3O4M
Crystal structure of porcine pancreatic phospholipase A2 in complex with 1,2-dihydroxybenzene
Summary for 3O4M
| Related | 2B00 2B03 2B04 3HSW 3L30 3L69 |
| Descriptor | Phospholipase A2, major isoenzyme, CALCIUM ION, CATECHOL, ... (4 entities in total) |
| Functional Keywords | catechol binding, pla2, pancreatic enzyme, disulfide bond, lipid degradation, lipoprotein, metal-binding, palmitate, pyrrolidone carboxylic acid, pancreas, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Sus scrofa (Pig) |
| Cellular location | Secreted: P00592 |
| Total number of polymer chains | 1 |
| Total formula weight | 14199.98 |
| Authors | Dileep, K.V.,Tintu, I.,Karthe, P.,Mandal, P.K.,Haridas, M.,Sadasivan, C. (deposition date: 2010-07-27, release date: 2010-08-25, Last modification date: 2011-11-23) |
| Primary citation | Dileep, K.V.,Haridas, M.,Karthe, P.,Mandal, P.K.,Sadasivan, C.,Tintu, I. Binding to PLA(2) may contribute to the anti-inflammatory activity of catechol Chem.Biol.Drug Des., 2011 PubMed: 21995306 DOI: 110.1111/j.1747-0285.2011.01258.x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
