3NE4

1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-1-antitrypsin	polymer	424	47619.2	1	UniProt (P01009) Pfam (PF00079) In PDB	Homo sapiens (human)	Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT
2		water	water		18.0	217	Chemie (HOH)

Sequence modifications

A: 24 - 394 (UniProt: P01009)

PDB	External Database	Details
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Met -23	-	expression tag
Pro -22	-	expression tag
Ser -21	-	expression tag
Ser -20	-	expression tag
Val -19	-	expression tag
Ser -18	-	expression tag
Trp -17	-	expression tag
Gly -16	-	expression tag
Ile -15	-	expression tag
Leu -14	-	expression tag
Leu -13	-	expression tag
Leu -12	-	expression tag
Ala -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Cys -8	-	expression tag
Cys -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Val -3	-	expression tag
Ser -2	-	expression tag
Leu -1	-	expression tag
Ala 0	-	expression tag
Glu 1	-	expression tag
Asp 2	-	expression tag
Pro 3	-	expression tag
Gln 4	-	expression tag
Gly 5	-	expression tag
Asp 6	-	expression tag
Ala 7	-	expression tag
Ala 8	-	expression tag
Gln 9	-	expression tag
Lys 10	-	expression tag
Thr 11	-	expression tag
Asp 12	-	expression tag
Thr 13	-	expression tag
Ser 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Asp 17	-	expression tag
Gln 18	-	expression tag
Asp 19	-	expression tag
His 20	-	expression tag
Pro 21	-	expression tag
Thr 22	-	expression tag
Phe 23	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47619.2
All*	Total formula weight	47619.2

*Water molecules are not included.