3NE4
1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin
Summary for 3NE4
| Entry DOI | 10.2210/pdb3ne4/pdb |
| Descriptor | Alpha-1-antitrypsin (2 entities in total) |
| Functional Keywords | alpha1-antitrypsin, serpin, lung disease, liver disease, polymerisation, hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix: P01009 |
| Total number of polymer chains | 1 |
| Total formula weight | 47619.22 |
| Authors | Patschull, A.O.M.,Gooptu, B.,Segu, L. (deposition date: 2010-06-08, release date: 2011-12-14, Last modification date: 2023-09-06) |
| Primary citation | Patschull, A.O.,Segu, L.,Nyon, M.P.,Lomas, D.A.,Nobeli, I.,Barrett, T.E.,Gooptu, B. Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution Acta Crystallogr.,Sect.F, 67:1492-1497, 2011 Cited by PubMed: 22139150DOI: 10.1107/S1744309111040267 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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