1Q1P
| E-Cadherin activation | Descriptor: | CALCIUM ION, Epithelial-cadherin | Authors: | Haussinger, D, Stetefeld, J. | Deposit date: | 2003-07-22 | Release date: | 2004-04-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography. Embo J., 23, 2004
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3QRB
| crystal structure of E-cadherin EC1-2 P5A P6A | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cadherin-1, ... | Authors: | Jin, X, Shapiro, L. | Deposit date: | 2011-02-17 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular design principles underlying beta-strand swapping in the adhesive dimerization of cadherins. Nat.Struct.Mol.Biol., 18, 2011
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3LNE
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3LNF
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3LNI
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3LNH
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3LND
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3LNG
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5ERD
| Crystal structure of human Desmoglein-2 ectodomain | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Brasch, J, Harrison, O.J, Shapiro, L. | Deposit date: | 2015-11-13 | Release date: | 2016-06-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of adhesive binding by desmocollins and desmogleins. Proc.Natl.Acad.Sci.USA, 113, 2016
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6ZTB
| Crystal Structure of human P-Cadherin EC1_EC2 | Descriptor: | CALCIUM ION, Cadherin-3, SODIUM ION | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-17 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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6ZTR
| Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324) | Descriptor: | CALCIUM ION, CQY684 Fab heavy-chain, CQY684 Fab light-chain, ... | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-20 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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5EQX
| Crystal structure of human Desmoglein-3 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Harrison, O.J, Brasch, J, Shapiro, L. | Deposit date: | 2015-11-13 | Release date: | 2016-06-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis of adhesive binding by desmocollins and desmogleins. Proc.Natl.Acad.Sci.USA, 113, 2016
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7STZ
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7SKH
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7SUU
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7A7D
| Cadherin fit into cryo-ET map | Descriptor: | Desmocollin-2, Desmoglein-2 | Authors: | Sikora, M, Ermel, U.H, Seybold, A, Kunz, M, Calloni, G, Reitz, J, Vabulas, R.M, Hummer, G, Frangakis, A.S. | Deposit date: | 2020-08-28 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (26 Å) | Cite: | Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography. Proc.Natl.Acad.Sci.USA, 117, 2020
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7T80
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7SZ8
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7T3S
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5ERP
| Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Harrison, O.J, Brasch, J, Shapiro, L. | Deposit date: | 2015-11-14 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of adhesive binding by desmocollins and desmogleins. Proc.Natl.Acad.Sci.USA, 113, 2016
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3MVS
| Structure of the N-terminus of Cadherin 23 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cadherin-23 | Authors: | Clark, P, Joseph, J.S, Kolatkar, A.R. | Deposit date: | 2010-05-04 | Release date: | 2010-06-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members. Proc.Natl.Acad.Sci.USA, 107, 2010
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2O72
| Crystal Structure Analysis of human E-cadherin (1-213) | Descriptor: | CALCIUM ION, Epithelial-cadherin | Authors: | Parisini, E, Wang, J.-H. | Deposit date: | 2006-12-09 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism J.Mol.Biol., 373, 2007
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2OMU
| Crystal structure of InlA G194S+S Y369S/hEC1 complex | Descriptor: | CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... | Authors: | Wollert, T, Heinz, D.W, Schubert, W.D. | Deposit date: | 2007-01-23 | Release date: | 2007-08-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
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6ULM
| Crystal structure of human cadherin 17 EC1-2 | Descriptor: | CALCIUM ION, Cadherin-17 | Authors: | Gray, M.E, Sotomayor, M. | Deposit date: | 2019-10-08 | Release date: | 2021-03-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism. Acta Crystallogr.,Sect.F, 77, 2021
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6VFV
| Crystal structure of human protocadherin 8 EC5-EC6 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Harrison, O.J, Brasch, J, Shapiro, L. | Deposit date: | 2020-01-06 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell Rep, 30, 2020
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