5KBK
| Candida Albicans Superoxide Dismutase 5 (SOD5), E110A Mutant | 分子名称: | COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION | 著者 | Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J. | 登録日 | 2016-06-03 | 公開日 | 2016-08-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.411 Å) | 主引用文献 | The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases. J.Biol.Chem., 291, 2016
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4XCR
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M. | 登録日 | 2014-12-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.602 Å) | 主引用文献 | Thermodynamics of protein destabilization in live cells. Proc. Natl. Acad. Sci. U.S.A., 112, 2015
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4FF9
| Crystal Structure of cysteinylated WT SOD1. | 分子名称: | COPPER (II) ION, CYSTEINE, Superoxide dismutase [Cu-Zn], ... | 著者 | Auclair, J.R, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Petsko, G.A, Agar, J.N. | 登録日 | 2012-05-31 | 公開日 | 2013-09-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5003 Å) | 主引用文献 | Structural consequences of cysteinylation of cu/zn-superoxide dismutase. Biochemistry, 52, 2013
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5CU9
| CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO | 分子名称: | Cell surface Cu-only superoxide dismutase 5, SULFATE ION | 著者 | Waninger-Saroni, J.J, Taylor, A.B, Hart, P.J, Galaleldeen, A. | 登録日 | 2015-07-24 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO To Be Published
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7NXX
| Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | 著者 | Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. | 登録日 | 2021-03-19 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | 主引用文献 | Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1 To Be Published
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8CCX
| Human SOD1 in complex with S-XL6 cross-linker | 分子名称: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | 登録日 | 2023-01-27 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS. Plos Biol., 22, 2024
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8GSQ
| Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. | 分子名称: | (9~{R})-3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-9-oxidanyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one, GLYCEROL, Superoxide dismutase [Cu-Zn], ... | 著者 | Aouti, S, Padmanabhan, B. | 登録日 | 2022-09-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based discovery of an antipsychotic drug, paliperidone, as a modulator of human superoxide dismutase 1: a potential therapeutic target in amyotrophic lateral sclerosis. Acta Crystallogr D Struct Biol, 79, 2023
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5O40
| SOD1 bound to Ebselen | 分子名称: | N-phenyl-2-selanylbenzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | 登録日 | 2017-05-25 | 公開日 | 2018-06-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9, 2018
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5O3Y
| SOD1 bound to Ebsulfur | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | 登録日 | 2017-05-25 | 公開日 | 2018-06-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9, 2018
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7FB6
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6VBS
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7FB9
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6VBT
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4RVP
| Crystal structure of superoxide dismutase from sedum alfredii | 分子名称: | ZINC ION, superoxide dismutase | 著者 | Qiu, R, Li, C, Zhai, J, Tang, L, Zhang, H, Yuan, M, Hu, X. | 登録日 | 2014-11-27 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The positive effects of Cd and Cd-Zn relationship in the
Zn-related physiological processes involved in growth in the Zn/Cd hyperaccumulator Sedum alfredii To be Published
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4U4I
| Megavirus chilensis superoxide dismutase | 分子名称: | Cu/Zn superoxide dismutase | 著者 | Lartigue, A, Claverie, J.-M, Burlat, B, Coutard, B, Abergel, C. | 登録日 | 2014-07-23 | 公開日 | 2014-11-05 | 最終更新日 | 2014-12-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The megavirus chilensis cu,zn-superoxide dismutase: the first viral structure of a typical cellular copper chaperone-independent hyperstable dimeric enzyme. J.Virol., 89, 2015
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3S0P
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3SOD
| CHANGES IN CRYSTALLOGRAPHIC STRUCTURE AND THERMOSTABILITY OF A CU,ZN SUPEROXIDE DISMUTASE MUTANT RESULTING FROM THE REMOVAL OF BURIED CYSTEINE | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Mcree, D.E, Redford, S.M, Getzoff, E.D, Lepock, J.R, Hallewell, R.A, Tainer, J.A. | 登録日 | 1990-06-26 | 公開日 | 1993-04-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine. J.Biol.Chem., 265, 1990
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1AZV
| FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN) | 分子名称: | COPPER (II) ION, COPPER/ZINC SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Hart, P.J, Liu, H, Pellegrini, M, Nersissian, A.M, Gralla, E.B, Valentine, J.S, Eisenberg, D. | 登録日 | 1997-11-21 | 公開日 | 1998-02-25 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis. Protein Sci., 7, 1998
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1B4T
| H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE | 分子名称: | CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ... | 著者 | Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. | 登録日 | 1998-12-23 | 公開日 | 1999-12-23 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
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1B4L
| 15 ATMOSPHERE OXYGEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE | 分子名称: | COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ZINC ION | 著者 | Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. | 登録日 | 1998-12-22 | 公開日 | 1999-12-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
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3T5W
| 2ME modified human SOD1 | 分子名称: | COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Ihara, K, Yamaguchi, Y, Torigoe, H, Wakatsuki, S, Taniguchi, N, Suzuki, K, Fujiwara, N. | 登録日 | 2011-07-28 | 公開日 | 2012-08-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme Biosci.Rep., 32, 2012
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1BA9
| THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES | 分子名称: | COPPER (I) ION, SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Banci, L, Benedetto, M, Bertini, I, Del Conte, R, Piccioli, M, Viezzoli, M.S. | 登録日 | 1998-04-24 | 公開日 | 1998-09-16 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?. Biochemistry, 37, 1998
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7B4O
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7B4P
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8JD8
| Crystal structure of Citrus limon Cu-Zn superoxide dismutase | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T. | 登録日 | 2023-05-12 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon. Acta Crystallogr.,Sect.F, 79, 2023
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