1GP9

A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	HEPATOCYTE GROWTH FACTOR	polymer	177	20329.2	4	UniProt (P14210) Pfam (PF00024) Pfam (PF00051)	HOMO SAPIENS (HUMAN)	SCATTER FACTOR, SF, HEPATOPOEITIN A
2	E, F, G, H, I (A, B, C, D)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	5	Chemie (EPE)
3	J, K, L, M (A, B, C, D)	water	water		18.0	156	Chemie (HOH)

Sequence modifications

A, B, C, D: 34 - 39 (PDB: 1GP9)
A, B, C, D: 40 - 210 (UniProt: P14210)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	81316.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1191.5
All*	Total formula weight	82508.4

*Water molecules are not included.