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2KNF
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Solution structure and functional characterization of human plasminogen kringle 5
分子名称: Plasminogen
著者Battistel, M.D, Grishaev, A, An, S.A, Castellino, F.J, Llinas, M.
登録日2009-08-21
公開日2009-10-27
最終更新日2021-10-13
実験手法SOLUTION NMR
主引用文献Solution structure and functional characterization of human plasminogen kringle 5.
Biochemistry, 48, 2009
3E6P
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Crystal structure of human meizothrombin desF1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-PHENYLALANYL-N-[(1S)-4-{[(Z)-AMINO(IMINO)METHYL]AMINO}-1-(CHLOROACETYL)BUTYL]-L-PROLINAMIDE, Prothrombin, ...
著者Papaconstantinou, M.E, Gandhi, P, Chen, Z, Bah, A, Di Cera, E.
登録日2008-08-15
公開日2008-11-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Na(+) binding to meizothrombin desF1.
Cell.Mol.Life Sci., 65, 2008
3BT1
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Structure of urokinase receptor, urokinase and vitronectin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
著者Huang, M.
登録日2007-12-27
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3BT2
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Structure of urokinase receptor, urokinase and vitronectin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ...
著者Huang, M.
登録日2007-12-27
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
2QJ2
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A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
分子名称: Hepatocyte growth factor, SULFATE ION
著者Tolbert, W.D, Daugherty, J, Gao, C.-F, Xe, Q, Miranti, C, Gherardi, E, Vande Woude, G, Xu, H.E.
登録日2007-07-06
公開日2007-09-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QJ4
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A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
分子名称: Hepatocyte growth factor, SULFATE ION
著者Tolbert, W.D, Daugherty, J, Gao, C.-F, Xe, Q, Miranti, C, Gherardi, E, Vande Woude, G, Xu, H.E.
登録日2007-07-06
公開日2007-09-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist
Proc.Natl.Acad.Sci.Usa, 104, 2007
2I9B
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Crystal structure of ATF-urokinase receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Urokinase plasminogen activator surface receptor, ...
著者Lubkowski, J, Barinka, C.
登録日2006-09-05
公開日2007-01-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol., 363, 2006
2FEB
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NMR Solution Structure, Dynamics and Binding Properties of the Kringle IV Type 8 module of apolipoprotein(a)
分子名称: Apolipoprotein(a)
著者Chitayat, S, Kanelis, V, Koschinsky, M.L, Smith, S.P.
登録日2005-12-15
公開日2006-12-26
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a).
Biochemistry, 46, 2007
2DOI
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The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM
分子名称: Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
著者Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H.
登録日2006-04-29
公開日2006-12-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2DOH
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The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group A streptococcal surface protein PAM
分子名称: 1,4-DIETHYLENE DIOXIDE, Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
著者Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H.
登録日2006-04-29
公開日2006-12-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2I9A
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Crystal structure of the free aminoterminal fragment of urokinase type plasminogen activator (ATF)
分子名称: PHOSPHATE ION, Urokinase-type plasminogen activator
著者Lubkowski, J, Barinka, C.
登録日2006-09-05
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol., 363, 2006
2FD6
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Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A
分子名称: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ...
著者Huang, M, Huai, Q, Li, Y.
登録日2005-12-13
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of human urokinase plasminogen activator in complex with its receptor
Science, 311, 2006
1NL1
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BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM ION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huang, M, Huang, G, Furie, B, Seaton, B, Furie, B.C.
登録日2003-01-06
公開日2003-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
Nat.Struct.Biol., 10, 2003
1NL2
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BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM AND LYSOPHOSPHOTIDYLSERINE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huang, M, Huang, G, Furie, B, Seaton, B, Furie, B.C.
登録日2003-01-06
公開日2003-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
Nat.Struct.Biol., 10, 2003
1JFN
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SOLUTION STRUCTURE OF HUMAN APOLIPOPROTEIN(A) KRINGLE IV TYPE 6
分子名称: APOLIPOPROTEIN A, KIV-T6
著者Maderegger, B, Bermel, W, Hrzenjak, A, Kostner, G.M, Sterk, H.
