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4N78
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BU of 4n78 by Molmil
The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
Descriptor: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ...
Authors:Chen, Z.C.
Deposit date:2013-10-15
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton.
Cell(Cambridge,Mass.), 156, 2014
4M4Z
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BU of 4m4z by Molmil
SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2)
Descriptor: Src-like-adapter 2
Authors:Wybenga-Groot, L.E, McGlade, C.J.
Deposit date:2013-08-07
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation.
Cell Signal, 25, 2013
4LUE
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BU of 4lue by Molmil
Crystal Structure of HCK in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of SKF86002)
Descriptor: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ...
Authors:Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-25
Release date:2014-02-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
4LUD
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Crystal Structure of HCK in complex with the fluorescent compound SKF86002
Descriptor: 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, CHLORIDE ION, ...
Authors:Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-25
Release date:2014-02-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
4LN2
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BU of 4ln2 by Molmil
The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
Descriptor: Sorbin and SH3 domain-containing protein 1, proline rich peptide
Authors:Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LE9
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BU of 4le9 by Molmil
Crystal structure of a chimeric c-Src-SH3 domain
Descriptor: Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Martinez-Rodriguez, S, Ortiz-Salmeron, E, Martin-Garcia, J.M.
Deposit date:2013-06-25
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.344 Å)
Cite:3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops.
J.Struct.Biol., 186, 2014
4K11
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BU of 4k11 by Molmil
The structure of 1NA in complex with Src T338G
Descriptor: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src
Authors:Eck, M.J, Yun, C.H.
Deposit date:2013-04-04
Release date:2014-04-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of 1NA in complex with Src T338G
To be Published
4JZ4
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BU of 4jz4 by Molmil
Crystal structure of chicken c-Src-SH3 domain: monomeric form
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2013-04-02
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4JZ3
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Crystal structure of the chicken c-Src-SH3 domain intertwined dimer
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A.
Deposit date:2013-04-02
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.852 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4JJB
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BU of 4jjb by Molmil
Crystal structure of the Abl-SH3 domain at pH3
Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2013-03-07
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH3
To be Published
4JJD
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BU of 4jjd by Molmil
Crystal structure of the N114A Abl-SH3 domain mutant at pH4
Descriptor: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2013-03-07
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH5
To be Published
4JJC
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Crystal structure of the Abl-SH3 domain at pH5
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2013-03-07
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH5
To be Published
4J9E
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BU of 4j9e by Molmil
Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17
Descriptor: P17, SULFATE ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17
To be Published
4J9B
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BU of 4j9b by Molmil
Crystal structure of the Abl-SH3 domain H59Q-N96T mutant
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Crystal structure of the Abl-SH3 domain H59Q-N96T mutant
To be Published
4J9D
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BU of 4j9d by Molmil
Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0
Descriptor: P0, SULFATE ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0
To be Published
4J9C
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BU of 4j9c by Molmil
Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17
Descriptor: DI(HYDROXYETHYL)ETHER, P17, TRIETHYLENE GLYCOL, ...
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.051 Å)
Cite:Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17
To be Published
4J9H
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BU of 4j9h by Molmil
Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH 8
Descriptor: P7, SULFATE ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7
To be Published
4J9G
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BU of 4j9g by Molmil
Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH7
Descriptor: GLYCEROL, P7, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7
To be Published
4J9F
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BU of 4j9f by Molmil
Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0
Descriptor: GLYCEROL, P0, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.094 Å)
Cite:Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0
To be Published
4J9I
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BU of 4j9i by Molmil
Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17
Descriptor: GLYCEROL, P17, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2013-02-16
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17
To be Published
2M51
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BU of 2m51 by Molmil
NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1
Descriptor: Ras GTPase-activating protein 1
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-02-12
Release date:2013-03-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1
To be Published
4IIM
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BU of 4iim by Molmil
Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide
Descriptor: Intersectin-1, UNKNOWN ATOM OR ION, peptide ligand
Authors:Dong, A, Guan, X, Huang, H, Wernimont, A, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2012-12-20
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide
To be Published
4HXJ
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BU of 4hxj by Molmil
Crystal structure of SH3:RGT complex
Descriptor: C-terminal 3-mer peptide from Integrin beta-3, Proto-oncogene tyrosine-protein kinase Src
Authors:Xiao, R, Meng, G.
Deposit date:2012-11-11
Release date:2012-11-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural framework of c-Src activation by integrin beta 3
Blood, 121, 2013
2M0Y
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BU of 2m0y by Molmil
Solution structure of the SH3 domain of DOCK180
Descriptor: Dedicator of cytokinesis protein 1
Authors:Liu, X, Wen, W.
Deposit date:2012-11-08
Release date:2012-12-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of DOCK180.
Proteins, 81, 2013
4HVV
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BU of 4hvv by Molmil
Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide APP12
Descriptor: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, SYNTHETIC PEPTIDE Acetyl-APPLPPRNRP
Authors:Camara-Artigas, A.
Deposit date:2012-11-07
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II.
Acta Crystallogr.,Sect.D, 69, 2013

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