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3SXL
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BU of 3sxl by Molmil
SEX-LETHAL RNA RECOGNITION DOMAINS 1 AND 2 FROM DROSOPHILA MELANOGASTER
Descriptor: PROTEIN (SEX-LETHAL)
Authors:Crowder, S.M, Kanaar, R, Rio, D.C, Alber, T.C.
Deposit date:1999-04-04
Release date:1999-04-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Absence of interdomain contacts in the crystal structure of the RNA recognition motifs of Sex-lethal.
Proc.Natl.Acad.Sci.USA, 96, 1999
6GBM
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BU of 6gbm by Molmil
Solution structure of FUS-RRM bound to stem-loop RNA
Descriptor: RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS
Authors:Loughlin, F.E, Allain, F.H.-T.
Deposit date:2018-04-15
Release date:2019-02-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell, 73, 2019
6GD3
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BU of 6gd3 by Molmil
Structure of HuR RRM3 in complex with RNA (UAUUUA)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3'), SODIUM ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
8ONS
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BU of 8ons by Molmil
TAF15 amyloid fold in atypical FTLD - Individual 1
Descriptor: TATA-binding protein-associated factor 2N
Authors:Tetter, S, Ryskeldi-Falcon, B.
Deposit date:2023-04-03
Release date:2023-12-06
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (1.97 Å)
Cite:TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature, 625, 2024
6G2K
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BU of 6g2k by Molmil
Structure of HuR RRM3 in complex with RNA (UUUUUU)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), SULFATE ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-03-23
Release date:2018-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GC5
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Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM
Descriptor: AU-rich RNA, ELAV-like protein 1
Authors:Ripin, N, Allain, F.H.
Deposit date:2018-04-17
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
2X1A
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BU of 2x1a by Molmil
Structure of Rna15 RRM with RNA bound (G)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2X1F
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BU of 2x1f by Molmil
Structure of Rna15 RRM with bound RNA (GU)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2XNR
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BU of 2xnr by Molmil
Structural insights into cis element recognition of non- polyadenylated RNAs by the Nab3-RRM
Descriptor: 5'-R(*UP*UP*CP*UP*UP*AP*UP*UP*CP*UP*UP*A)-3', ACETATE ION, NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3
Authors:Lunde, B.M, Horner, M, Meinhart, A.
Deposit date:2010-08-05
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights Into Cis Element Recognition of Non-Polyadenylated Rnas by the Nab3-Rrm.
Nucleic Acids Res., 39, 2011
2XS2
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BU of 2xs2 by Molmil
Crystal structure of the RRM domain of mouse Deleted in azoospermia-like in complex with RNA, UUGUUCUU
Descriptor: 5'-R(*UP*UP*GP*UP*UP*CP*UP*U)-3', DELETED IN AZOOSPERMIA-LIKE, ZINC ION
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-24
Release date:2011-10-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Kinked beta-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
2XS7
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BU of 2xs7 by Molmil
Crystal structure of the RRM domain of mouse Deleted in azoospermia- like in complex with Sycp3 RNA, UUGUUU
Descriptor: 5'-R(*UP*UP*GP*UP*UP*UP)-3', DELETED IN AZOOSPERMIA-LIKE, ZINC ION
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-24
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Proc.Natl.Acad.Sci.USA, 108, 2011
6GX6
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BU of 6gx6 by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (ACAC)
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ...
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-06-26
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
2XNQ
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BU of 2xnq by Molmil
Structural insights into cis element recognition of non- polyadenylated RNAs by the Nab3-RRM
Descriptor: ACETATE ION, NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3
Authors:Lunde, B.M, Horner, M, Meinhart, A.
Deposit date:2010-08-05
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Insights Into Cis Element Recognition of Non-Polyadenylated Rnas by the Nab3-Rrm.
Nucleic Acids Res., 39, 2011
2XS5
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BU of 2xs5 by Molmil
Crystal structure of the RRM domain of mouse Deleted in azoospermia- like in complex with Mvh RNA, UGUUC
Descriptor: 5'-R(*UP*GP*UP*UP*CP)-3', DELETED IN AZOOSPERMIA-LIKE, DI(HYDROXYETHYL)ETHER
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-24
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Proc.Natl.Acad.Sci.USA, 108, 2011
2XSF
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BU of 2xsf by Molmil
Crystal structure of the RRM domain of mouse Deleted in azoospermia- like
Descriptor: DELETED IN AZOOSPERMIA-LIKE, GLYCEROL, SULFATE ION
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-28
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Proc.Natl.Acad.Sci.USA, 108, 2011
2YH1
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BU of 2yh1 by Molmil
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
6HIP
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BU of 6hip by Molmil
Structure of SPF45 UHM bound to HIV-1 Rev ULM
Descriptor: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ...
Authors:Pabis, M, Corsini, L, Sattler, M.
Deposit date:2018-08-30
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
Nucleic Acids Res., 47, 2019
2YH0
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BU of 2yh0 by Molmil
Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains
Descriptor: SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
2YWK
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BU of 2ywk by Molmil
Crystal structure of RRM-domain derived from human putative RNA-binding protein 11
Descriptor: Putative RNA-binding protein 11
Authors:Kawazoe, M, Takemoto, C, Kaminishi, T, Uchikubo-Kamo, T, Nishino, A, Morita, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-20
Release date:2008-04-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structure of RRM-domain derived from human putative RNA-binding protein 11
To be Published
2YTC
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BU of 2ytc by Molmil
Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22
Descriptor: Pre-mRNA-splicing factor RBM22
Authors:Kasahara, N, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2007-10-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22
To be Published
8RZV
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BU of 8rzv by Molmil
Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
Descriptor: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
Authors:Dunnett, L, Prischi, F.
Deposit date:2024-02-13
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
To Be Published
2YKA
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BU of 2yka by Molmil
RRM domain of mRNA export adaptor REF2-I bound to HVS ORF57 peptide
Descriptor: 52 KDA IMMEDIATE-EARLY PHOSPHOPROTEIN, RNA AND EXPORT FACTOR-BINDING PROTEIN 2
Authors:Tunnicliffe, R.B, Hautbergue, G.M, Kalra, P, Wilson, S.A, Golovanov, A.P.
Deposit date:2011-05-26
Release date:2012-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri Orf57 to the Mammalian Export Adaptor Alyref.
Plos Pathog., 10, 2014
6JVX
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BU of 6jvx by Molmil
Crystal structure of RBM38 in complex with RNA
Descriptor: RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION
Authors:Qian, K, Li, M, Wang, J, Zhang, M, Wang, M.
Deposit date:2019-04-17
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis for mRNA recognition by human RBM38.
Biochem.J., 477, 2020
3B4D
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BU of 3b4d by Molmil
Crystal Structure of Human PABPN1 RRM
Descriptor: Polyadenylate-binding protein 2
Authors:Ge, H, Tong, S, Teng, M, Niu, L.
Deposit date:2007-10-24
Release date:2008-01-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structure and possible dimerization of the single RRM of human PABPN1
Proteins, 71, 2008
3B4M
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BU of 3b4m by Molmil
Crystal Structure of Human PABPN1 RRM
Descriptor: Polyadenylate-binding protein 2
Authors:Ge, H, Zhou, D, Teng, M, Niu, L.
Deposit date:2007-10-24
Release date:2008-01-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal structure and possible dimerization of the single RRM of human PABPN1
Proteins, 71, 2008

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