1GP9
A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping
Summary for 1GP9
| Entry DOI | 10.2210/pdb1gp9/pdb |
| Related | 1BHT 1GMN 1GMO 1NK1 2HGF |
| Descriptor | HEPATOCYTE GROWTH FACTOR, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total) |
| Functional Keywords | hormone/growth factor, hgf/sf, nk1, met, domain swapping, protein engineering, growth factor, kringle, glycoprotein, hormone-growth factor complex |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 4 |
| Total formula weight | 82508.44 |
| Authors | Watanabe, K.,Chirgadze, D.Y.,Lietha, D.,Gherardi, E.,Blundell, T.L. (deposition date: 2001-10-31, release date: 2001-11-19, Last modification date: 2023-12-13) |
| Primary citation | Watanabe, K.,Chirgadze, D.Y.,Lietha, D.,De Jonge, H.,Blundell, T.L.,Gherardi, E. A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping J.Mol.Biol., 319:283-, 2002 Cited by PubMed: 12051906DOI: 10.1016/S0022-2836(02)00199-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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