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5AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE Descriptor: PHENOL, PROTEIN (INSULIN) Authors: O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. Deposit date: 1998-12-29 Release date: 2000-02-28 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
4INS	THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION Descriptor: INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION Authors: Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. Deposit date: 1989-07-10 Release date: 1990-04-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos.Trans.R.Soc.London,Ser.B, 319, 1988
4IHN	High Resolution Insulin by Langmuir-Blodgett Modified Hanging Drop Vapour Diffusion Descriptor: Insulin A chain, Insulin B chain Authors: Belmonte, L, Pechkova, E, Bragazzi, N, Nicolini, C. Deposit date: 2012-12-19 Release date: 2013-12-25 Method: X-RAY DIFFRACTION (1.16 Å) Cite: A Review Of The Strategies For Obtaining High Quality Crystals Utilizing Nanotechnologies And Space To be Published
6Q8Q	Bovine Insulin under 2 kbar of argon Descriptor: ARGON, Insulin Authors: Prange, T, Carpentier, P. Deposit date: 2018-12-16 Release date: 2020-01-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Argon-labelling protein crystals by high pressure cooling at 2 kbar To be published
4IYD	Insulin glargine crystal structure 1 Descriptor: Insulin A chain, Insulin B chain Authors: Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A. Deposit date: 2013-01-28 Release date: 2014-02-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference to be published
2C8R	insuline(60sec) and UV laser excited fluorescence Descriptor: INSULIN A CHAIN, INSULIN B CHAIN Authors: Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. Deposit date: 2005-12-06 Release date: 2006-03-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
2C8Q	insuline(1sec) and UV laser excited fluorescence Descriptor: INSULIN A CHAIN, INSULIN B CHAIN Authors: Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. Deposit date: 2005-12-06 Release date: 2006-03-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
4IUZ	High resolution crystal structure of racemic ester insulin Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... Authors: Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. Deposit date: 2013-01-22 Release date: 2013-02-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
4IYF	Insulin glargine crystal structure 2 Descriptor: Insulin A chain, Insulin B chain Authors: Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A. Deposit date: 2013-01-28 Release date: 2014-02-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference to be published
1XDA	STRUCTURE OF INSULIN Descriptor: CHLORIDE ION, FATTY ACID ACYLATED INSULIN, MYRISTIC ACID, ... Authors: Whittingham, J.L, Havelund, S, Jonassen, I. Deposit date: 1996-12-18 Release date: 1997-07-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a prolonged-acting insulin with albumin-binding properties. Biochemistry, 36, 1997
6QRH	High pressure structure of bovine insulin (100 MPa) Descriptor: Insulin Authors: Kurpiewska, K, Milaczewska, A, Lewinski, K. Deposit date: 2019-02-19 Release date: 2019-02-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.152 Å) Cite: Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
6QRK	High pressure structure of bovine insulin (200 MPa) Descriptor: Insulin Authors: Kurpiewska, K, Milaczewska, A, Lewinski, K. Deposit date: 2019-02-19 Release date: 2019-03-06 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.102 Å) Cite: Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
5AZZ	Crystal structure of seleno-insulin Descriptor: Insulin A chain, Insulin B chain Authors: Watanabe, S, Okumura, M, Arai, K, Takei, T, Asahina, Y, Hojo, H, Iwaoka, M, Inaba, K. Deposit date: 2015-10-23 Release date: 2017-05-03 Last modified: 2017-06-14 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue. Angew. Chem. Int. Ed. Engl., 56, 2017
6QQ7	Bovine insulin at ambient pressure Descriptor: Insulin Authors: Kurpiewska, K, Milaczewska, A, Lewinski, K. Deposit date: 2019-02-18 Release date: 2019-02-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
6QQG	High pressure structure of bovine insulin (60 MPa) Descriptor: Insulin Authors: Kurpiewska, K, Milaczewska, A, Lewinski, K. Deposit date: 2019-02-18 Release date: 2019-03-06 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.149 Å) Cite: Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
5BTS	Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin Descriptor: Insulin A chain, Insulin B chain Authors: Norrman, M, Hjorth, C.F. Deposit date: 2015-06-03 Release date: 2016-03-09 Last modified: 2019-02-20 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin. J.Pharm.Sci., 105, 2016
5BOQ	Human insulin with intra-chain chemical crosslink between modified B24 and B29 Descriptor: Insulin, SULFATE ION Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2015-05-27 Release date: 2016-02-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
5BPO	Human insulin with intra-chain chemical crosslink between modified B27 and B29 Descriptor: Insulin Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2015-05-28 Release date: 2016-02-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
1XW7	Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama Descriptor: CHLORIDE ION, Insulin, PHENOL, ... Authors: Wan, Z.L, Huang, K, Xu, B, Chu, Y.C, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A. Deposit date: 2004-10-29 Release date: 2005-04-12 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin wakayama Biochemistry, 44, 2005
1XGL	HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES Descriptor: INSULIN Authors: Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. Deposit date: 1996-10-10 Release date: 1997-04-01 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Structure of a protein in a kinetic trap. Nat.Struct.Biol., 2, 1995
2EFA	Neutron crystal structure of cubic insulin at pD6.6 Descriptor: Insulin Authors: Ishikawa, T, Tanaka, I, Niimura, N. Deposit date: 2007-02-22 Release date: 2008-01-22 Last modified: 2023-10-25 Method: NEUTRON DIFFRACTION (2.7 Å) Cite: A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6 Chem.Phys., 345, 2008
5CO6	Crystal structure of human zinc insulin at pH 6.5 Descriptor: CHLORIDE ION, Insulin, MAGNESIUM ION, ... Authors: Lima, L.M.T.R, PALMIERI, L.C. Deposit date: 2015-07-19 Release date: 2015-08-26 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of human zinc insulin at pH 6.5 To Be Published
5CO9	Crystal structure of human zinc insulin at pH 6.5 Descriptor: CHLORIDE ION, Insulin, ZINC ION Authors: Lima, L.M.T.R, Palmieri, L.C. Deposit date: 2015-07-20 Release date: 2015-08-26 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Crystal structure of human zinc insulin at pH 6.5 To Be Published
6S34	Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution Descriptor: 1,2-ETHANEDIOL, Insulin A chain, Insulin B chain Authors: Johansson, E. Deposit date: 2019-06-24 Release date: 2019-07-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution Not Published
5CO2	Crystalization of human zinc insulin at pH 5.5 Descriptor: CHLORIDE ION, Insulin, ZINC ION Authors: Lima, L.M.T.R, Palmieri, L.C. Deposit date: 2015-07-19 Release date: 2015-08-26 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of human zinc insulin at pH 5.5 To Be Published

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