PDB: 522 件ウェブページステータス検索Chemie searchBIRD

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5QU1	Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A 分子名称: Cytoplasmic protein NCK1, SULFATE ION 著者 Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU5	Domain Swap in the first SH3 domain of human Nck1 分子名称: Cytoplasmic protein NCK1 著者 Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU2	Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY 分子名称: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU7	Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU4	Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
4IIM	Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide 分子名称: Intersectin-1, UNKNOWN ATOM OR ION, peptide ligand 著者 Dong, A, Guan, X, Huang, H, Wernimont, A, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2012-12-20 公開日 2013-01-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide To be Published
1ABO	CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE 分子名称: 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ABL TYROSINE KINASE, ... 著者 Musacchio, A, Wilmanns, M, Saraste, M. 登録日 1995-05-19 公開日 1995-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
4J9E	Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 分子名称: P17, SULFATE ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 To be Published
1A0N	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES 分子名称: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR 著者 Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. 登録日 1997-12-05 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
4J9B	Crystal structure of the Abl-SH3 domain H59Q-N96T mutant 分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Crystal structure of the Abl-SH3 domain H59Q-N96T mutant To be Published
1AEY	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES 分子名称: ALPHA-SPECTRIN 著者 Blanco, F.J, Ortiz, A.R, Serrano, L. 登録日 1997-03-02 公開日 1997-05-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure. J.Biomol.NMR, 9, 1997
4JJB	Crystal structure of the Abl-SH3 domain at pH3 分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the Abl-SH3 domain at pH3 To be Published
4J9D	Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0 分子名称: P0, SULFATE ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0 To be Published
1ABQ	CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN 分子名称: ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN 著者 Musacchio, A, Wilmanns, M, Saraste, M. 登録日 1995-05-19 公開日 1995-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
4J9C	Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 分子名称: DI(HYDROXYETHYL)ETHER, P17, TRIETHYLENE GLYCOL, ... 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.051 Å) 主引用文献 Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 To be Published
4J9H	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH 8 分子名称: P7, SULFATE ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
4J9G	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH7 分子名称: GLYCEROL, P7, SULFATE ION, ... 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
1BBZ	CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS 分子名称: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION 著者 Pisabarro, M.T, Serrano, L, Wilmanns, M. 登録日 1998-04-28 公開日 1998-11-25 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions. J.Mol.Biol., 281, 1998
4JJD	Crystal structure of the N114A Abl-SH3 domain mutant at pH4 分子名称: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Abl-SH3 domain at pH5 To be Published
1B07	CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR 分子名称: PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) 著者 Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. 登録日 1998-11-17 公開日 1999-01-06 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
4JJC	Crystal structure of the Abl-SH3 domain at pH5 分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Abl-SH3 domain at pH5 To be Published
4J9F	Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0 分子名称: GLYCEROL, P0, SULFATE ION, ... 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.094 Å) 主引用文献 Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0 To be Published
4J9I	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17 分子名称: GLYCEROL, P17, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17 To be Published
1AWJ	INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: ITK 著者 Andreotti, A.H, Bunnell, S.C, Feng, S, Berg, L.J, Schreiber, S.L. 登録日 1997-10-02 公開日 1998-01-14 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature, 385, 1997
4JZ4	Crystal structure of chicken c-Src-SH3 domain: monomeric form 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A. 登録日 2013-04-02 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014

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