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5IZL
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The crystal structure of human eEFSec in complex with GDPCP
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Selenocysteine-specific elongation factor
著者Dobosz-Bartoszek, M, Simonovic, M.
登録日2016-03-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5IZM
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The crystal structure of human eEFSec in complex with GDPNP
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Selenocysteine-specific elongation factor
著者Dobosz-Bartoszek, M, Otwinowski, Z, Simonovic, M.
登録日2016-03-25
公開日2016-10-12
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5IZK
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The crystal structure of human eEFSec in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Selenocysteine-specific elongation factor
著者Dobosz-Bartoszek, M, Simonovic, M.
登録日2016-03-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5J8B
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BU of 5j8b by Molmil
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Lin, J, Steitz, T.A.
登録日2016-04-07
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Elongation factor 4 remodels the A-site tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JBQ
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EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH THIOMURACIN ANALOG
分子名称: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Palestrant, D, Stams, T.
登録日2016-04-13
公開日2016-07-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Antibacterial and Solubility Optimization of Thiomuracin A.
J.Med.Chem., 59, 2016
5JB3
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Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-REMOTE conformation
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Coureux, P.-D, Schmitt, E, Mechulam, Y.
登録日2016-04-13
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.34 Å)
主引用文献Cryo-EM study of start codon selection during archaeal translation initiation.
Nat Commun, 7, 2016
1IJE
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BU of 1ije by Molmil
Nucleotide Exchange Intermediates in the eEF1A-eEF1Ba Complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, elongation factor 1-alpha, elongation factor 1-beta
著者Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
登録日2001-04-26
公開日2001-05-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJF
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Nucleotide exchange mechanisms in the eEF1A-eEF1Ba complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, elongation factor 1-alpha, ...
著者Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
登録日2001-04-26
公開日2001-05-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1JQM
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Fitting of L11 protein and elongation factor G (EF-G) in the cryo-em map of e. coli 70S ribosome bound with EF-G, GDP and fusidic acid
分子名称: 50S Ribosomal protein L11, Elongation Factor G
著者Agrawal, R.K, Linde, J, Segupta, J, Nierhaus, K.H, Frank, J.
登録日2001-08-07
公開日2001-09-07
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation.
J.Mol.Biol., 311, 2001
1JNY
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BU of 1jny by Molmil
Crystal structure of Sulfolobus solfataricus elongation factor 1 alpha in complex with GDP
分子名称: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE
著者Vitagliano, L, Masullo, M, Sica, F, Zagari, A, Bocchini, V.
登録日2001-07-26
公開日2002-01-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange.
EMBO J., 20, 2001
1KK0
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Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi
分子名称: ZINC ION, eIF2gamma
著者Schmitt, E, Blanquet, S, Mechulam, Y.
登録日2001-12-06
公開日2002-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KK3
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Structure of the wild-type large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi complexed with GDP-Mg2+
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
著者Schmitt, E, Blanquet, S, Mechulam, Y.
登録日2001-12-06
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
5W75
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BU of 5w75 by Molmil
Crystal Structure of Reconstructed Bacterial Elongation Factor Node 168
分子名称: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ortlund, E.A.
登録日2017-06-19
公開日2018-04-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Structural and Dynamics Comparison of Thermostability in Ancient, Modern, and Consensus Elongation Factor Tus.
Structure, 26, 2018
5WE4
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BU of 5we4 by Molmil
70S ribosome-EF-Tu wt complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE6
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70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-06
公開日2018-04-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5XJC
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BU of 5xjc by Molmil
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y.
登録日2017-04-30
公開日2017-07-05
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
8OZ0
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BU of 8oz0 by Molmil
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V.
登録日2023-05-06
公開日2024-02-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
Nat.Struct.Mol.Biol., 31, 2024
8P2G
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BU of 8p2g by Molmil
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane with a tRNA in pe/E chimeric state
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2023-05-16
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.02 Å)
主引用文献Cryo-EM structures of Staphylococcus aureus 70S ribosomes in complex with elongation factor G and fusidic acid
To Be Published
8P2H
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BU of 8p2h by Molmil
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric state
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2023-05-16
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric hybrid state
To Be Published
8P2F
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BU of 8p2f by Molmil
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane in post-translocational state
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2023-05-16
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Cryo-EM structures of Staphylococcus aureus 70S ribosomes in complex with elongation factor G and fusidic acid
To Be Published
5YT0
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BU of 5yt0 by Molmil
Crystal structure of the complex of archaeal ribosomal stalk protein aP1 and archaeal translation initiation factor aIF5B
分子名称: Archaeal ribosomal stalk protein aP1, GUANOSINE-5'-DIPHOSPHATE, Probable translation initiation factor IF-2
著者Murakami, R, Singh, C.R, Morris, J, Tang, L, Harmon, I, Miyoshi, T, Ito, K, Asano, K, Uchiumi, T.
登録日2017-11-16
公開日2018-06-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The Interaction between the Ribosomal Stalk Proteins and Translation Initiation Factor 5B Promotes Translation Initiation
Mol. Cell. Biol., 38, 2018
5YLZ
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BU of 5ylz by Molmil
Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
登録日2017-10-20
公開日2018-07-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
登録日2023-07-07
公開日2023-10-18
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8QFS
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Cryo-EM structure of SidH from Legionella pneumophila
分子名称: Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Sharma, R, Weis, F, Bhogaraju, S.
登録日2023-09-04
公開日2023-10-11
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023

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