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8TI2
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BU of 8ti2 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
著者Driggers, C.M, Shyng, S.-L.
登録日2023-07-18
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8J5Q
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BU of 8j5q by Molmil
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the pre-translocation state
分子名称: Endogenous oligopeptide, IRON/SULFUR CLUSTER, Putative peptide transport permease protein Rv1282c, ...
著者Yang, X, Hu, T, Zhang, B, Rao, Z.
登録日2023-04-24
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality.
Nat.Struct.Mol.Biol., 2024
8J5S
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BU of 8j5s by Molmil
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the pre-catalytic intermediate state
分子名称: Endogenous oligopeptide, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
著者Yang, X, Hu, T, Zhang, B, Rao, Z.
登録日2023-04-24
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality.
Nat.Struct.Mol.Biol., 2024
8J5R
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BU of 8j5r by Molmil
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the resting state
分子名称: IRON/SULFUR CLUSTER, Putative peptide transport permease protein Rv1282c, Putative peptide transport permease protein Rv1283c, ...
著者Yang, X, Hu, T, Zhang, B, Rao, Z.
登録日2023-04-24
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality.
Nat.Struct.Mol.Biol., 2024
8J5T
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BU of 8j5t by Molmil
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the catalytic intermediate state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
著者Yang, X, Hu, T, Zhang, B, Rao, Z.
登録日2023-04-24
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality.
Nat.Struct.Mol.Biol., 2024
8P03
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BU of 8p03 by Molmil
48S late-stage initiation complex with m6A mRNA
分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y.
登録日2023-05-09
公開日2024-03-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献N 6 -methyladenosine in 5' UTR does not promote translation initiation.
Mol.Cell, 84, 2024
8P09
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BU of 8p09 by Molmil
48S late-stage initiation complex with non methylated mRNA
分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y.
登録日2023-05-09
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献N 6 -methyladenosine in 5' UTR does not promote translation initiation.
Mol.Cell, 84, 2024
8PEE
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BU of 8pee by Molmil
ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC
分子名称: (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ATP-dependent translocase ABCB1, ...
著者Parey, K, Januliene, D, Gewering, T, Moeller, A.
登録日2023-06-13
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Tracing the substrate translocation mechanism in P-glycoprotein.
Elife, 12, 2024
8WP0
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BU of 8wp0 by Molmil
Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state
分子名称: ABC transporter B family member 19, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Ying, W, Wei, H, Liu, X, Sun, L.
登録日2023-10-08
公開日2024-03-13
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOO
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BU of 8woo by Molmil
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state
分子名称: ABC transporter B family member 19, Brassinolide, MAGNESIUM ION, ...
著者Ying, W, Wei, H, Liu, X, Sun, L.
登録日2023-10-07
公開日2024-03-13
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOM
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BU of 8wom by Molmil
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state
分子名称: ABC transporter B family member 19, Brassinolide
著者Ying, W, Wei, H, Liu, X, Sun, L.
登録日2023-10-07
公開日2024-03-13
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOI
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BU of 8woi by Molmil
Structure of the wild-type Arabidopsis ABCB19 in the apo state
分子名称: ABC transporter B family member 19
著者Ying, W, Wei, H, Liu, X, Sun, L.
登録日2023-10-07
公開日2024-03-13
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8SG4
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BU of 8sg4 by Molmil
E1435Q Ycf1 mutant in dephosphorylated state
分子名称: Metal resistance protein YCF1
著者Khandelwal, N.K, Tomasiak, T.M.
登録日2023-04-11
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献E1435Q Ycf1 mutant in dephosphorylated state
To Be Published
8W9M
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BU of 8w9m by Molmil
Cryo-EM structure of the cyanobacterial nitrate transporter NrtBCD in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrate transport ATP-binding protein, ...
著者Li, B, Zhou, C.Z, Chen, Y.X, Jiang, Y.L.
登録日2023-09-05
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Allosteric regulation of nitrate transporter NRT via the signaling protein PII.
Proc.Natl.Acad.Sci.USA, 121, 2024
8WM8
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BU of 8wm8 by Molmil
Cryo-EM structure of cyanobacterial nitrate/nitrite transporter NrtBCD in complex with nitrate
分子名称: NITRATE ION, Nitrate transport ATP-binding protein, Nitrate transport permease protein
著者Li, B, Zhou, C.Z, Chen, Y.X, Jiang, Y.L.
登録日2023-10-03
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Allosteric regulation of nitrate transporter NRT via the signaling protein PII.
Proc.Natl.Acad.Sci.USA, 121, 2024
8WM7
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BU of 8wm7 by Molmil
Cryo-EM structure of cyanobacterial nitrate/nitrite transporter NrtBCD in complex with signalling protein PII
分子名称: ADENOSINE-5'-DIPHOSPHATE, Nitrate transport ATP-binding protein, Nitrate transport permease protein, ...
著者Li, B, Zhou, C.Z, Chen, Y.X, Jiang, Y.L.
登録日2023-10-03
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Allosteric regulation of nitrate transporter NRT via the signaling protein PII.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UBR
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BU of 8ubr by Molmil
Complex of the phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with CFTRinh-172 and ATP/Mg
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 4-[(Z)-{(3M)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Young, P.G, Fiedorczuk, K, Chen, J.
登録日2023-09-24
公開日2024-02-21
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for CFTR inhibition by CFTR inh -172.
Proc.Natl.Acad.Sci.USA, 121, 2024
8RQ3
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BU of 8rq3 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)
分子名称: ATP-binding cassette sub-family C member 2
著者Mazza, T, Beis, K.
登録日2024-01-17
公開日2024-02-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RQ4
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BU of 8rq4 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex with probenecid
分子名称: 4-(dipropylsulfamoyl)benzoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL HEMISUCCINATE
著者Mazza, T, Beis, K.
登録日2024-01-17
公開日2024-02-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8SWN
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BU of 8swn by Molmil
Bovine multidrug resistance protein 4 (MRP4) E1202Q mutant bound to ATP in MSP lipid nanodisc
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP binding cassette subfamily C member 4, MAGNESIUM ION, ...
著者Pourmal, S, Stroud, R.M.
登録日2023-05-19
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX9
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BU of 8sx9 by Molmil
Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
分子名称: Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SXB
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BU of 8sxb by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SXA
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BU of 8sxa by Molmil
Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
分子名称: Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX8
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BU of 8sx8 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc
分子名称: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX7
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BU of 8sx7 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc
分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024

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件を2024-05-22に公開中

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