PDB: 653 resultsInfo pagesStatus searchChemie searchBIRD

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7AJT	Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. Deposit date: 2020-09-29 Release date: 2020-12-30 Last modified: 2021-02-03 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
7BPB	Human AAA+ ATPase VCP mutant - T76E, AMP-PNP bound form, Conformation I Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-22 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
7BPA	Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-21 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
7BP9	Human AAA+ ATPase VCP mutant - T76E, ADP-bound form Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-21 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
7BP8	Human AAA+ ATPase VCP mutant - T76A, ADP-bound form Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-21 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
6W20	ClpAP Disengaged State bound to RepA-GFP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... Authors: Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. Deposit date: 2020-03-04 Release date: 2020-05-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
6W21	ClpAP Engaged2 State bound to RepA-GFP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... Authors: Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. Deposit date: 2020-03-04 Release date: 2020-05-13 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
6W22	ClpA Engaged1 State bound to RepA-GFP (ClpA Focused Refinement) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... Authors: Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. Deposit date: 2020-03-04 Release date: 2020-04-29 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
6VVO	Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A. Deposit date: 2020-02-18 Release date: 2020-02-26 Last modified: 2020-03-25 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism Biorxiv, 2020
6W1Z	ClpAP Engaged1 State bound to RepA-GFP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... Authors: Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. Deposit date: 2020-03-04 Release date: 2020-05-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
6W23	ClpA Disengaged State bound to RepA-GFP (Focused Classification) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... Authors: Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. Deposit date: 2020-03-04 Release date: 2020-05-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
6W24	ClpA Engaged2 State bound to RepA-GFP (Focused Classification) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... Authors: Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. Deposit date: 2020-03-04 Release date: 2020-05-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
6W6G	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation I in the presence of DnaK chaperone and a model substrate Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Yin, Y, Li, H. Deposit date: 2020-03-16 Release date: 2021-03-17 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6H	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation II in the presence of DnaK chaperone and a model substrate Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Yin, Y, Li, H. Deposit date: 2020-03-16 Release date: 2021-05-26 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6E	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined ClpB middle domain and a DnaK nucleotide binding domain Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ... Authors: Yin, Y, Li, H. Deposit date: 2020-03-16 Release date: 2021-05-26 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6J	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined N-terminal domain in the presence of DnaK chaperone and a model substrate Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Yin, Y, Li, H. Deposit date: 2020-03-17 Release date: 2021-05-26 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6W6I	The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation T in the presence of DnaK chaperone and a model substrate Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Yin, Y, Li, H. Deposit date: 2020-03-17 Release date: 2021-05-26 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
6WGI	Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... Authors: Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. Deposit date: 2020-04-05 Release date: 2020-07-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (10 Å) Cite: Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
6WJD	SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Chen, X, Walters, K.J. Deposit date: 2020-04-13 Release date: 2020-08-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome. Structure, 28, 2020
6WGC	Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) Descriptor: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ... Authors: Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. Deposit date: 2020-04-05 Release date: 2020-07-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
6WGG	Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ... Authors: Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. Deposit date: 2020-04-05 Release date: 2020-07-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (8.1 Å) Cite: Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
6WJN	SD-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Chen, X, Walters, K.J. Deposit date: 2020-04-14 Release date: 2020-08-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome. Structure, 28, 2020
6WQH	Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ig2 substrate, Lon protease, ... Authors: Zhang, K, Li, S, Hsiehb, K, Sub, S, Pintilie, G, Chiu, W, Chang, C. Deposit date: 2020-04-28 Release date: 2021-06-09 Last modified: 2021-11-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease. J.Biol.Chem., 297, 2021
7CTF	Human origin recognition complex 1-5 State II Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... Authors: Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. Deposit date: 2020-08-18 Release date: 2021-01-06 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
7CTG	Human Origin Recognition Complex, ORC1-5 State I Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... Authors: Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. Deposit date: 2020-08-18 Release date: 2021-01-06 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (5 Å) Cite: Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020

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