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2A55
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BU of 2a55 by Molmil
Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.
Descriptor: C4b-binding protein
Authors:Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N.
Deposit date:2005-06-30
Release date:2005-12-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J.Biol.Chem., 281, 2006
8ACF
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BU of 8acf by Molmil
Structure of the argX-117 in complex with a complement C2 fragment at low pH
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2022-07-05
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
8ACI
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BU of 8aci by Molmil
Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ARGX-117 Fab heavy chain, ARGX-117 Fab light chain, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2022-07-05
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
1GKG
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BU of 1gkg by Molmil
Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)
Descriptor: COMPLEMENT RECEPTOR TYPE 1
Authors:Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N.
Deposit date:2001-08-14
Release date:2002-04-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
Cell(Cambridge,Mass.), 108, 2002
1GKN
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BU of 1gkn by Molmil
Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)
Descriptor: COMPLEMENT RECEPTOR TYPE 1
Authors:Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N.
Deposit date:2001-08-16
Release date:2002-04-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
Cell(Cambridge,Mass.), 108, 2002
1H04
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BU of 1h04 by Molmil
Human CD55 domains 3 & 4
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR, NICKEL (II) ION
Authors:Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M.
Deposit date:2002-06-11
Release date:2003-03-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
1H2P
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BU of 1h2p by Molmil
Human CD55 domains 3 & 4
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR
Authors:Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M.
Deposit date:2002-08-13
Release date:2003-03-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
1H03
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BU of 1h03 by Molmil
Human CD55 domains 3 & 4
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR
Authors:Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M.
Deposit date:2002-06-11
Release date:2003-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
1HCC
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BU of 1hcc by Molmil
THREE-DIMENSIONAL STRUCTURE OF A COMPLEMENT CONTROL PROTEIN MODULE IN SOLUTION
Descriptor: 16TH COMPLEMENT CONTROL PROTEIN
Authors:Norman, D.G, Barlow, P.B, Campbell, I.D.C.
Deposit date:1990-11-28
Release date:1992-04-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional structure of a complement control protein module in solution.
J.Mol.Biol., 219, 1991
1HAQ
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BU of 1haq by Molmil
FOUR MODELS OF HUMAN FACTOR H DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING
Descriptor: COMPLEMENT FACTOR H
Authors:Aslam, M, Perkins, S.J.
Deposit date:2001-04-06
Release date:2002-04-05
Last modified:2024-05-08
Method:SOLUTION SCATTERING
Cite:Folded-Back Solution Structure of Monomeric Factor H of Human Complement by Synchrotron X-Ray and Neutron Scattering, Analytical Ultracentrifugation and Constrained Molecular Modelling.
J.Mol.Biol., 309, 2001
1H2Q
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BU of 1h2q by Molmil
Human CD55 domains 3 & 4
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR
Authors:Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Powell, R, Spiller, O.B, Evans, D.J, Lea, S.M.
Deposit date:2002-08-13
Release date:2003-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
1HFH
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BU of 1hfh by Molmil
SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
Descriptor: FACTOR H, 15TH AND 16TH C-MODULE PAIR
Authors:Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
Deposit date:1993-02-23
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
1HFI
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BU of 1hfi by Molmil
SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
Descriptor: FACTOR H, 15TH C-MODULE PAIR
Authors:Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
Deposit date:1993-02-23
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
8CI3
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BU of 8ci3 by Molmil
Structure of bovine CD46 ectodomain (SCR 1-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Aitkenhead, H, David I Stuart, D.I, El Omari, K.
Deposit date:2023-02-08
Release date:2023-07-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure of Bovine CD46 Ectodomain.
Viruses, 15, 2023
8CJV
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BU of 8cjv by Molmil
Structure of bovine CD46 ectodomain (SCR 1-4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane cofactor protein
Authors:Aitkenhead, H, Stuart, D.I, El Omari, K.
Deposit date:2023-02-13
Release date:2023-07-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of Bovine CD46 Ectodomain.
Viruses, 15, 2023
3ZD2
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BU of 3zd2 by Molmil
THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE
Descriptor: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1
Authors:Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
Deposit date:2012-11-23
Release date:2013-03-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZD1
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BU of 3zd1 by Molmil
STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2
Descriptor: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2
Authors:Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
Deposit date:2012-11-23
Release date:2013-03-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
4B2S
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BU of 4b2s by Molmil
Solution structure of CCP modules 11-12 of complement factor H
Descriptor: COMPLEMENT FACTOR H
Authors:Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N.
Deposit date:2012-07-17
Release date:2012-10-17
Last modified:2013-05-08
Method:SOLUTION NMR
Cite:Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012
4B2R
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BU of 4b2r by Molmil
Solution structure of CCP modules 10-11 of complement factor H
Descriptor: COMPLEMENT FACTOR H
Authors:Makou, E, Mertens, H.D.T, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N.
Deposit date:2012-07-17
Release date:2012-10-10
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012
1OK1
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BU of 1ok1 by Molmil
Decay accelerating factor (cd55) : the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK9
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BU of 1ok9 by Molmil
Decay accelerating factor (CD55): The structure of an intact human complement regulator.
Descriptor: ACETATE ION, CHLORIDE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-21
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJW
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BU of 1ojw by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, SULFATE ION
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK3
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BU of 1ok3 by Molmil
Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJV
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BU of 1ojv by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJY
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BU of 1ojy by Molmil
Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004

219869

數據於2024-05-15公開中

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