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3UZS	Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex Descriptor: Beta-adrenergic receptor kinase 1, C13.28 RNA Aptamer, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Tesmer, J.J.G, Tesmer, V.M. Deposit date: 2011-12-07 Release date: 2012-07-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (4.52 Å) Cite: Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20, 2012
3BJI	Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 Descriptor: Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION Authors: Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) Deposit date: 2007-12-04 Release date: 2008-07-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J.Mol.Biol., 380, 2008
2PZ1	Crystal Structure of Auto-inhibited Asef Descriptor: Rho guanine nucleotide exchange factor 4 Authors: Betts, L, Sondek, J, Rossman, K.L. Deposit date: 2007-05-17 Release date: 2007-08-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression. Nat.Struct.Mol.Biol., 14, 2007
1YM7	G Protein-Coupled Receptor Kinase 2 (GRK2) Descriptor: Beta-adrenergic receptor kinase 1 Authors: Lodowski, D.T, Barnhill, J.F, Pyskadlo, R.M, Ghirlando, R, Sterne-Marr, R, Tesmer, J.J.G. Deposit date: 2005-01-20 Release date: 2005-07-05 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (4.5 Å) Cite: The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2 Biochemistry, 44, 2005
2VRW	Critical structural role for the PH and C1 domains of the Vav1 exchange factor Descriptor: PROTO-ONCOGENE VAV, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, ZINC ION Authors: Rapley, J, Tybulewicz, V, Rittinger, K. Deposit date: 2008-04-16 Release date: 2008-06-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor. Embo Rep., 9, 2008
2BCJ	Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits Descriptor: G-protein-coupled receptor kinase 2, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Tesmer, J.J.G. Deposit date: 2005-10-19 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.061 Å) Cite: Snapshot of Activated G Proteins at the Membrane: The Gq-GRK2-G Complex Science, 310, 2005
2DX1	Crystal structure of RhoGEF protein Asef Descriptor: Rho guanine nucleotide exchange factor 4 Authors: Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-08-22 Release date: 2007-01-02 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism J.Biol.Chem., 282, 2007
2DFK	Crystal structure of the CDC42-Collybistin II complex Descriptor: GLYCEROL, SULFATE ION, cell division cycle 42 isoform 1, ... Authors: Xiang, S, Kim, E.Y, Connelly, J.J, Nassar, N, Kirsch, J, Winking, J, Schwarz, G, Schindelin, H. Deposit date: 2006-03-02 Release date: 2006-05-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor. J.Mol.Biol., 359, 2006

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