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3JQL
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Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide Fragment of Amyloid Beta Peptide, Lys-Leu-Val-Phe-Phe-Ala at 1.2 A Resolution
分子名称: Acidic phospholipase A2 3 (Fragment), Amyloid Beta Peptide, CALCIUM ION
著者Mirza, Z, Vikram, G, Singh, N, Sinha, M, Sharma, S, Srinivasan, A, Kaur, P, Singh, T.P.
登録日2009-09-07
公開日2009-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide Fragment of Amyloid Beta Peptide, Lys-Leu-Val-Phe-Phe-Ala at 1.2 A Resolution
To be Published
3JR8
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Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions
分子名称: CALCIUM ION, Phospholipase A2 bothropstoxin-2
著者Borges, R.J, dos Santos, J.I, Fontes, M.R.M.
登録日2009-09-08
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class.
Proteins, 79, 2011
3JTI
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Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution
分子名称: CALCIUM ION, Phospholipase A2 isoform 3, octapeptide from Amyloid beta A4 protein
著者Pandey, N, Mirza, Z, Vikram, G, Singh, N, Bhushan, A, Kaur, P, Srinivasan, A, Sharma, S, Singh, T.P.
登録日2009-09-12
公開日2010-07-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution
To be Published
3L30
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Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine
分子名称: 4,14-dihydro-8H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline-9,10-diol, CALCIUM ION, CHLORIDE ION, ...
著者Naveen, C, Prasanth, G.K, Abhilash, J, Pradeep, M, Ponnuraj, K, Sadasivan, C, Haridas, M.
登録日2009-12-16
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine
To be Published
3MLM
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Crystal structure of Bn IV in complex with myristic acid: A Lys49 myotoxic phospholipase A2 from Bothrops neuwiedi venom
分子名称: BN-IV Lys-49 Phospholipase A2, MYRISTIC ACID, SULFATE ION
著者Delatorre, P, Rocha, B.A.M, Cavada, B.S, Toyama, M.H, Toyama, D, Gadelha, C.A.A.
登録日2010-04-17
公開日2011-05-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of Bn IV in complex with myristic acid: a Lys49 myotoxic phospholipase A2 from Bothrops neuwiedi venom.
Biochimie, 93, 2011
3NJU
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Crystal structure of the complex of group I phospholipase A2 with 4-Methoxy-benzoicacid at 1.4A resolution
分子名称: 4-METHOXYBENZOIC ACID, CALCIUM ION, Phospholipase A2 isoform 3
著者Kaushik, S, Prem Kumar, R, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2010-06-18
公開日2010-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the complex of group I phospholipase A2 with 4-Methoxy-benzoicacid at 1.4A resolution
To be Published
3O4M
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Crystal structure of porcine pancreatic phospholipase A2 in complex with 1,2-dihydroxybenzene
分子名称: CALCIUM ION, CATECHOL, Phospholipase A2, ...
著者Dileep, K.V, Tintu, I, Karthe, P, Mandal, P.K, Haridas, M, Sadasivan, C.
登録日2010-07-27
公開日2010-08-25
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Binding to PLA(2) may contribute to the anti-inflammatory activity of catechol
Chem.Biol.Drug Des., 2011
3OSH
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Crystal Structure of The Complex of Group 1 Phospholipase A2 With Atropin At 1.5 A Resolution
分子名称: (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, CALCIUM ION, Phospholipase A2 isoform 3
著者Shukla, P.K, Kaushik, S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2010-09-09
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of The Complex of Group 1 Phospholipase A2 With Atropin At 1.5 A Resolution
To be Published
3P2P
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ENHANCED ACTIVITY AND ALTERED SPECIFICITY OF PHOSPHOLIPASE A2 BY DELETION OF A SURFACE LOOP
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J.
登録日1989-11-29
公開日1990-01-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop.
Science, 244, 1989
3Q4Y
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Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site
分子名称: CALCIUM ION, ETHANOL, Phospholipase A2 isoform 3
著者Shukla, P.K, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2010-12-26
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site
To be Published
3QLM
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Crystal structure of porcine pancreatic phospholipase A2 in complex with n-hexadecanoic acid
分子名称: CALCIUM ION, PALMITIC ACID, Phospholipase A2, ...
著者Aparna, V, Dileep, K.V, Karthe, P, Mandal, P.K, Sadasivan, C, Haridas, M.
登録日2011-02-03
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and Kinetic assessment.
Chem.Biol.Drug Des., 2012
3QNL
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Crystal structure of PrTX-I complexed to Rosmarinic Acid
分子名称: (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ...
