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7T57
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BU of 7t57 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing narrow conformation under ATP turnover condition
Descriptor: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kieuvongngam, V, Chen, J.
Deposit date:2021-12-11
Release date:2022-02-02
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T54
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BU of 7t54 by Molmil
Cryo-EM structure of ATP-bound PCAT1 in the outward-facing conformation
Descriptor: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE
Authors:Kieuvongngam, V, Chen, J.
Deposit date:2021-12-11
Release date:2022-02-02
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T56
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BU of 7t56 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing intermediate conformation under ATP turnover condition
Descriptor: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kieuvongngam, V, Chen, J.
Deposit date:2021-12-11
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
8SG4
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BU of 8sg4 by Molmil
E1435Q Ycf1 mutant in dephosphorylated state
Descriptor: Metal resistance protein YCF1
Authors:Khandelwal, N.K, Tomasiak, T.M.
Deposit date:2023-04-11
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:E1435Q Ycf1 mutant in dephosphorylated state
To Be Published
7TCG
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BU of 7tcg by Molmil
BceAB nucleotide-free conformation
Descriptor: 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2E,6E,10Z,14Z,18Z,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose, Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB
Authors:George, N.L, Orlando, B.J.
Deposit date:2021-12-23
Release date:2022-04-06
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational snapshots of the bacitracin sensing and resistance transporter BceAB.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TCH
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BU of 7tch by Molmil
BceAB E169Q variant ATP-bound conformation
Descriptor: 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2E,6E,10Z,14Z,18Z,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose, ADENOSINE-5'-TRIPHOSPHATE, Bacitracin export ATP-binding protein BceA, ...
Authors:George, N.L, Orlando, B.J.
Deposit date:2021-12-23
Release date:2022-04-06
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Conformational snapshots of the bacitracin sensing and resistance transporter BceAB.
Proc.Natl.Acad.Sci.USA, 119, 2022
8SXB
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BU of 8sxb by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc
Descriptor: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SWN
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BU of 8swn by Molmil
Bovine multidrug resistance protein 4 (MRP4) E1202Q mutant bound to ATP in MSP lipid nanodisc
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP binding cassette subfamily C member 4, MAGNESIUM ION, ...
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-19
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX7
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BU of 8sx7 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc
Descriptor: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX9
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BU of 8sx9 by Molmil
Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
Descriptor: Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
7TDT
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BU of 7tdt by Molmil
Cryo-EM structure of nanodisc-embedded human ABCA1
Descriptor: Phospholipid-transporting ATPase ABCA1
Authors:Plummer, A.M, Culbertson, A.T, Morales-Perez, C.L, Liao, M.
Deposit date:2022-01-03
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Activity and Structural Dynamics of Human ABCA1 in a Lipid Membrane.
J.Mol.Biol., 435, 2023
7Y1M
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BU of 7y1m by Molmil
Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the inward-facing conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ...
Authors:Chen, L, Ding, D, Hou, T.
Deposit date:2022-06-08
Release date:2023-06-14
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7Y1N
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BU of 7y1n by Molmil
Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the partially occluded state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ...
Authors:Chen, L, Ding, D, Hou, T.
Deposit date:2022-06-08
Release date:2023-06-14
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7NNT
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BU of 7nnt by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2021-02-25
Release date:2021-08-18
Last modified:2021-09-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NNU
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BU of 7nnu by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs
Descriptor: Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2021-02-25
Release date:2021-08-18
Last modified:2021-09-22
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NIW
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BU of 7niw by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-02-14
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NIV
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BU of 7niv by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation)
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-02-14
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NIU
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BU of 7niu by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)
Descriptor: 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, CHOLESTEROL, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-02-14
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7Z19
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BU of 7z19 by Molmil
E. coli C-P lyase bound to a single PhnK ABC domain
Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-05-25
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7Z18
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BU of 7z18 by Molmil
E. coli C-P lyase bound to a PhnK ABC dimer and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-05-25
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7Z17
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BU of 7z17 by Molmil
E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation
Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-05-25
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7Z16
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BU of 7z16 by Molmil
E. coli C-P lyase bound to PhnK/PhnL dual ABC dimer with AMPPNP and PhnK E171Q mutation
Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI, ...
Authors:Amstrup, S.K, Sofus, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-06-22
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7Z15
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BU of 7z15 by Molmil
E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-06-22
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (1.93 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7N58
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BU of 7n58 by Molmil
Structure of AtAtm3 in the inward-facing conformation
Descriptor: ABC transporter B family member 25, mitochondrial
Authors:Fan, C, Rees, D.C.
Deposit date:2021-06-05
Release date:2022-04-13
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters.
Elife, 11, 2022
7N59
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BU of 7n59 by Molmil
Structure of AtAtm3 in the inward-facing conformation with GSSG bound
Descriptor: ABC transporter B family member 25, mitochondrial, OXIDIZED GLUTATHIONE DISULFIDE
Authors:Fan, C, Rees, D.C.
Deposit date:2021-06-05
Release date:2022-04-13
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters.
Elife, 11, 2022

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