8U3B
 
 | | Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A | | 分子名称: | DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Liu, B, Kompaniiets, D, Wang, D. | | 登録日 | 2023-09-07 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res., 52, 2024
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8DQ1
 | | Quorum-sensing receptor RhlR bound to PqsE | | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, DNA (5'-D(*AP*CP*CP*TP*GP*CP*CP*AP*GP*AP*CP*TP*GP*CP*AP*CP*AP*G)-3'), ... | | 著者 | Paczkowski, J.E, Fromme, J.C, Feathers, J.R. | | 登録日 | 2022-07-18 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation.
Structure, 30, 2022
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8DQ0
 | | Quorum-sensing receptor RhlR bound to PqsE | | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, RhlR protein | | 著者 | Paczkowski, J.E, Fromme, J.C, Feathers, J.R. | | 登録日 | 2022-07-18 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation.
Structure, 30, 2022
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8B4A
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8A5S
 | | Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized in dark, measured illuminated. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J. | | 登録日 | 2022-06-15 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | EL222 from Erythrobacter litoralis.
To Be Published
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8A5R
 | | Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized and measured in dark. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J. | | 登録日 | 2022-06-15 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | EL222 from Erythrobacter litoralis.
To Be Published
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7X1K
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7VIM
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7VE6
 | | N-terminal domain of VraR | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator protein VraR | | 著者 | Kumar, J.V, Chen, C, Hsu, C.H. | | 登録日 | 2021-09-08 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus.
Protein Sci., 31, 2022
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7VE5
 | | C-terminal domain of VraR | | 分子名称: | DNA-binding response regulator, MAGNESIUM ION, R1-DNA | | 著者 | Kumar, J.V, Chen, C, Hsu, C.H. | | 登録日 | 2021-09-08 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus.
Protein Sci., 31, 2022
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7R3J
 | | Nativ complex of PqsE and RhlR with the synthetic antagonist mBTL | | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION, ... | | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | | 登録日 | 2022-02-07 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Nat Commun, 13, 2022
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7R3I
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7R3H
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7R3G
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7R3E
 | | Fusion construct of PqsE and RhlR in complex with the synthetic antagonist mBTL | | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase,Regulatory protein RhlR, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION | | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | | 登録日 | 2022-02-07 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Nat Commun, 13, 2022
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7PK5
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7DWM
 | | Crystal structure of the phage VqmA-DPO complex | | 分子名称: | 3,5-dimethylpyrazin-2-ol, Transcriptional regulator | | 著者 | Gu, Y, Yang, W.S. | | 登録日 | 2021-01-17 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Understanding the mechanism of asymmetric gene regulation determined by the VqmA of vibriophage.
Biochem.Biophys.Res.Commun., 558, 2021
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6ZJ2
 | | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter rprA in the presence of phosphomimetic BeF3- | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*TP*CP*AP*GP*AP*TP*TP*CP*GP*TP*CP*TP*CP*AP*AP*TP*AP*GP*G)-3'), MAGNESIUM ION, ... | | 著者 | Huesa, J, Marina, A, Casino, P. | | 登録日 | 2020-06-27 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon.
Nucleic Acids Res., 49, 2021
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6ZIX
 | | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter P1flhDC in the presence of phosphomimetic BeF3- | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P1flhDC promoter sequence of 23 bp, ... | | 著者 | Huesa, J, Marina, A, Casino, P. | | 登録日 | 2020-06-26 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon.
Nucleic Acids Res., 49, 2021
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6V7X
 | | Structure of a phage-encoded quorum sensing anti-activator, Aqs1 bound to LasR | | 分子名称: | N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, QUORUM SENSING ANTI-ACTIVATOR PROTEIN AQS1, Transcriptional regulator LasR | | 著者 | Shah, M, Moraes, T.F, Maxwell, K.L. | | 登録日 | 2019-12-09 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.
Mol.Cell, 81, 2021
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6V7W
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6UGL
 | | VqmA bound to DPO | | 分子名称: | 3,5-dimethylpyrazin-2(1H)-one, Helix-turn-helix transcriptional regulator | | 著者 | Paczkowski, J.E, Huang, X. | | 登録日 | 2019-09-26 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Mechanism underlying autoinducer recognition in theVibrio choleraeDPO-VqmA quorum-sensing pathway.
J.Biol.Chem., 295, 2020
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6MWZ
 | | LasR LBD T75V/Y93F/A127W:BB0126 | | 分子名称: | 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ALA-HIS-HIS-HIS-HIS-ALA, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.657 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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6MWW
 | | LasR LBD:BB0126 complex | | 分子名称: | 4-[3-(methylsulfonyl)phenoxy]-N-[(1R,3R,5R)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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6MWL
 | | LasR LBD:mBTL complex | | 分子名称: | 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, Transcriptional regulator LasR | | 著者 | Bassler, B.L, Paczkowski, J.E. | | 登録日 | 2018-10-29 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
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