PDB: 255 resultsInfo pagesStatus searchChemie searchBIRD

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3F5N	Structure of native human neuroserpin Descriptor: Neuroserpin Authors: Ricagno, S, Caccia, S, Sorrentino, G, Bolognesi, M. Deposit date: 2008-11-04 Release date: 2009-05-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Human neuroserpin: structure and time-dependent inhibition J.Mol.Biol., 388, 2009
5OM3	Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER Authors: Schmidt, K, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3FGQ	Crystal structure of native human neuroserpin Descriptor: GLYCEROL, Neuroserpin Authors: Takehara, S, Yang, X, Mikami, B, Onda, M. Deposit date: 2008-12-08 Release date: 2009-04-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.09 Å) Cite: The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability J.Mol.Biol., 388, 2009
3ZHA	Molecular basis for the action of the collagen-specific chaperone Hsp47 SERPINH1 and its structure-specific client recognition. Descriptor: COLLAGEN MODEL PEPTIDE 18-T8R11, HSP47, SUCCINIC ACID Authors: Widmer, C, Gebauer, J.M, Baumann, U. Deposit date: 2012-12-20 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4AQH	Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976 Descriptor: PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE Authors: Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D. Deposit date: 2012-04-17 Release date: 2012-11-28 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation J.Biol.Chem., 288, 2013
4AJT	The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI) Descriptor: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR Authors: Yan, Y, Zhou, A. Deposit date: 2012-02-19 Release date: 2012-12-05 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AJU	Crystal structure of the reactive loop cleaved ZPI in P41 space group Descriptor: 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION Authors: Zhou, A, Yan, Y, Wei, Z. Deposit date: 2012-02-19 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AFX	Crystal structure of the reactive loop cleaved ZPI in I2 space group Descriptor: CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ... Authors: Zhou, A, Yan, Y, Wei, Z. Deposit date: 2012-01-23 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AU4	Crystal Structure of Hsp47 Descriptor: SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, ... Authors: Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U. Deposit date: 2012-05-14 Release date: 2012-08-15 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4AU2	Crystal Structure of a Hsp47-collagen complex Descriptor: 15ER COLLAGEN MODEL PEPTIDE 15-R8, SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), ... Authors: Widmer, C, Gebauer, J.M, Brunstein, E, Drogemuller, C, Leeb, T, Baumann, U. Deposit date: 2012-05-13 Release date: 2012-08-15 Last modified: 2015-04-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4BB2	Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone Descriptor: 1,2-ETHANEDIOL, CORTICOSTEROID-BINDING GLOBULIN, CYSTEINE, ... Authors: Gardill, B.R, Vogl, M.R, Lin, H, Hammond, G.L, Muller, Y.A. Deposit date: 2012-09-19 Release date: 2012-12-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences Plos One, 7, 2012
4C49	Reactive loop cleaved human CBG in complex with cortisol Descriptor: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN Authors: Chan, W.L, Zhou, A, Read, R.J. Deposit date: 2013-09-02 Release date: 2014-10-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg To be Published
4C41	Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236 Descriptor: CORTICOSTEROID-BINDING GLOBULIN Authors: Chan, W.L, Zhou, A, Read, R.J. Deposit date: 2013-08-28 Release date: 2014-10-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents. Plos One, 9, 2014
4CAA	CLEAVED ANTICHYMOTRYPSIN T345R Descriptor: ANTICHYMOTRYPSIN Authors: Lukacs, C.M, Christianson, D.W. Deposit date: 1997-08-14 Release date: 1998-02-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
1WZ9	The 2.1 A structure of a tumour suppressing serpin Descriptor: Maspin precursor, SULFATE ION Authors: Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. Deposit date: 2005-03-03 Release date: 2005-03-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
1LQ8	Crystal structure of cleaved protein C inhibitor Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Huntington, J.A, Kjellberg, M, Stenflo, J. Deposit date: 2002-05-09 Release date: 2003-02-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation Structure, 11, 2003
1LK6	Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. Deposit date: 2002-04-24 Release date: 2003-06-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Serpin Polymerization Is Prevented by a Hydrogen Bond Network That Is Centered on His-334 and Stabilized by Glycerol J.Biol.Chem., 278, 2003
1LJ5	1.8A Resolution Structure of Latent Plasminogen Activator Inhibitor-1(PAI-1) Descriptor: ACETIC ACID, DIMETHYL SULFOXIDE, PLASMINOGEN ACTIVATOR INHIBITOR-1 Authors: Stein, P.E, Baek, K. Deposit date: 2002-04-19 Release date: 2002-05-08 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite:
1XU8	The 2.8 A structure of a tumour suppressing serpin Descriptor: Maspin, SULFATE ION Authors: Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. Deposit date: 2004-10-25 Release date: 2005-03-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
1XQG	3.10 A crystal structure of maspin, Space group P 4 21 2 Descriptor: Maspin Authors: Al-Ayyoubi, M, Gettins, P.G, Volz, K. Deposit date: 2004-10-12 Release date: 2004-10-26 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained J.Biol.Chem., 279, 2004
1XQJ	3.10 A Crystal structure of maspin, space group I 4 2 2 Descriptor: Maspin Authors: Al-Ayyoubi, M, Gettins, P.G, Volz, K. Deposit date: 2004-10-12 Release date: 2004-10-26 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained J.Biol.Chem., 279, 2004
1M93	1.65 A Structure of Cleaved Viral Serpin CRMA Descriptor: PHOSPHATE ION, Serine proteinase inhibitor 2 Authors: Simonovic, M, Gettins, P.G.W, Volz, K. Deposit date: 2002-07-26 Release date: 2003-08-05 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition Protein Sci., 9, 2000
1MTP	The X-ray crystal structure of a serpin from a thermophilic prokaryote Descriptor: Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B Authors: Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C. Deposit date: 2002-09-21 Release date: 2003-04-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment Structure, 11, 2003
1NQ9	Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... Authors: Huntington, J.A, Johnson, D.J.D. Deposit date: 2003-01-21 Release date: 2003-09-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State Biochemistry, 42, 2003
1YXA	Serpina3n, a murine orthologue of human antichymotrypsin Descriptor: serine (or cysteine) proteinase inhibitor, clade A, member 3N Authors: Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. Deposit date: 2005-02-20 Release date: 2005-09-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005

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