5VWR
 
 | | E.coli Aspartate aminotransferase-(1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP)-alpha-ketoglutarate | | 分子名称: | (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-glutamic acid, Aspartate aminotransferase, GLYCEROL | | 著者 | Mascarenhas, R, Liu, D, Le, H, Silverman, R. | | 登録日 | 2017-05-22 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
Biochemistry, 56, 2017
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5VWQ
 | | E.coli Aspartate aminotransferase-(1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP) | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase | | 著者 | Mascarenhas, R, Lehrer, H, Liu, D, Ringe, D. | | 登録日 | 2017-05-22 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
Biochemistry, 56, 2017
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5VNX
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5WMK
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5WMH
 | | Arabidopsis thaliana prephenate aminotransferase | | 分子名称: | Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Holland, C.K, Jez, J.M. | | 登録日 | 2017-07-28 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis.
Plant J., 94, 2018
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4BMK
 | | Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine | | 分子名称: | Decarboxylated Myriocin, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Wadsworth, J.M, Clarke, D.J, McMahon, S.A, Beattie, A.E, Lowther, J, Dunn, T.M, Naismith, J.H, Campopiano, D.J. | | 登録日 | 2013-05-09 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin.
J.Am.Chem.Soc., 135, 2013
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1FG7
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4CVQ
 | | CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION | | 分子名称: | ACETATE ION, GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, GLYCEROL, ... | | 著者 | Penya-Soler, E, Fernandez, F.J, Lopez-Estepa, M, Garces, F, Richardson, A.J, Rudd, K.E, Coll, M, Vega, M.C. | | 登録日 | 2014-03-28 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.
PLoS ONE, 9, 2014
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1FC4
 | | 2-AMINO-3-KETOBUTYRATE COA LIGASE | | 分子名称: | 2-AMINO-3-KETOBUTYRATE CONENZYME A LIGASE, 2-AMINO-3-KETOBUTYRIC ACID, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Schmidt, A, Matte, A, Li, Y, Sivaraman, J, Larocque, R, Schrag, J.D, Smith, C, Sauve, V, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2000-07-17 | | 公開日 | 2001-05-02 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.
Biochemistry, 40, 2001
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1FG3
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1GD9
 | | CRYSTALL STRUCTURE OF PYROCOCCUS PROTEIN-A1 | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Ura, H, Harata, K, Matsui, I, Kuramitsu, S. | | 登録日 | 2000-09-22 | | 公開日 | 2001-09-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Temperature dependence of the enzyme-substrate recognition mechanism.
J.Biochem., 129, 2001
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1GC3
 | | THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 COMPLEXED WITH TRYPTOPHAN | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN | | 著者 | Ura, H, Nakai, T, Hirotsu, K, Kuramitsu, S. | | 登録日 | 2000-07-18 | | 公開日 | 2001-09-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Substrate recognition mechanism of thermophilic dual-substrate enzyme.
J.Biochem., 130, 2001
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1G7X
 | | ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R292L/R386L | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Mizuguchi, H, Hayashi, H, Okada, K, Miyahara, I, Hirotsu, K, Kagamiyama, H. | | 登録日 | 2000-11-15 | | 公開日 | 2000-11-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
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1GEY
 | | CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH N-(5'-PHOSPHOPYRIDOXYL)-L-GLUTAMATE | | 分子名称: | 4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM, HISTIDINOL-PHOSPHATE AMINOTRANSFERASE | | 著者 | Haruyama, K, Nakai, T, Miyahara, I, Hirotsu, K, Mizuguchi, H, Hayashi, H, Kagamiyama, H. | | 登録日 | 2000-11-30 | | 公開日 | 2001-04-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry, 40, 2001
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1GEW
 | | CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE | | 分子名称: | HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Haruyama, K, Nakai, T, Miyahara, I, Hirotsu, K, Mizuguchi, H, Hayashi, H, Kagamiyama, H. | | 登録日 | 2000-11-30 | | 公開日 | 2001-04-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry, 40, 2001
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1G4X
 | | ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R292L | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Mizuguchi, H. | | 登録日 | 2000-10-29 | | 公開日 | 2000-11-22 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
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1GC4
 | | THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 COMPLEXED WITH ASPARTATE | | 分子名称: | ASPARTATE AMINOTRANSFERASE, ASPARTIC ACID, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Ura, H, Nakai, T, Hirotsu, K, Kuramitsu, S. | | 登録日 | 2000-07-19 | | 公開日 | 2001-09-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Substrate recognition mechanism of thermophilic dual-substrate enzyme.
J.Biochem., 130, 2001
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1G4V
 | | ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/Y225F | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Mizuguchi, H, Hayashi, H, Okada, K, Miyahara, I, Hirotsu, K, Kagamiyama, H. | | 登録日 | 2000-10-28 | | 公開日 | 2000-11-22 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
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1G7W
 | | ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R386L | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Mizuguchi, H, Hayashi, H, Okada, K, Miyahara, I, Hirotsu, K, Kagamiyama, H. | | 登録日 | 2000-11-15 | | 公開日 | 2000-11-29 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
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1GCK
 | | THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE DOUBLE MUTANT 1 COMPLEXED WITH ASPARTATE | | 分子名称: | ASPARTATE AMINOTRANSFERASE, ASPARTIC ACID, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Ura, H, Nakai, T, Hirotsu, K, Kuramitsu, S. | | 登録日 | 2000-08-04 | | 公開日 | 2001-11-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Substrate recognition mechanism of thermophilic dual-substrate enzyme.
J.Biochem., 130, 2001
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4DBC
 | | Substrate Activation in Aspartate Aminotransferase | | 分子名称: | (E)-N-{2-hydroxy-3-methyl-6-[(phosphonooxy)methyl]benzylidene}-L-aspartic acid, 1,2-ETHANEDIOL, Aspartate aminotransferase, ... | | 著者 | Toney, M.D, Fisher, A.J, Griswold, W.R. | | 登録日 | 2012-01-14 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase.
J.Am.Chem.Soc., 134, 2012
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1GDE
 | | CRYSTAL STRUCTURE OF PYROCOCCUS PROTEIN A-1 E-FORM | | 分子名称: | ASPARTATE AMINOTRANSFERASE, GLUTAMIC ACID, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Ura, H, Harata, K, Matsui, I, Kuramitsu, S. | | 登録日 | 2000-09-23 | | 公開日 | 2001-09-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Temperature dependence of the enzyme-substrate recognition mechanism.
J.Biochem., 129, 2001
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1GEX
 | | CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH HISTIDINOL-PHOSPHATE | | 分子名称: | HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Haruyama, K, Nakai, T, Miyahara, I, Hirotsu, K, Mizuguchi, H, Hayashi, H, Kagamiyama, H. | | 登録日 | 2000-11-30 | | 公開日 | 2001-04-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry, 40, 2001
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4DQ6
 | | Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 | | 分子名称: | CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Putative pyridoxal phosphate-dependent transferase | | 著者 | Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-02-15 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of putative aminotransferase from Clostridium difficile
630
to be published
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4DGT
 | | Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-01-26 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structures of putative aminotransferase from Clostridium difficile
630
to be published
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