1H8X
| Domain-swapped Dimer of a Human Pancreatic Ribonuclease Variant | Descriptor: | RIBONUCLEASE 1 | Authors: | Canals, A, Pous, J, Guasch, A, Benito, A, Ribo, M, Vilanova, M, Coll, M. | Deposit date: | 2001-02-16 | Release date: | 2002-02-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structure of an Engineered Domain-Swapped Ribonuclease Dimer and its Implications for the Evolution of Proteins Toward Oligomerization Structure, 9, 2001
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1H1H
| Crystal Structure of Eosinophil Cationic Protein in Complex with 2',5'-ADP at 2.0 A resolution Reveals the Details of the Ribonucleolytic Active site | Descriptor: | ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL CATIONIC PROTEIN | Authors: | Mohan, C.G, Boix, E, Evans, H.R, Nikolovski, Z, Nogues, M.V, Cuchillo, C.M, Acharya, K.R. | Deposit date: | 2002-07-15 | Release date: | 2002-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Eosinophil Cationic Protein in Complex with 2'5'-Adp at 2.0 A Resolution Reveals the Details of the Ribonucleolytic Active Site Biochemistry, 41, 2002
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1GV7
| ARH-I, an angiogenin/RNase A chimera | Descriptor: | ANGIOGENIN, CITRIC ACID | Authors: | Holloway, D.E, Shapiro, R, Hares, M.C, Leonidas, D.D, Acharya, K.R. | Deposit date: | 2002-02-06 | Release date: | 2002-08-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Guest-Host Crosstalk in an Angiogenin-RNase A Chimeric Protein Biochemistry, 41, 2002
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1HBY
| Binding of Phosphate and Pyrophosphate ions at the active site of human angiogenin as revealed by X-ray Crystallography | Descriptor: | ANGIOGENIN, PHOSPHATE ION | Authors: | Leonidas, D.D, Chavali, G.B, Jardine, A.S, Li, S, Shapiro, R, Acharya, K.R. | Deposit date: | 2001-04-21 | Release date: | 2001-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography Protein Sci., 10, 2001
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1HI3
| Eosinophil-derived Neurotoxin (EDN) - Adenosine 2'-5'-Diphosphate Complex | Descriptor: | ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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1HI2
| Eosinophil-derived Neurotoxin (EDN) - Sulphate Complex | Descriptor: | EOSINOPHIL-DERIVED NEUROTOXIN, SULFATE ION | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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1HI5
| Eosinophil-derived Neurotoxin (EDN) - Adenosine-5'-Diphosphate Complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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1HI4
| Eosinophil-derived Neurotoxin (EDN) - Adenosien-3'-5'-Diphosphate Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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3BCP
| Crystal Structure of The Swapped non covalent form of P19A/L28Q/N67D BS-RNase | Descriptor: | Seminal ribonuclease | Authors: | Merlino, A, Ercole, C, Picone, D, Pizzo, E, Mazzarella, L, Sica, F. | Deposit date: | 2007-11-13 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme J.Mol.Biol., 376, 2008
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3BCM
| Crystal Structure of The Unswapped Form of P19A/L28Q/N67D BS-RNase | Descriptor: | PHOSPHATE ION, Seminal ribonuclease | Authors: | Merlino, A, Ercole, C, Picone, D, Pizzo, E, Mazzarella, L, Sica, F. | Deposit date: | 2007-11-13 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme J.Mol.Biol., 376, 2008
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3BCO
| Crystal Structure of The Swapped FOrm of P19A/L28Q/N67D BS-RNase | Descriptor: | Seminal ribonuclease | Authors: | Merlino, A, Ercole, C, Picone, D, Pizzo, E, Mazzarella, L, Sica, F. | Deposit date: | 2007-11-13 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme J.Mol.Biol., 376, 2008
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1J7Z
| Osmolyte Stabilization of Ribonuclease | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1J81
| Osmolyte Stabilization of RNase | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1J80
| Osmolyte Stabilization of RNase | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1IZQ
| F46V mutant of bovine pancreatic ribonuclease A | Descriptor: | RIBONUCLEASE A | Authors: | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | Deposit date: | 2002-10-11 | Release date: | 2003-11-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1J82
| Osmolyte Stabilization of RNase | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1IZR
| F46A mutant of bovine pancreatic ribonuclease A | Descriptor: | RIBONUCLEASE A | Authors: | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | Deposit date: | 2002-10-11 | Release date: | 2003-11-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1IZP
| F46L mutant of bovine pancreatic ribonuclease A | Descriptor: | RIBONUCLEASE A | Authors: | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | Deposit date: | 2002-10-11 | Release date: | 2003-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1JS0
| Crystal Structure of 3D Domain-swapped RNase A Minor Trimer | Descriptor: | RIBONUCLEASE A, SULFATE ION | Authors: | Liu, Y, Gotte, G, Libonati, M, Eisenberg, D. | Deposit date: | 2001-08-15 | Release date: | 2002-03-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of the two 3D domain-swapped RNase A trimers. Protein Sci., 11, 2002
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1K2A
| Modified Form of Eosinophil-derived Neurotoxin | Descriptor: | SULFATE ION, eosinophil-derived neurotoxin | Authors: | Chang, C, Newton, D.L, Rybak, S.M, Wlodawer, A. | Deposit date: | 2001-09-26 | Release date: | 2002-04-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Crystallographic and functional studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel biological activities. J.Mol.Biol., 317, 2002
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1JVV
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3D7B
| The Ribonuclease A- 5'-Deoxy-5'-N-pyrrolidinouridine complex | Descriptor: | 1-(5-deoxy-5-pyrrolidin-1-yl-alpha-L-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione, CITRATE ANION, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-05-21 | Release date: | 2009-02-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J.Med.Chem., 52, 2009
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1JVT
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3D6O
| The RNase A- 5'-Deoxy-5'-N-(ethyl isonipecotatyl)uridine complex | Descriptor: | 1-{5-deoxy-5-[4-(ethoxycarbonyl)piperidin-1-yl]-alpha-L-arabinofuranosyl}pyrimidine-2,4(1H,3H)-dione, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-05-20 | Release date: | 2009-02-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J.Med.Chem., 52, 2009
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1JN4
| The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine | Descriptor: | ADENOSINE-5'-[TRIHYDROGEN DIPHOSPHATE] P'-3'-ESTER WITH 2'-DEOXYURIDINE, Pancreatic Ribonuclease A | Authors: | Jardine, A.M, Leonidas, D.D, Jenkins, J.L, Park, C, Raines, R.T, Acharya, K.R, Shapiro, R. | Deposit date: | 2001-07-23 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin Biochemistry, 40, 2001
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