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1PL1
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Crystal structure of human glutathione transferase (GST) A1-1 in complex with a decarboxy-glutathione
Descriptor: CHLORIDE ION, Glutathione S-transferase A1, N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE
Authors:Grahn, E, Jakobsson, E, Gustafsson, A, Grehn, L, Olin, B, Wahlberg, M, Madsen, D, Kleywegt, G.J, Mannervik, B.
Deposit date:2003-06-06
Release date:2004-06-22
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PL2
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Crystal structure of human glutathione transferase (GST) A1-1 T68E mutant in complex with decarboxy-glutathione
Descriptor: CHLORIDE ION, Glutathione S-transferase A1, N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE
Authors:Grahn, E, Jakobsson, E, Gustafsson, A, Grehn, L, Olin, B, Wahlberg, M, Madsen, D, Kleywegt, G.J, Mannervik, B.
Deposit date:2003-06-06
Release date:2004-06-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PMT
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GLUTATHIONE TRANSFERASE FROM PROTEUS MIRABILIS
Descriptor: GLUTATHIONE, GLUTATHIONE TRANSFERASE
Authors:Rossjohn, J, Polekhina, G, Feil, S.C, Allocati, N, Masulli, M, Diilio, C, Parker, M.W.
Deposit date:1998-03-23
Release date:1999-04-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications.
Structure, 6, 1998
1PN9
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BU of 1pn9 by Molmil
Crystal structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae
Descriptor: Glutathione S-transferase 1-6, S-HEXYLGLUTATHIONE
Authors:Chen, L, Hall, P.R, Zhou, X.E, Ranson, H, Hemingway, J, Meehan, E.J.
Deposit date:2003-06-12
Release date:2003-12-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae.
Acta Crystallogr.,Sect.D, 59, 2003
1TDI
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BU of 1tdi by Molmil
Crystal Structure of hGSTA3-3 in Complex with Glutathione
Descriptor: GLUTATHIONE, Glutathione S-transferase A3-3
Authors:Gu, Y, Guo, J, Pal, A, Pan, S.S, Zimniak, P, Singh, S.V, Ji, X.
Deposit date:2004-05-22
Release date:2005-01-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.
Biochemistry, 43, 2004
1U3I
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BU of 1u3i by Molmil
Crystal structure of glutathione S-tranferase from Schistosoma mansoni
Descriptor: GLUTATHIONE, Glutathione S-transferase 28 kDa
Authors:Chomilier, J, Vaney, M.C, Labesse, G, Trottein, F, Capron, A, Mormon, J.-P.
Deposit date:2004-07-22
Release date:2005-07-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of Schistosoma mansoni glutathione S-transferase
To be Published
1USB
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BU of 1usb by Molmil
Rational design of a novel enzyme - efficient thioester hydrolysis enabled by the incorporation of a single His residue into human glutathione transferase A1-1
Descriptor: CHLORIDE ION, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A1, ...
Authors:Jakobsson, E, Kleywegt, G.J.
Deposit date:2003-11-20
Release date:2004-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Incorporation of a Single His Residue by Rational Design Enables Thiol-Ester Hydrolysis by Human Glutathione Transferase A1-1
Proc.Natl.Acad.Sci.USA, 101, 2004
1V2A
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Glutathione S-transferase 1-6 from Anopheles dirus species B
Descriptor: GLUTATHIONE SULFONIC ACID, glutathione transferase gst1-6
Authors:Oakley, A.J.
Deposit date:2003-10-10
Release date:2003-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme.
Biochem.J., 388, 2005
1VF1
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cGSTA1-1 in complex with glutathione
Descriptor: GLUTATHIONE, Glutathione S-transferase 3
Authors:Lin, S.C, Lo, Y.C, Tam, M.F, Liaw, Y.C.
Deposit date:2004-04-07
Release date:2005-08-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structures of chicken glutathione S-transferase A1-1
To be Published
1VF2
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cGSTA1-1 in complex with S-hexyl-glutathione
Descriptor: Glutathione S-transferase 3, S-HEXYLGLUTATHIONE, ZINC ION
Authors:Lin, S.C, Lo, Y.C, Tam, M.F, Liaw, Y.C.
Deposit date:2004-04-07
Release date:2005-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of chicken glutathione S-transferase A1-1
To be Published
1VF3
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cGSTA1-1 in complex with glutathione conjugate of CDNB
Descriptor: ACETIC ACID, GLUTATHIONE S-(2,4 DINITROBENZENE), Glutathione S-transferase 3
Authors:Lin, S.C, Lo, Y.C, Tam, M.F, Liaw, Y.C.
Deposit date:2004-04-07
Release date:2005-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of chicken glutathione S-transferase A1-1
To be Published
1VF4
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cGSTA1-1 apo form
Descriptor: ACETIC ACID, Glutathione S-transferase 3
Authors:Lin, S.C, Lo, Y.C, Tam, M.F, Liaw, Y.C.
Deposit date:2004-04-08
Release date:2005-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of chicken glutathione S-transferase A1-1
To be Published
1XW5
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BU of 1xw5 by Molmil
Human glutathione s-transferase M2-2 (E.C.2.5.1.18)complexed with glutathione, monoclinic crystal form
Descriptor: GLUTATHIONE, Glutathione S-transferase Mu 2
Authors:Patskovska, L.N, Patskovsky, Y.V, Almo, S.C, Listowsky, I.