著者dos Santos, J.I, Fontes, M.R.M.
登録日2011-02-08
公開日2012-02-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition.
Plos One, 6, 2011
3R0L
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Crystal structure of crotoxin
分子名称: ACETATE ION, CHLORIDE ION, Crotoxin chain A, ...
著者Saul, F.A, Faure, G.
登録日2011-03-08
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal Structure of Crotoxin Reveals Key Residues Involved in the Stability and Toxicity of This Potent Heterodimeric Beta-Neurotoxin
J.Mol.Biol., 412, 2011
3T0R
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Crystal Structure of MjTX-I, a myotoxic Lys49-phospholipase A2 from Bothrops moojeni
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog 1
著者Salvador, G.H.M, Marchi-Salvador, D.P, Fontes, M.R.M.
登録日2011-07-20
公開日2012-08-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal Structure of MjTX-I, a myotoxic Lys49-phospholipase A2 from Bothrops moojeni
To be Published
3U8B
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Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
登録日2011-10-16
公開日2012-10-17
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8D
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Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
分子名称: (3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid, CALCIUM ION, CHLORIDE ION, ...
著者Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
登録日2011-10-16
公開日2012-10-17
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8H
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Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
分子名称: (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
登録日2011-10-17
公開日2012-10-17
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8I
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Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
登録日2011-10-17
公開日2012-10-17
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3UX7
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Crystal structure of a dimeric myotoxic component of the Vipera ammodytes meridionalis venom reveals determinants of myotoxicity and membrane damaging activity
分子名称: Ammodytin L(1) isoform, SULFATE ION
著者Georgieva, D, Coronado, M, Oberthuer, D, Buck, F, Duhalov, D, Arni, R.K, Genov, N, Betzel, C.
登録日2011-12-04
公開日2012-04-25
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Crystal structure of a dimeric Ser49 PLA(2)-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity.
Mol Biosyst, 8, 2012
3V9M
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Phospholipase ACII4 from Australian King Brown Snake
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Guddat, L.W, Millers, E.K.
登録日2011-12-27
公開日2013-02-13
実験手法X-RAY DIFFRACTION (1.563 Å)
主引用文献Mechanistic studies on the anticoagulant activity of a phospholipase A2 from the venom of the Australian King Brown Snake (Pseudechis australis)
To be Published
3VBZ
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Crystal structure of Taipoxin beta subunit isoform 2
分子名称: Phospholipase A2 homolog, taipoxin beta chain
著者Cendron, L, Micetic, I, Polverino, P, Beltramini, M, Paoli, M.
登録日2012-01-03
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural analysis of trimeric phospholipase A(2) neurotoxin from the Australian taipan snake venom.
Febs J., 279, 2012
3VC0
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Crystal structure of Taipoxin beta subunit isoform 1
分子名称: Phospholipase A2 homolog, taipoxin beta chain
著者Cendron, L, Micetic, I, Polverino de Laureto, P, Beltramini, M, Paoli, M.
登録日2012-01-03
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of trimeric phospholipase A(2) neurotoxin from the Australian taipan snake venom.
Febs J., 279, 2012
4BP2
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CRYSTALLOGRAPHIC REFINEMENT OF BOVINE PRO-PHOSPHOLIPASE A2 AT 1.6 ANGSTROMS RESOLUTION
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2
著者Finzel, B.C, Weber, P.C, Ohlendorf, D.H, Salemme, F.R.
登録日1990-09-07
公開日1991-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic refinement of bovine pro-phospholipase A2 at 1.6 A resolution.
Acta Crystallogr.,Sect.B, 47, 1991
4DBK
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Crystal structure of porcine pancreatic phospholipase A2 complexed with berberine
分子名称: BERBERINE, CALCIUM ION, Phospholipase A2, ...
著者Naveen, C.D, Abhilash, J, Prasanth, G.K, Sadasivan, C, Haridas, M.
登録日2012-01-16
公開日2012-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of porcine pancreatic phospholipase A2 complexed with berberine
To be Published
4DCF
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Structure of MTX-II from Bothrops brazili
分子名称: MTX-II chain A, TETRAETHYLENE GLYCOL
著者Ullah, A, Souza, T.A.C.B, Betzel, C, Murakami, M.T, Arni, R.K.
登録日2012-01-17
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic portrayal of different conformational states of a Lys49 phospholipase A2 homologue: insights into structural determinants for myotoxicity and dimeric configuration.
Int.J.Biol.Macromol., 51, 2012

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