5JBQ
EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH THIOMURACIN ANALOG
Summary for 5JBQ
Entry DOI | 10.2210/pdb5jbq/pdb |
Descriptor | Elongation factor Tu 1, THIOMURACIN ANALOG, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | natural product inhibitor, elongation factor, rna binding protein-antimicrobial complex, rna binding protein/antimicrobial |
Biological source | Escherichia coli (strain K12) More |
Cellular location | Cytoplasm: P0CE47 |
Total number of polymer chains | 2 |
Total formula weight | 45432.04 |
Authors | Palestrant, D.,Stams, T. (deposition date: 2016-04-13, release date: 2016-07-13, Last modification date: 2023-11-15) |
Primary citation | LaMarche, M.J.,Leeds, J.A.,Brewer, J.,Dean, K.,Ding, J.,Dzink-Fox, J.,Gamber, G.,Jain, A.,Kerrigan, R.,Krastel, P.,Lee, K.,Lombardo, F.,McKenney, D.,Neckermann, G.,Osborne, C.,Palestrant, D.,Patane, M.A.,Rann, E.M.,Robinson, Z.,Schmitt, E.,Stams, T.,Tiamfook, S.,Yu, D.,Whitehead, L. Antibacterial and Solubility Optimization of Thiomuracin A. J.Med.Chem., 59:6920-6928, 2016 Cited by PubMed: 27355833DOI: 10.1021/acs.jmedchem.6b00726 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.006 Å) |
Structure validation
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