Deposit date:2004-10-29
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Perturbation of the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
1XW6
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1.9 angstrom resolution structure of human glutathione S-transferase M1A-1A complexed with glutathione
Descriptor: GLUTATHIONE, Glutathione S-transferase Mu 1
Authors:Patskovsky, Y, Patskovska, L, Almo, S.C, Listowsky, I.
Deposit date:2004-10-29
Release date:2004-12-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
1XWG
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BU of 1xwg by Molmil
Human GST A1-1 T68E mutant
Descriptor: Glutathione S-transferase A1
Authors:Grahn, E, Jakobsson, E, Gustafsson, A, Novotny, M, Grehn, L, Olin, B, Madsen, D, Wahlberg, M, Mannervik, B, Kleywegt, G.J.
Deposit date:2004-11-01
Release date:2005-11-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1XWK
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2.3 angstrom resolution crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-S-dinitrobenzene
Descriptor: GLUTATHIONE S-(2,4 DINITROBENZENE), Glutathione S-transferase Mu 1
Authors:Patskovsky, Y, Patskovska, L, Almo, S.C, Listowsky, I.
Deposit date:2004-11-01
Release date:2004-12-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
1YDK
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BU of 1ydk by Molmil
Crystal structure of the I219A mutant of human glutathione transferase A1-1 with S-hexylglutathione
Descriptor: Glutathione S-transferase A1, S-HEXYLGLUTATHIONE
Authors:Kuhnert, D.C, Sayed, Y, Mosebi, S, Sayed, M, Sewell, T, Dirr, H.W.
Deposit date:2004-12-24
Release date:2005-06-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Tertiary Interactions Stabilise the C-terminal Region of Human Glutathione Transferase A1-1: a Crystallographic and Calorimetric Study.
J.Mol.Biol., 349, 2005
1YJ6
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crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide
Descriptor: GLUTATHIONE, Glutathione S-transferase Mu 1, ZINC ION
Authors:Patskovsky, Y.V, Patskovska, L.N, Listowsky, I, Almo, S.C.
Deposit date:2005-01-13
Release date:2005-02-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human Glutathione S-Transferase M1A-1A Catalyzes Formation of Gsh-Metal Complexes
To be Published
1YKC
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BU of 1ykc by Molmil
human glutathione S-transferase m2-2 (E.C.2.5.1.18) complexed with glutathione-disulfide
Descriptor: Glutathione S-transferase Mu 2, OXIDIZED GLUTATHIONE DISULFIDE
Authors:Patskovsky, Y.V, Patskovska, L.N, Listowsky, I, Almo, S.C.
Deposit date:2005-01-17
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective Inhibitors of Prostaglandin Synthase activity of human glutathione S-transferase M2-2
To be Published
1YY7
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BU of 1yy7 by Molmil
Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor
Descriptor: CITRIC ACID, stringent starvation protein A
Authors:Hansen, A.-M, Gu, Y, Li, M, Andrykovitch, M, Waugh, D.S, Jin, D.J, Ji, X.
Deposit date:2005-02-23
Release date:2005-03-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for the function of stringent starvation protein A as a transcription factor
J.Biol.Chem., 280, 2005
2AB6
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) complexed with S-METHYLGLUTATHIONE
Descriptor: Glutathione S-transferase Mu 2, L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE
Authors:Patskovsky, Y, Almo, S.C, Listowsky, I.
Deposit date:2005-07-14
Release date:2005-08-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Perturbations in the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
2C3N
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BU of 2c3n by Molmil
Human glutathione-S-transferase T1-1, apo form
Descriptor: GLUTATHIONE S-TRANSFERASE THETA 1, IODIDE ION
Authors:Tars, K, Larsson, A.-K, Shokeer, A, Olin, B, Mannervik, B, Kleywegt, G.J.
Deposit date:2005-10-11
Release date:2005-11-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3Q
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Human glutathione-S-transferase T1-1 W234R mutant, complex with S- hexylglutathione
Descriptor: GLUTATHIONE S-TRANSFERASE THETA 1, IODIDE ION, S-HEXYLGLUTATHIONE
Authors:Tars, K, Larsson, A.-K, Shokeer, A, Olin, B, Mannervik, B, Kleywegt, G.J.
Deposit date:2005-10-11
Release date:2005-11-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3T
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Human glutathione-S-transferase T1-1, W234R mutant, apo form
Descriptor: GLUTATHIONE S-TRANSFERASE THETA 1
Authors:Tars, K, Larsson, A.-K, Shokeer, A, Olin, B, Mannervik, B, Kleywegt, G.J.
Deposit date:2005-10-12
Release date:2005-11-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C4J
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Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide conjugate
Descriptor: GLUTATHIONE S-TRANSFERASE MU 2, L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE
Authors:Tars, K, Andersson, M, Ivarsson, Y, Olin, B, Mannervik, B.
Deposit date:2005-10-20
Release date:2005-10-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Alternative Mutations of a Positively Selected Residue Elicit Gain or Loss of Functionalities in Enzyme Evolution.
Proc.Natl.Acad.Sci.USA, 103, 2006

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