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2HEV
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BU of 2hev by Molmil
Crystal structure of the complex between OX40L and OX40
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4
著者Hymowitz, S.G, Compaan, D.M.
登録日2006-06-22
公開日2006-08-29
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
5WJF
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BU of 5wjf by Molmil
Crystal structure of murine 4-1BB from HEK293T cells in P21212 space group
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9
著者Zajonc, D.M, Doukov, T, Bitra, A.
登録日2017-07-21
公開日2017-12-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
6A3W
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BU of 6a3w by Molmil
Complex structure of 4-1BB and utomilumab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9, utomilumab VH, ...
著者Li, Y, Tan, S, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
5DMJ
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BU of 5dmj by Molmil
Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB
分子名称: 3H65-5 domain antibody (dAb), POTASSIUM ION, Tumor necrosis factor receptor superfamily member 5
著者Sheriff, S.
登録日2015-09-08
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
J.Mol.Biol., 428, 2016
5DMI
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BU of 5dmi by Molmil
Structure of the extracellular domain of the CD40 in complex with CHI220 FAB
分子名称: Chi220 Fab heavy chain, Chi220 Fab light chain, SULFATE ION, ...
著者Sheriff, S.
登録日2015-09-08
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
J.Mol.Biol., 428, 2016
7MSJ
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BU of 7msj by Molmil
The crystal structure of mouse HVEM
分子名称: SULFATE ION, Tumor necrosis factor receptor superfamily member 14
著者Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C.
登録日2021-05-11
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
3QO4
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BU of 3qo4 by Molmil
The Crystal Structure of Death Receptor 6
分子名称: ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21
著者Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E.
登録日2011-02-09
公開日2011-05-18
最終更新日2012-02-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
3MHD
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BU of 3mhd by Molmil
Crystal structure of DCR3
分子名称: Tumor necrosis factor receptor superfamily member 6B
著者Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
登録日2010-04-07
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3THM
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BU of 3thm by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ...
著者Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
登録日2011-08-19
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3U3Q
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BU of 3u3q by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3U3T
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BU of 3u3t by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2012-07-11
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3S
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BU of 3u3s by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3TJE
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BU of 3tje by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab E09
分子名称: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
著者Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
登録日2011-08-24
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3U3P
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BU of 3u3p by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3V
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BU of 3u3v by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2012-07-11
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
5T2Q
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BU of 5t2q by Molmil
Unliganded Human HVEM at 1.9A in P 1 21 1
分子名称: Tumor necrosis factor receptor superfamily member 14
著者Nemcovicova, I, Zajonc, D.M.
登録日2016-08-24
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unliganded Human HVEM at 1.9A in P 1 21 1
To Be Published
5T2R
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BU of 5t2r by Molmil
Unliganded Human HVEM at 2.1A in P 21 21 21
分子名称: Tumor necrosis factor receptor superfamily member 14
著者Nemcovicova, I, Zajonc, D.M.
登録日2016-08-24
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unliganded Human HVEM at 2.1A in P 21 21 21
To Be Published
5TLJ
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BU of 5tlj by Molmil
COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2016-10-11
公開日2017-02-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
5TL5
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BU of 5tl5 by Molmil
COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2016-10-10
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of CD27 in complex with a neutralizing noncompeting antibody.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5TLK
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BU of 5tlk by Molmil
COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND H2191
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, H2191 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2016-10-11
公開日2017-02-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
3WVT
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BU of 3wvt by Molmil
Structural and biochemical study of equine lentivirus receptor 1
分子名称: ELR1
著者Qian, L.
登録日2014-06-07
公開日2015-06-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structural insight into equine lentivirus receptor 1
Protein Sci., 24, 2015
3X3F
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BU of 3x3f by Molmil
TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Tamada, T.
登録日2015-01-20
公開日2015-12-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2
Sci Rep, 5, 2015
5WI8
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BU of 5wi8 by Molmil
Crystal structure of murine 4-1BB from HEK293T cells in P21 space group
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zajonc, D.M, Bitra, A.
登録日2017-07-18
公開日2017-12-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
5WIW
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BU of 5wiw by Molmil
Crystal structure of murine 4-1BB N128A mutant from HEK293T cells in P43 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ...
著者Zajonc, D.M, Bitra, A.
登録日2017-07-20
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
6MHR
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Structure of the human 4-1BB / Urelumab Fab complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MALONATE ION, ...
著者Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y.
登録日2018-09-18
公開日2018-11-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018

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