PDB: 255 resultsInfo pagesStatus searchChemie searchBIRD

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7AHP	Crystal structure of Ixodes ricinus serpin - Iripin-3 Descriptor: Putative salivary serpin, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM Authors: Kascakova, B, Kuta Smatanova, I, Prudnikova, T. Deposit date: 2020-09-25 Release date: 2021-03-10 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Iripin-3, a New Salivary Protein Isolated From Ixodes ricinus Ticks, Displays Immunomodulatory and Anti-Hemostatic Properties In Vitro Front Immunol, 12, 2021
7B2T	Crystal structure of Iripin-5 serpin from Ixodes ricinus Descriptor: CHLORIDE ION, MAGNESIUM ION, Serpin-4 precursor, ... Authors: Kascakova, B, Kuta Smatanova, I. Deposit date: 2020-11-27 Release date: 2021-10-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus. Acta Crystallogr D Struct Biol, 77, 2021
4G8R	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 Descriptor: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION Authors: Stuckey, J.A, Lawrence, D.A, Li, S.-H. Deposit date: 2012-07-23 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
4R9I	Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori Descriptor: BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ... Authors: Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y. Deposit date: 2014-09-05 Release date: 2015-09-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18 Sci Rep, 5, 2015
4G8O	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 Descriptor: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ... Authors: Stuckey, J.A, Lawrence, D.A, Li, S.-H. Deposit date: 2012-07-23 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
4GA7	Crystal structure of human serpinB1 mutant Descriptor: Leukocyte elastase inhibitor Authors: Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. Deposit date: 2012-07-25 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4RSQ	2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae Descriptor: Serpin 2 Authors: Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. Deposit date: 2014-11-10 Release date: 2014-12-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
4ROA	1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae Descriptor: Serpin 2 Authors: Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. Deposit date: 2014-10-28 Release date: 2014-12-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
4RO9	2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae Descriptor: GLYCEROL, Serpin 2 Authors: Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. Deposit date: 2014-10-28 Release date: 2014-12-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
4ROB	2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae Descriptor: Serpin 2 Authors: Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. Deposit date: 2014-10-28 Release date: 2014-12-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae To be Published
4IC0	Crystal Structure of PAI-1 in Complex with Gallate Descriptor: 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1 Authors: Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D. Deposit date: 2012-12-09 Release date: 2013-12-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Crystal Structure of PAI-1 in Complex with Gallate To be Published
2CEO	thyroxine-binding globulin complex with thyroxine Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, GLYCEROL, THYROXINE-BINDING GLOBULIN Authors: Zhou, A, Wei, Z, Read, R.J, Carrell, R.W. Deposit date: 2006-02-08 Release date: 2006-08-14 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Mechanism for the Carriage and Release of Thyroxine in the Blood. Proc.Natl.Acad.Sci.USA, 103, 2006
2DUT	Crystal structure of a M-loop deletion variant of MENT in the native conformation Descriptor: Heterochromatin-associated protein MENT Authors: Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A. Deposit date: 2006-07-26 Release date: 2006-08-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation Embo J., 25, 2006
3LE2	Structure of Arabidopsis AtSerpin1. Native Stressed Conformation Descriptor: ACETATE ION, GLYCEROL, SULFATE ION, ... Authors: Harrop, S.J, Joss, T.V, Cumi, P.M.G, Roberts, T.H. Deposit date: 2010-01-14 Release date: 2010-02-23 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21). J.Biol.Chem., 285, 2010
3LW2	Mouse Plasminogen Activator Inhibitor-1 (PAI-1) Descriptor: Plasminogen activator inhibitor 1 Authors: Dewilde, M, Van De Craen, B, Compernolle, G, Madsen, J.B, Strelkov, S.V, Gils, A, Declerck, P.J. Deposit date: 2010-02-23 Release date: 2010-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences. J.Struct.Biol., 171, 2010
3NDA	Crystal structure of serpin from tick Ixodes ricinus Descriptor: PENTAETHYLENE GLYCOL, Serpin-2 Authors: Rezacova, P, Kovarova, Z, Chmelar, J, Mares, M. Deposit date: 2010-06-07 Release date: 2010-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood, 117, 2011
3NE4	1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin Descriptor: Alpha-1-antitrypsin Authors: Patschull, A.O.M, Gooptu, B, Segu, L. Deposit date: 2010-06-08 Release date: 2011-12-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution Acta Crystallogr.,Sect.F, 67, 2011
3NDF	Cleaved antitrypsin with P8-P6 Asp Descriptor: Alpha-1-antitrypsin Authors: Huntington, J.A, Sendall, T.J, Yamasaki, M. Deposit date: 2010-06-07 Release date: 2010-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Loop-sheet mechanism of serpin polymerization tested by reactive center loop mutations J. Biol. Chem., 285, 2010
3NDD	Cleaved antitrypsin with P10 Pro, and P9-P6 Asp Descriptor: Alpha-1-antitrypsin Authors: Yamasaki, M, Sendall, T.J, Huntington, J.A. Deposit date: 2010-06-07 Release date: 2010-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Loop-sheet mechanism of serpin polymerization tested by reactive center loop mutations J. Biol. Chem., 285, 2010
2H4R	Crystal structure of wildtype MENT in the native conformation Descriptor: Heterochromatin-associated protein MENT Authors: Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S. Deposit date: 2006-05-25 Release date: 2006-07-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2H4Q	Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation Descriptor: Heterochromatin-associated protein MENT Authors: Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A. Deposit date: 2006-05-25 Release date: 2006-07-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2H4P	Crystal structure of wildtype MENT in the cleaved conformation Descriptor: Heterochromatin-associated protein MENT Authors: Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C. Deposit date: 2006-05-24 Release date: 2006-07-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2HI9	Crystal Structure of human native protein C inhibitor Descriptor: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor Authors: Li, W, Adams, T.E, Huntington, J.A. Deposit date: 2006-06-29 Release date: 2007-03-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of native protein C inhibitor provides insight into its multiple functions. J.Biol.Chem., 282, 2007
2HIJ	Crystal Structure of P14 Alanine Variant of Antithrombin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... Authors: Luis, S.A, Bock, S.C, Huntington, J.A. Deposit date: 2006-06-29 Release date: 2007-06-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal Structure of P14 Alanine Variant of Antithrombin To be Published
3OZQ	Crystal structure of Serpin48, which is a highly specific serpin in the insect Tenebrio molitor Descriptor: Serpin48 Authors: Park, S.H, Piao, S, Ha, N.-C. Deposit date: 2010-09-27 Release date: 2010-10-27 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and functional characterization of a highly specific serpin in the insect innate immunity J.Biol.Chem., 286, 2011

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