登録日2001-06-21
公開日2002-06-28
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of human apolipoprotein(a) kringle IV type 6.
Biochemistry, 41, 2002
1KI0
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The X-ray Structure of Human Angiostatin
分子名称: ANGIOSTATIN, BICINE
著者Abad, M.C, Arni, R.K, Grella, D.K, Castellino, F.J, Tulinsky, A, Geiger, J.H.
登録日2001-12-02
公開日2002-05-29
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
J.Mol.Biol., 318, 2002
1GP9
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A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEPATOCYTE GROWTH FACTOR
著者Watanabe, K, Chirgadze, D.Y, Lietha, D, Gherardi, E, Blundell, T.L.
登録日2001-10-31
公開日2001-11-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping
J.Mol.Biol., 319, 2002
1GMN
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CRYSTAL STRUCTURES OF NK1-HEPARIN COMPLEXES REVEAL THE BASIS FOR NK1 ACTIVITY AND ENABLE ENGINEERING OF POTENT AGONISTS OF THE MET RECEPTOR
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEPATOCYTE GROWTH FACTOR
著者Lietha, D, Chirgadze, D.Y, Mulloy, B, Blundell, T.L, Gherardi, E.
登録日2001-09-19
公開日2001-10-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor
Embo J., 20, 2001
1GMO
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CRYSTAL STRUCTURES OF NK1-HEPARIN COMPLEXES REVEAL THE BASIS FOR NK1 ACTIVITY AND ENABLE ENGINEERING OF POTENT AGONISTS OF THE MET RECEPTOR
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ...
著者Lietha, D, Chirgadze, D.Y, Mulloy, B, Blundell, T.L, Gherardi, E.
登録日2001-09-20
公開日2001-10-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor
Embo J., 20, 2001
1I5K
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STRUCTURE AND BINDING DETERMINANTS OF THE RECOMBINANT KRINGLE-2 DOMAIN OF HUMAN PLASMINOGEN TO AN INTERNAL PEPTIDE FROM A GROUP A STREPTOCOCCAL SURFACE PROTEIN
分子名称: M PROTEIN, PLASMINOGEN
著者Rios-Steiner, J.L, Schenone, M, Mochalkin, I, Tulinsky, A, Castellino, F.J.
登録日2001-02-27
公開日2001-08-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.
J.Mol.Biol., 308, 2001
1I71
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HIGH RESOLUTION CRYSTAL STRUCTURE OF APOLIPOPROTEIN(A) KRINGLE IV TYPE 7: INSIGHTS INTO LIGAND BINDING
分子名称: APOLIPOPROTEIN(A), SULFATE ION
著者Ye, Q, Rahman, M.N, Koschinsky, M.L, Jia, Z.
登録日2001-03-07
公開日2001-06-13
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献High-resolution crystal structure of apolipoprotein(a) kringle IV type 7: insights into ligand binding.
Protein Sci., 10, 2001
1B2I
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KRINGLE 2 DOMAIN OF HUMAN PLASMINOGEN: NMR SOLUTION STRUCTURE OF TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID (AMCHA) COMPLEX
分子名称: PROTEIN (PLASMINOGEN), TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
著者Marti, D.N, Schaller, J, Llinas, M.
登録日1999-09-24
公開日1999-11-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the plasminogen kringle 2-AMCHA complex: 3(1)-helix in homologous domains.
Biochemistry, 38, 1999
1KIV
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RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)
分子名称: APOLIPOPROTEIN A
著者Mochalkin, I, Tulinsky, A, Scanu, A.
登録日1998-08-26
公開日1999-05-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
3KIV
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RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)
分子名称: 6-AMINOHEXANOIC ACID, APOLIPOPROTEIN
著者Mochalkin, I, Tulinsky, A, Scanu, A.
登録日1998-09-08
公開日1999-05-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
4KIV
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RECOMBINANT KRINGLE IV-10/W72R MUTANT OF HUMAN APOLIPOPROTEIN(A)
分子名称: APOLIPOPROTEIN
著者Mochalkin, I, Tulinsky, A, Scanu, A.
登録日1998-08-26
公開日1999-05-18
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999

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