6CWS
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4UAI
| Crystal structure of CXCL12 in complex with inhibitor | Descriptor: | 1-phenyl-3-[4-(1H-tetrazol-5-yl)phenyl]urea, SULFATE ION, Stromal cell-derived factor 1 | Authors: | Smith, E.W, Chen, Y. | Deposit date: | 2014-08-09 | Release date: | 2014-11-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine. J.Med.Chem., 57, 2014
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5OB5
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3N52
| crystal Structure analysis of MIP2 | Descriptor: | C-X-C motif chemokine 2 | Authors: | Rajasekaran, D. | Deposit date: | 2010-05-24 | Release date: | 2011-06-08 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects. Biochemistry, 51, 2012
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7JNY
| Crystal structure of CXCL13 | Descriptor: | C-X-C motif chemokine 13 | Authors: | Rosenberg Jr, E.M, Rajasekaran, D, Murphy, J.W, Pantouris, G, Lolis, E.J. | Deposit date: | 2020-08-05 | Release date: | 2020-10-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity. Acta Crystallogr D Struct Biol, 76, 2020
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6VGJ
| N-terminal variant of CXCL13 | Descriptor: | C-X-C motif chemokine 13 | Authors: | Rosenberg Jr, E.M, Lolis, E.J. | Deposit date: | 2020-01-08 | Release date: | 2020-10-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity. Acta Crystallogr D Struct Biol, 76, 2020
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4DN4
| Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a | Descriptor: | ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ... | Authors: | Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. | Deposit date: | 2012-02-08 | Release date: | 2012-10-03 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
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5IZB
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3TN2
| structure analysis of MIP1-beta P8A | Descriptor: | C-C motif chemokine 4, ZINC ION | Authors: | Guo, Q, Tang, W.J. | Deposit date: | 2011-09-01 | Release date: | 2012-09-05 | Last modified: | 2018-08-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
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5D65
| X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-C motif chemokine 3, CHLORIDE ION, ... | Authors: | Liang, W.G, Hwang, D.Y, Zulueta, M.M, Hung, S.C, Tang, W. | Deposit date: | 2015-08-11 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
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5D14
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1VMC
| STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA) | Descriptor: | Stromal cell-derived factor 1 | Authors: | Gozansky, E.K, Clore, G.M. | Deposit date: | 2004-09-20 | Release date: | 2005-03-01 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha. J.Mol.Biol., 345, 2005
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1VMP
| STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II | Descriptor: | PROTEIN (ANTI-HIV CHEMOKINE MIP VII) | Authors: | Liwang, A.C, Wang, Z.-X, Sun, Y, Peiper, S.C, Liwang, P.J. | Deposit date: | 1999-03-25 | Release date: | 1999-11-24 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The solution structure of the anti-HIV chemokine vMIP-II. Protein Sci., 8, 1999
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5DNF
| Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, C-C motif chemokine 5, ... | Authors: | Liang, W.G, Tang, W. | Deposit date: | 2015-09-10 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.549 Å) | Cite: | Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
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6WZK
| LY3041658 Fab bound to CXCL3 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, C-X-C motif chemokine 3, ... | Authors: | Durbin, J.D, Druzina, Z. | Deposit date: | 2020-05-14 | Release date: | 2020-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody. Mabs, 12
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1LV9
| CXCR3 Binding Chemokine IP-10/CXCL10 | Descriptor: | Small inducible cytokine B10 | Authors: | Booth, V, Keizer, D.W, Kamphuis, M.B, Clark-Lewis, I, Sykes, B.D. | Deposit date: | 2002-05-27 | Release date: | 2002-09-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions. Biochemistry, 41, 2002
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1MI2
| SOLUTION STRUCTURE OF MURINE MACROPHAGE INFLAMMATORY PROTEIN-2, NMR, 20 STRUCTURES | Descriptor: | MACROPHAGE INFLAMMATORY PROTEIN-2 | Authors: | Shao, W, Jerva, L.F, West, J, Lolis, E, Schweitzer, B.I. | Deposit date: | 1997-10-24 | Release date: | 1998-04-29 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of murine macrophage inflammatory protein-2. Biochemistry, 37, 1998
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6AEZ
| Crystal structure of human CCL5 trimer | Descriptor: | C-C motif chemokine 5, SULFATE ION | Authors: | Chen, Y.C, Li, K.M, Chen, P.J, Zarivach, R, Sun, Y.J, Sue, S.C. | Deposit date: | 2018-08-07 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5. J.Mol.Biol., 432, 2020
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4LMQ
| Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12 | Descriptor: | Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain | Authors: | Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N. | Deposit date: | 2013-07-10 | Release date: | 2013-08-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.773 Å) | Cite: | Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12. Clin.Cancer Res., 19, 2013
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6EHZ
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4MHE
| Crystal structure of CC-chemokine 18 | Descriptor: | ACETATE ION, C-C motif chemokine 18 | Authors: | Liang, W.G, Tang, W.-J. | Deposit date: | 2013-08-29 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
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6SHR
| X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A | Descriptor: | Stromal cell-derived factor 1 | Authors: | Jugnarain, V.M, Mitchell, E, Forsyth, T, Michael, H, Cortes, S, Tillier, B. | Deposit date: | 2019-08-08 | Release date: | 2020-08-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.745 Å) | Cite: | X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A To Be Published
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6FGP
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5EKI
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6C6D
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