3W7Y
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1SF1
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1TRZ
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3ZI3
| Crystal structure of the B24His-insulin - human analogue | 分子名称: | INSULIN, SULFATE ION | 著者 | Zakova, L, Kletvikova, E, Veverka, V, Lepsik, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. | 登録日 | 2013-01-02 | 公開日 | 2013-03-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Integrity of the B24 Site in Human Insulin is Important for Hormone Functionality J.Biol.Chem., 288, 2013
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3W7Z
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1TGR
| Crystal Structure of mini-IGF-1(2) | 分子名称: | Insulin-like growth factor IA | 著者 | Liang, D.C, Yun, C.H, Chang, W.R. | 登録日 | 2004-05-29 | 公開日 | 2004-12-28 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | 1.42A crystal structure of mini-IGF-1(2): an analysis of the disulfide isomerization property and receptor binding property of IGF-1 based on the three-dimensional structure Biochem.Biophys.Res.Commun., 326, 2004
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4AIY
| R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE | 分子名称: | PHENOL, PROTEIN (INSULIN) | 著者 | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | 登録日 | 1998-12-29 | 公開日 | 2000-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
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4AJX
| Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | 分子名称: | IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ... | 著者 | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | 登録日 | 2012-02-20 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
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1T1P
| NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES | 分子名称: | Insulin, insulin | 著者 | Huang, K, Xu, B, Hu, S.Q, Chu, Y.C, Hua, Q.X, Whittaker, J, Nakagawa, S.H, De Meyts, P, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2004-04-16 | 公開日 | 2004-08-10 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | How Insulin Binds: the B-Chain alpha-Helix Contacts the L1 beta-Helix of the Insulin Receptor. J.Mol.Biol., 341, 2004
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3TT8
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3V1G
| Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | 著者 | Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. | 登録日 | 2011-12-09 | 公開日 | 2012-12-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Forestalling insulin fibrillation by insertion of a
chiral clamp mechanism-based application of protein engineering to global health To be Published
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4AKJ
| Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | 著者 | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | 登録日 | 2012-02-23 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
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1UZ9
| Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins. | 分子名称: | (2S)-2-AMINO-6-({(4R)-4-[(10R,13S)-10,13-DIMETHYL-3-OXOHEXADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]PENTANOYL}AMINO)HEXANOIC ACID, CHLORIDE ION, INSULIN, ... | 著者 | Whittingham, J.L, Jonassen, I, Havelund, S, Roberts, S.M, Dodson, E.J, Verma, C.S, Wilkinson, A.J, Dodson, G.G. | 登録日 | 2004-03-08 | 公開日 | 2005-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystallographic and Solution Studies of N-Lithocholyl Insulin: A New Generation of Prolonged-Acting Human Insulins Biochemistry, 43, 2004
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1SJU
| MINI-PROINSULIN, SINGLE CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP AND PEPTIDE BOND BETWEEN LYS B 29 AND GLY A 1, NMR, 20 STRUCTURES | 分子名称: | PROINSULIN | 著者 | Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 1997-10-09 | 公開日 | 1998-03-18 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures. J.Mol.Biol., 277, 1998
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7RKD
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7S4Y
| Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X. | 登録日 | 2021-09-09 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Serial macromolecular crystallography at ALBA Synchrotron Light Source. J.Synchrotron Radiat., 29, 2022
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4EX1
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-04-29 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.657 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EY9
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-05-01 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.471 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EYD
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-05-01 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.471 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EWZ
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-04-29 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4E7U
| The structure of T3R3 bovine insulin | 分子名称: | Insulin A chain, Insulin B chain, THIOCYANATE ION, ... | 著者 | Harris, P, Frankaer, C.G, Knudsen, M.V. | 登録日 | 2012-03-19 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012
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4EWW
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-04-28 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EX0
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-04-29 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EYN
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-05-01 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.532 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4F0O
| Human Insulin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | 登録日 | 2012-05-04 | 公開日 | 2013-05-08 | 最終更新日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (1.672 Å) | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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