5ND4
 
 | | Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | | 登録日 | 2017-03-07 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
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5ND3
 | | Microtubule-bound MKLP2 motor domain in the with no nucleotide | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ... | | 著者 | Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | | 登録日 | 2017-03-07 | | 公開日 | 2017-10-04 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
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6TIW
 | | Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2) | | 分子名称: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | | 著者 | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | | 登録日 | 2019-11-22 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
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5OAM
 | | Molecular basis of human kinesin-8 function and inhibition | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | | 著者 | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | | 登録日 | 2017-06-23 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Structural basis of human kinesin-8 function and inhibition.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6TA4
 | | Human kinesin-5 motor domain in the AMPPNP state bound to microtubules | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... | | 著者 | Pena, A.P, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | | 登録日 | 2019-10-29 | | 公開日 | 2020-03-04 | | 最終更新日 | 2020-04-15 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
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7LVQ
 | | KIF14[391-743] - AMP-PNP closed state class in complex with a microtubule | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF14, ... | | 著者 | Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H. | | 登録日 | 2021-02-26 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Nat Commun, 12, 2021
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6TA3
 | | Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1) | | 分子名称: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | | 著者 | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | | 登録日 | 2019-10-29 | | 公開日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
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7LVR
 | | KIF14[391-743] - ADP-AlFx closed state class in complex with a microtubule | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H. | | 登録日 | 2021-02-26 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Nat Commun, 12, 2021
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5OCU
 | | Molecular basis of human kinesin-8 function and inhibition | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | | 著者 | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | | 登録日 | 2017-07-03 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Structural basis of human kinesin-8 function and inhibition.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OGC
 | | Molecular basis of human kinesin-8 function and inhibition | | 分子名称: | 4-chloranyl-2-nitro-1-(phenylsulfonyl)benzene, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | | 登録日 | 2017-07-12 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural basis of human kinesin-8 function and inhibition.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8IXG
 | | GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXE
 | | GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXF
 | | GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin non-seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXA
 | | GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXD
 | | GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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8IXB
 | | GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | | 著者 | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
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5HNY
 | | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | 登録日 | 2016-01-19 | | 公開日 | 2016-08-10 | | 最終更新日 | 2016-11-02 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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6VPP
 | | Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... | | 著者 | Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. | | 登録日 | 2020-02-04 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
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7NB8
 | | Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule. | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ... | | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | | 登録日 | 2021-01-25 | | 公開日 | 2021-10-13 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
J.Biol.Chem., 297, 2021
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7NBA
 | | Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule. | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ... | | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | | 登録日 | 2021-01-25 | | 公開日 | 2021-10-13 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
J.Biol.Chem., 297, 2021
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5HNZ
 | | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the nucleotide-free state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | 登録日 | 2016-01-19 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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5HNX
 | | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | 登録日 | 2016-01-19 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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5HNW
 | | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the AMPPNP state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | 登録日 | 2016-01-19 | | 公開日 | 2016-08-10 | | 最終更新日 | 2018-07-25 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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6VPO
 | | Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... | | 著者 | Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. | | 登録日 | 2020-02-04 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
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7N61
 | | structure of C2 projections and MIPs | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FAP147, FAP178, ... | | 著者 | Han, L, Zhang, K. | | 登録日 | 2021-06-07 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
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