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1AWX
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BU of 1awx by Molmil
SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: BRUTON'S TYROSINE KINASE
Authors:Hansson, H, Mattsson, P.T, Allard, P, Haapaniemi, P, Vihinen, M, Smith, C.I.E, Hard, T.
Deposit date:1997-10-06
Release date:1998-04-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain from Bruton's tyrosine kinase.
Biochemistry, 37, 1998
1AWO
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BU of 1awo by Molmil
THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES
Descriptor: ABL TYROSINE KINASE
Authors:Cowburn, D.
Deposit date:1997-10-03
Release date:1998-01-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct.
Structure, 3, 1995
1AWJ
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BU of 1awj by Molmil
INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: ITK
Authors:Andreotti, A.H, Bunnell, S.C, Feng, S, Berg, L.J, Schreiber, S.L.
Deposit date:1997-10-02
Release date:1998-01-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Regulatory intramolecular association in a tyrosine kinase of the Tec family.
Nature, 385, 1997
1AVZ
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BU of 1avz by Molmil
V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN
Descriptor: FYN TYROSINE KINASE, NEGATIVE FACTOR
Authors:Arold, S, Franken, P, Dumas, C.
Deposit date:1997-09-23
Release date:1998-03-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997
1AOJ
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BU of 1aoj by Molmil
THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER
Descriptor: EPS8
Authors:Kishan, K.V.R, Newcomer, M.E.
Deposit date:1997-07-07
Release date:1998-07-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The SH3 domain of Eps8 exists as a novel intertwined dimer.
Nat.Struct.Biol., 4, 1997
2PTK
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BU of 2ptk by Molmil
CHICKEN SRC TYROSINE KINASE
Descriptor: TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC
Authors:Williams, J.C, Wierenga, R.
Deposit date:1997-06-17
Release date:1997-12-24
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions
J.Mol.Biol., 274, 1997
1AEY
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BU of 1aey by Molmil
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES
Descriptor: ALPHA-SPECTRIN
Authors:Blanco, F.J, Ortiz, A.R, Serrano, L.
Deposit date:1997-03-02
Release date:1997-05-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure.
J.Biomol.NMR, 9, 1997
2HCK
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BU of 2hck by Molmil
SRC FAMILY KINASE HCK-QUERCETIN COMPLEX
Descriptor: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, CALCIUM ION, HEMATOPOETIC CELL KINASE HCK
Authors:Sicheri, F, Moarefi, I, Kuriyan, J.
Deposit date:1997-02-25
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the Src family tyrosine kinase Hck.
Nature, 385, 1997
1AD5
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BU of 1ad5 by Molmil
SRC FAMILY KINASE HCK-AMP-PNP COMPLEX
Descriptor: CALCIUM ION, HAEMATOPOETIC CELL KINASE HCK, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Sicheri, F, Moarefi, I, Kuriyan, J.
Deposit date:1997-02-20
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the Src family tyrosine kinase Hck.
Nature, 385, 1997
1FMK
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BU of 1fmk by Molmil
CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC
Descriptor: TYROSINE-PROTEIN KINASE SRC
Authors:Xu, W, Harrison, S.C, Eck, M.J.
Deposit date:1997-01-24
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Three-dimensional structure of the tyrosine kinase c-Src.
Nature, 385, 1997
1GBQ
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BU of 1gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
3GBQ
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BU of 3gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
4GBQ
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BU of 4gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
2GBQ
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BU of 2gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
2ABL
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BU of 2abl by Molmil
SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE
Descriptor: ABL TYROSINE KINASE
Authors:Nam, H.-J, Frederick, C.A.
Deposit date:1996-11-17
Release date:1997-09-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism.
Structure, 4, 1996
1YCS
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BU of 1ycs by Molmil
P53-53BP2 COMPLEX
Descriptor: 53BP2, P53, ZINC ION
Authors:Gorina, S, Pavletich, N.P.
Deposit date:1996-09-30
Release date:1997-11-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.
Science, 274, 1996
1NLP
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BU of 1nlp by Molmil
STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: C-SRC, NL2 (MN8-MN1-PLPPLP)
Authors:Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L.
Deposit date:1996-08-04
Release date:1997-01-27
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis.
Chem.Biol., 3, 1996
1NLO
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BU of 1nlo by Molmil
STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: C-SRC, NL1 (MN7-MN2-MN1-PLPPLP)
Authors:Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L.
Deposit date:1996-08-04
Release date:1997-01-27
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis.
Chem.Biol., 3, 1996
1EFN
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BU of 1efn by Molmil
HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
Descriptor: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1996-06-29
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996
1NYG
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BU of 1nyg by Molmil
NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, FAMILY OF 20 STRUCTURES
Descriptor: FYN
Authors:Morton, C.J, Pugh, D.J.R, Campbell, I.D.
Deposit date:1996-04-22
Release date:1996-11-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and peptide binding of the SH3 domain from human Fyn.
Structure, 4, 1996
1NYF
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BU of 1nyf by Molmil
NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE
Descriptor: FYN
Authors:Morton, C.J, Pugh, D.J.R, Campbell, I.D.
Deposit date:1996-04-22
Release date:1996-11-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and peptide binding of the SH3 domain from human Fyn.
Structure, 4, 1996
1TUD
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BU of 1tud by Molmil
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
Descriptor: ALPHA-SPECTRIN
Authors:Viguera, A.R, Serrano, L, Wilmanns, M.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1TUC
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BU of 1tuc by Molmil
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20
Descriptor: ALPHA-SPECTRIN
Authors:Wilmanns, M, Serrano, L, Viguera, A.R.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1QWE
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BU of 1qwe by Molmil
C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND APP12
Descriptor: ALA-PRO-PRO-LEU-PRO-PRO-ARG-ASN-ARG-PRO-ARG-LEU, TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC
Authors:Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L.
Deposit date:1995-11-09
Release date:1996-03-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands.
Proc.Natl.Acad.Sci.USA, 92, 1995
1QWF
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BU of 1qwf by Molmil
C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND VSL12
Descriptor: TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC, VAL-SER-LEU-ALA-ARG-ARG-PRO-LEU-PRO-PRO-LEU-PRO
Authors:Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L.
Deposit date:1995-11-09
Release date:1996-03-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands.
Proc.Natl.Acad.Sci.USA, 92, 1995

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