ION
Authors:Mares-Mejia, I, Rodriguez-Romero, A.
Deposit date:2015-12-16
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
Sci Rep, 6, 2016
5EVE
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BU of 5eve by Molmil
Crystal structure of Amb a 8 in complex with poly-Pro10
Descriptor: Poly-Proline peptide, Profilin
Authors:Offermann, L.R, Schlachter, C.R, Garrett, J, Chruszcz, M.
Deposit date:2015-11-19
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
5EV0
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BU of 5ev0 by Molmil
Crystal structure of ragweed profilin Amb a 8 in complex with poly-Pro14
Descriptor: PRO-PRO-PRO-PRO-PRO-PRO-PRO-PRO-PRO, Profilin
Authors:Offermann, L.R, He, J.Z, Perdue, M.L, Chruszcz, M.
Deposit date:2015-11-19
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
5EM1
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BU of 5em1 by Molmil
Crystal structure of ragweed allergen Amb a 8
Descriptor: BENZOIC ACID, CHLORIDE ION, Profilin
Authors:Offermann, L.R, He, J.Z, Perdue, M.L, Chruszcz, M.
Deposit date:2015-11-05
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
5EM0
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BU of 5em0 by Molmil
Crystal structure of mugwort allergen Art v 4
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Pollen allergen Art v 4.01, SODIUM ION
Authors:Offermann, L.R, Perdue, M.L, Chruszcz, M.
Deposit date:2015-11-05
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
4X25
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BU of 4x25 by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Descriptor: Profilin-1
Authors:Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
Deposit date:2014-11-25
Release date:2015-06-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4X1L
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BU of 4x1l by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Descriptor: PHOSPHATE ION, Profilin-1
Authors:Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X1M
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BU of 4x1m by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Descriptor: Profilin-1
Authors:Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4D60
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BU of 4d60 by Molmil
Structure of a dimeric Plasmodium falciparum profilin mutant
Descriptor: PROFILIN, SULFATE ION
Authors:Bhargav, S.P, Vahokoski, J, Kallio, J.P, Torda, A, Kursula, P, Kursula, I.
Deposit date:2014-11-07
Release date:2015-06-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Two Independently Folding Units of Plasmodium Profilin Suggest Evolution Via Gene Fusion.
Cell.Mol.Life Sci., 72, 2015
4QWO
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BU of 4qwo by Molmil
1.52 Angstrom Crystal Structure of A42R Profilin-like Protein from Monkeypox Virus Zaire-96-I-16
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ...
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Flores, K, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-07-16
Release date:2014-08-06
Last modified:2022-10-12
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure of the Monkeypox virus profilin-like protein A42R reveals potential functional differences from cellular profilins.
Acta Crystallogr.,Sect.F, 78, 2022
4ESP
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BU of 4esp by Molmil
Crystal Structure of Peanut Allergen Ara h 5
Descriptor: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Profilin
Authors:Wang, Y, Zhang, Y.Z.
Deposit date:2012-04-23
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal Structure of Peanut ( Arachis hypogaea ) Allergen Ara h 5.
J.Agric.Food Chem., 61, 2013
3UB5
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BU of 3ub5 by Molmil
Profilin:actin with a wide open nucleotide cleft
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Porta, J.C, Borgstahl, G.E.
Deposit date:2011-10-23
Release date:2012-04-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for profilin-mediated actin nucleotide exchange.
J.Mol.Biol., 418, 2012
3U4L
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BU of 3u4l by Molmil
Cryocooled bovine profilin:actin crystal structure to 2.4 A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Porta, J.C, Borgstahl, G.E.
Deposit date:2011-10-09
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for profilin-mediated actin nucleotide exchange.
J.Mol.Biol., 418, 2012
3NEC
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BU of 3nec by Molmil
Crystal Structure of Toxoplasma gondii Profilin
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Inflammatory profilin, SULFATE ION
Authors:Kucera, K, Modis, Y.
Deposit date:2010-06-08
Release date:2010-09-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.
J.Mol.Biol., 403, 2010
2JKF
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BU of 2jkf by Molmil
Plasmodium falciparum profilin
Descriptor: PROFILIN
Authors:Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum
Structure, 16, 2008
2JKG
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BU of 2jkg by Molmil
Plasmodium falciparum profilin
Descriptor: MAGNESIUM ION, OCTAPROLINE PEPTIDE, PROFILIN
Authors:Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum.
Structure, 16, 2008
3DAV
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BU of 3dav by Molmil
Schizosaccharomyces Pombe Profilin crystallized from Sodium formate
Descriptor: Profilin, SODIUM ION
Authors:Ezezika, O.C, Nolen, B.J, Pollard, T.D.
Deposit date:2008-05-30
Release date:2008-12-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN.
J.Biol.Chem., 284, 2009
3D9Y
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BU of 3d9y by Molmil
Crystal Structure of Profilin from Schizosaccharomyces pombe
Descriptor: GLYCEROL, Profilin
Authors:Ezezika, O.C, Nolen, B.J, Pollard, T.D.
Deposit date:2008-05-28
Release date:2008-12-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN.
J.Biol.Chem., 284, 2009
3CHW
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BU of 3chw by Molmil
Complex of Dictyostelium discoideum Actin with Profilin and the Last Poly-Pro of Human VASP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Major actin, ...
Authors:Baek, K, Dominguez, R.
Deposit date:2008-03-10
Release date:2008-08-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2VK3
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BU of 2vk3 by Molmil
Crystal structure of rat profilin 2a
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, PROFILIN-2, ...
Authors:Haikarainen, T, Kursula, P.
Deposit date:2007-12-17
Release date:2009-02-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure, Modifications and Ligand-Binding Properties of Rat Profilin 2A.
Acta Crystallogr.,Sect.D, 65, 2009
2V8F
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BU of 2v8f by Molmil
Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
Authors:Kursula, P, Kursula, I, Downer, J, Witke, W, Wilmanns, M.
Deposit date:2007-08-07
Release date:2007-12-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2V8C
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BU of 2v8c by Molmil
Mouse Profilin IIa in complex with the proline-rich domain of VASP
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
Authors:Kursula, P, Downer, J, Witke, W, Wilmanns, M.
Deposit date:2007-08-06
Release date:2007-12-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2PBD
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BU of 2pbd by Molmil
Ternary complex of profilin-actin with the poly-PRO-GAB domain of VASP*
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Ferron, F, Rebowski, G, Dominguez, R.
Deposit date:2007-03-28
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP
Embo J., 26, 2007

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