PDB: 143 resultsInfo pagesStatus searchChemie searchBIRD

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6PK4	cryoEM structure of the substrate-bound human CTP synthase 2 filament Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase 2, URIDINE 5'-TRIPHOSPHATE Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2019-06-28 Release date: 2019-12-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments. Nat.Struct.Mol.Biol., 27, 2020
7RMC	Yeast CTP Synthase (Ura7) filament bound to CTP at low pH Descriptor: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-27 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
4ZDI	Crystal structure of the M. tuberculosis CTP synthase PyrG (apo form) Descriptor: CALCIUM ION, CTP synthase Authors: Bellinzoni, M, Barilone, N, Alzari, P.M. Deposit date: 2015-04-17 Release date: 2015-07-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.52 Å) Cite: Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. Chem.Biol., 22, 2015
4WIM	Crystal Structure of the GMP Synthetase from Plasmodium falciparum Descriptor: GMP synthetase Authors: Ballut, L, Violot, S, Haser, R, Aghajari, N. Deposit date: 2014-09-26 Release date: 2015-12-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6, 2015
7RNL	Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-29 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RL5	Yeast CTP Synthase (URA8) filament bound to CTP at low pH Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-23 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
5U3C	CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution Descriptor: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE Authors: Kollman, J.M, Lynch, E.M. Deposit date: 2016-12-01 Release date: 2017-04-26 Last modified: 2017-06-21 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
5U6R	E. coli CTP synthase CC mutant filament (product-bound) Descriptor: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE Authors: Kollman, J.M, Lynch, E.M. Deposit date: 2016-12-08 Release date: 2017-04-26 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
6L6Z	Cryo-EM structure of the Drosophila CTP synthase substrate-bound filament Descriptor: CTP synthase Authors: Ji-Long, L, Xian, Z, Chen-Jun, G. Deposit date: 2019-10-30 Release date: 2020-03-18 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (6.09 Å) Cite: Drosophila CTP synthase can form distinct substrate- and product-bound filaments. J Genet Genomics, 46, 2019
5U03	Cryo-EM structure of the human CTP synthase filament Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase 1, URIDINE 5'-TRIPHOSPHATE Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2016-11-22 Release date: 2017-04-26 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
7MH0	Human CTPS1 bound to CTP Descriptor: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2021-04-14 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7RMK	Yeast CTP Synthase (Ura7) Bundle bound to substrates at low pH Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-27 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMV	Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-28 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (6.7 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMO	Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-27 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (7 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMF	Substrate-bound Ura7 filament at low pH Descriptor: CTP synthase Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-27 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (7.3 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
5U05	Cryo-EM structure of the E. coli CTP synthase tetramer Descriptor: CTP synthase Authors: Lynch, E.M, Hicks, D.R, Kollman, J.M. Deposit date: 2016-11-22 Release date: 2017-04-26 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (7.9 Å) Cite: Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
6LFG	Cryo-EM structure of the Drosophila CTP synthase product-bound filament Descriptor: CTP synthase Authors: Ji-long, L, Xian, Z, Chen-Jun, G. Deposit date: 2019-12-02 Release date: 2020-03-18 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (9.58 Å) Cite: Drosophila CTP synthase can form distinct substrate- and product-bound filaments. J Genet Genomics, 46, 2019
2LXN	Solution NMR structure of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii Descriptor: GMP synthase [glutamine-hydrolyzing] subunit A Authors: Ali, R, Kumar, S, Balaram, H, Sarma, S.P. Deposit date: 2012-08-30 Release date: 2013-06-12 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: 1H, 13C, 15N assignment and secondary structure determination of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii Biomol.Nmr Assign., 6, 2012

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