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8S9P
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1:1:1 agrin/LRP4/MuSK complex
分子名称: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
著者Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
登録日2023-03-29
公開日2023-05-17
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
7QE9
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S)
分子名称: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
著者Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
登録日2021-12-01
公開日2022-03-30
最終更新日2022-04-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7QE8
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
分子名称: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
著者Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
登録日2021-12-01
公開日2022-03-30
最終更新日2022-04-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7E50
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Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
分子名称: AAEL006007-PA, GLYCEROL, Plasminogen, ...
著者Varsha, A.W, Jobichen, C, Mok, Y.K.
登録日2021-02-16
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
6KBR
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Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
分子名称: GLYCEROL, K41043, Kallikrein-4
著者Kawaguchi, Y, Nishimiya, D.
登録日2019-06-26
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
5YHN
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Solution structure of the LEKTI Domain 4
分子名称: cDNA FLJ60407, highly similar to Serine protease inhibitor Kazal-type 5
著者Mok, Y.K, Ramesh, K.
登録日2017-09-29
公開日2018-08-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity.
Structure, 26, 2018
2N71
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NMR structure of CmPI-II, a serin protease inhibitor isolated from mollusk Cenchitis muricatus
分子名称: Protease inhibitor 2
著者Cabrera-Munoz, A, Rojas, L, Alonso del Rivero Antigua, M, Pires, J.
登録日2015-09-01
公開日2016-09-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR structure of CmPI-II, a non-classical Kazal protease inhibitor: Understanding its conformational dynamics and subtilisin A inhibition.
J.Struct.Biol., 206, 2019
5DAE
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Kazal type inhibitor from salivary glands of Aedes aegypti mosquito
分子名称: AAEL006007-PA
著者Torquato, R.J.S, Pereira, P.J.B, Tanaka, A.S.
登録日2015-08-19
公開日2016-09-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2N52
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The solution structure of the kallikrein inhibitor SPINK6
分子名称: Serine protease inhibitor Kazal-type 6
著者Grotzinger, J.
登録日2015-07-06
公開日2016-03-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The solution structure of the kallikrein-related peptidases inhibitor SPINK6.
Biochem.Biophys.Res.Commun., 471, 2016
2M5X
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Novel method of protein purification for structural research. Example of ultra high resolution structure of SPI-2 inhibitor by X-ray and NMR spectroscopy.
分子名称: Silk protease inhibitor 2
著者Lenarcic Zivkovic, M, Dvornyk, A, Kludkiewicz, B, Kopera, E, Zagorski-Ostoja, W, Grzelak, K, Zhukov, I, Bal, W.
登録日2013-03-12
公開日2014-03-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
4HGU
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Crystal Structure of Galleria mellonella Silk Protease Inhibitor 2
分子名称: SODIUM ION, Silk protease inhibitor 2
著者Krzywda, S, Jaskolski, M, Dvornyk, A, Kludkiewicz, B, Grzelak, K, Zagorski, W, Bal, W, Kopera, E.
登録日2012-10-08
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
2LEO
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Solution structure of esophageal cancer-related gene 2
分子名称: Serine protease inhibitor Kazal-type 7
著者Feng, Y, Geng, Y, Wang, J.
登録日2011-06-20
公開日2012-05-30
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR structure note: human esophageal cancer-related gene 2
J.Biomol.Nmr, 53, 2012
2KMO
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Solution structure of native Leech-derived tryptase inhibitor, LDTI
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMP
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Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMQ
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Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2V53
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Crystal structure of a SPARC-collagen complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COLLAGEN ALPHA-1(III) CHAIN, ...
著者Hohenester, E, Sasaki, T, Giudici, C, Farndale, R.W, Bachinger, H.P.
登録日2008-10-01
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis of Sequence-Specific Collagen Recognition by Sparc.
Proc.Natl.Acad.Sci.USA, 105, 2008
2JXD
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BU of 2jxd by Molmil
NMR structure of human Serine protease inhibitor Kazal type II (SPINK2)
分子名称: Serine protease inhibitor Kazal-type 2
著者Chen, T, Lee, T.-R, Lyu, P.-C.
登録日2007-11-15
公開日2008-11-18
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Identification of trypsin-inhibitory site and structure determination of human SPINK2 serine proteinase inhibitor
Proteins, 77, 2009
2NU0
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Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I
分子名称: Ovomucoid, Streptogrisin B, Protease B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I
To be Published
2NU1
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Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
分子名称: Ovomucoid, Streptogrisin B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
To be Published
2NU4
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
分子名称: Ovomucoid, Streptogrisin B, Proteinase B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU3
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
分子名称: Ovomucoid, Streptogrisin B, Proteinase B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU2
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
分子名称: Ovomucoid, Streptogrisin B, Protease B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2GKR
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Crystal structure of the N-terminally truncated OMTKY3-del(1-5)
分子名称: CHLORIDE ION, Ovomucoid
著者Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-04-03
公開日2007-02-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
2GKV
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Crystal structure of the SGPB:P14'-Ala32 OMTKY3-del(1-5) complex
分子名称: Ovomucoid, Streptogrisin B
著者Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-04-03
公開日2007-02-13
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007

 

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