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8UQE
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BU of 8uqe by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.562 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQD
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BU of 8uqd by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (condition 2. RING not modeled in density)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.893 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQC
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BU of 8uqc by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 2)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQB
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BU of 8uqb by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1)
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQA
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BU of 8uqa by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ...
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQ9
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BU of 8uq9 by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 4-residue linker
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ...
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQ8
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BU of 8uq8 by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 2-residue linker
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ...
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UPF
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BU of 8upf by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168-UbcH5c
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-10-22
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8U14
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BU of 8u14 by Molmil
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 2)
分子名称: DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-08-30
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8U13
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BU of 8u13 by Molmil
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 1)
分子名称: DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-08-30
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8TXX
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BU of 8txx by Molmil
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 3)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-08-24
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8TXW
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BU of 8txw by Molmil
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-08-24
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8TXV
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BU of 8txv by Molmil
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 1)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-08-24
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8T3Y
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BU of 8t3y by Molmil
Structure of Bre1-nucleosome complex - state1
分子名称: 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-08
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
8T3W
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BU of 8t3w by Molmil
Structure of Bre1-nucleosome complex - state2
分子名称: 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
8T3T
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BU of 8t3t by Molmil
Structure of Bre1-nucleosome complex - state3
分子名称: 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
8SNA
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BU of 8sna by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN9
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BU of 8sn9 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN8
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BU of 8sn8 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 6)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN7
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BU of 8sn7 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 5)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN6
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BU of 8sn6 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 4)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN5
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BU of 8sn5 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN4
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BU of 8sn4 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 2)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN3
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BU of 8sn3 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 1)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN2
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BU of 8sn2 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024

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件を2024-05-01に公開中

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